Subtype-specific transcription factors are clinically relevant and show distinct therapeutic vulnerabilities in human small cell lung cancer

Autor: C Lang, Z Megyesfalvi, B Szeitz, A Lantos, N Woldmar, Z Valko, A Schwendenwein, F Oberndorfer, N Barany, S Paku, V Laszlo, H Kiss, E Bugyik, B Ferencz, K Dezso, Z Lohinai, J Moldvay, J Fillinger, G Galffy, C Rivard, F R Hirsch, L Brcic, H Popper, I Kern, M Kovacevic, J Skarda, M Mittak, A M Szasz, L Pizzatti, K Bogos, M A Hoda, K Hoetzenecker, G Marko-Varga, P Horvatovics, F Renyi-Vamos, T Klikovits, K Schelch, M Rezeli, B Döme

Publikováno v: 11.01 - Lung cancer.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::944234d32d6a9f7e6ca2b157ef46471d
https://doi.org/10.1183/13993003.congress-2022.3828

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Mitochondrial dysfunction and immune suppression in BRAF V600E-mutated metastatic melanoma.

Autor: Pinto de Almeida N; Laboratory of Proteomics/LADETEC, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil.; Proteomics Unit, Institute of Chemistry, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil.; Clinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, Lund, Sweden., Jánosi ÁJ; Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary., Hong R; Institute for Systems Genetics, NYU Grossman School of Medicine, New York City, New York, USA.; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York City, New York, USA., Rajeh A; Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Nogueira F; Laboratory of Proteomics/LADETEC, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil.; Proteomics Unit, Institute of Chemistry, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil., Szadai L; Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary., Szeitz B; Department of Internal Medicine and Oncology, Semmelweis University, Budapest, Hungary., Pla Parada I; Section for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden., Doma V; 2nd Department of Pathology, Semmelweis University, Budapest, Hungary.; Department of Dermatology, Venerology and Dermatooncology, Semmelweis University, Budapest, Hungary., Woldmar N; Clinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, Lund, Sweden., Guedes J; Laboratory of Proteomics/LADETEC, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil.; Proteomics Unit, Institute of Chemistry, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil.; Section for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden., Újfaludi Z; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.; Competence Centre of the Life Sciences Cluster of the Centre of Excellence for Interdisciplinary Research, Development and Innovation, University of Szeged, Szeged, Hungary., Bartha A; Department of Bioinformatics, Semmelweis University, Budapest, Hungary., Kim Y; Data Convergence Drug Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, South Korea.; Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden., Welinder C; Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden., Baldetorp B; Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden., Kemény LV; Department of Dermatology, Venerology and Dermatooncology, Semmelweis University, Budapest, Hungary.; HCEMM-SU Translational Dermatology Research Group, Semmelweis University, Budapest, Hungary.; Department of Physiology, Semmelweis University, Budapest, Hungary., Pahi Z; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary., Wan G; Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Nguyen N; Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Pankotai T; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.; Competence Centre of the Life Sciences Cluster of the Centre of Excellence for Interdisciplinary Research, Development and Innovation, University of Szeged, Szeged, Hungary.; Genome Integrity and DNA Repair Core Group, Hungarian Centre of Excellence for Molecular Medicine (HCEMM), University of Szeged, Szeged, Hungary., Győrffy B; Department of Bioinformatics, Semmelweis University, Budapest, Hungary.; Cancer Biomarker Research Group, Research Centre for Natural Sciences, Budapest, Hungary.; Department of Biophysics, Medical School, University of Pecs, Pecs, Hungary., Pawłowski K; Section for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden.; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Department of Biochemistry and Microbiology, Warsaw University of Life Sciences, Warsaw, Poland., Horvatovich P; Clinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, Lund, Sweden.; Department of Analytical Biochemistry, Faculty of Science and Engineering, University of Groningen, Groningen, The Netherlands., Szasz AM; Department of Bioinformatics, Semmelweis University, Budapest, Hungary., Sanchez A; Section for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden., Kuras M; Clinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, Lund, Sweden.; Section for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden., Rodriguez Murillo J; Clinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, Lund, Sweden., Betancourt L; Section for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden., Domont GB; Proteomics Unit, Institute of Chemistry, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil., Semenov YR; Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Yu KH; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Kwon HJ; Chemical Genomics Global Research Lab, Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea., Németh IB; Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary., Fenyő D; Institute for Systems Genetics, NYU Grossman School of Medicine, New York City, New York, USA.; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York City, New York, USA., Wieslander E; Section for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden., Marko-Varga G; Clinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, Lund, Sweden.; Chemical Genomics Global Research Lab, Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.; 1st Department of Surgery, Tokyo Medical University, Tokyo, Japan., Gil J; Section for Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden.

Publikováno v: Clinical and translational medicine [Clin Transl Med] 2024 Jul; Vol. 14 (7), pp. e1773.