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A Large-Scale SNP-Based Genomic Admixture Analysis of the Captive Rhesus Macaque Colony at the California National Primate Research Center

Autor: N. W. Lerche, Cody T. Ross, Alex Kou, Sreetharan Kanthaswamy, David Glenn Smith, Paul Houghton, Jessica Satkoski Trask

Publikováno v: American Journal of Primatology. 74:747-757

Some breeding facilities in the United States have crossbred Chinese and Indian rhesus macaque (Macaca mulatta) founders either purposefully or inadvertently. Genetic variation that reflects geographic origins among research subjects has the potentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63325e7ad2235940712e20ec1bd2ac72
https://doi.org/10.1002/ajp.22025

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Synthetic peptides containing T and B cell epitopes from human immunodeficiency virus envelope gp120 induce anti-HIV proliferative responses and high titers of neutralizing antibodies in rhesus monkeys

Autor: M K Hart, T J Palker, T J Matthews, A J Langlois, N W Lerche, M E Martin, R M Scearce, C McDanal, D P Bolognesi, B F Haynes

Publikováno v: The Journal of Immunology. 145:2677-2685

We have previously described a synthetic peptide (T1-SP10) derived from two noncontiguous regions of HTLVIIIB envelope gp120 (T1, amino acids 428-443; SP10, amino acids 303-321) that induced type-specific anti-HIV neutralizing antibodies and T cell p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68b3a7be1640adb3eb3a26d4f05e7544
https://doi.org/10.4049/jimmunol.145.8.2677

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Mamu-DQA1 allele and genotype frequencies in a randomly sampled breeding colony of rhesus macaques (Macaca mulatta)

Autor: B K, Rolfs, J G, Lorenz, C C, Wu, N W, Lerche, D G, Smith

Publikováno v: Comparative medicine. 51(2)

We studied the allelic and genotypic distribution of the major histocompatibility class-II locus DQA1 observed in a random sample of Indian rhesus macaques (Macaca mulatta) from a major breeding facility in the United States. The DNA was isolated fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::68052b5c042cc49d9e443847e13ba656
https://pubmed.ncbi.nlm.nih.gov/11922180

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Eradication of simian retrovirus type D from a colony of cynomolgus, rhesus, and stump-tailed macaques by using serial testing and removal

Autor: M A, Schroder, S K, Fisk, N W, Lerche

Publikováno v: Contemporary topics in laboratory animal science. 39(4)

The markedly compromised health of animals in a macaque colony and the problematic interpretation of data from two drug safety assessment studies prompted a review of the effect of simian retrovirus type D on the drug-development process at a Midwest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3805b7f3f204907c873e28dc871e110f
https://pubmed.ncbi.nlm.nih.gov/11487224

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Effect of weaning time and associated management practices on postweaning chronic diarrhea in captive rhesus monkeys (Macaca mulatta)

Autor: C A, Muñoz-Zanzi, M C, Thurmond, D W, Hird, N W, Lerche

Publikováno v: Laboratory animal science. 49(6)

Our purpose was to assess the extent to which early weaning and other weaning-management factors affect development of postweaning chronic diarrhea in captive rhesus monkeys at the California Regional Primate Research Center between 1992 and 1995.Dat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::36c22622a2031738e3bb81e564889de3
https://pubmed.ncbi.nlm.nih.gov/10638496

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Cardiovascular, respiratory, thermoregulatory, sedative, and analgesic effects of intravenous administration of medetomidine in rhesus macaques (Macaca mulatta)

Autor: S V, Capuano, N W, Lerche, C R, Valverde

Publikováno v: Laboratory animal science. 49(5)

Medetomidine is a selective, specific, and potent alpha2-adrenergic receptor agonist that has been utilized successfully as a sedative/analgesic agent in a variety of domestic and nondomestic animals. The objective of this study was to document the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2876097ea5b7f754501e3edad569f8a0
https://pubmed.ncbi.nlm.nih.gov/10551456

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A simian model of human granulocytic ehrlichiosis

Autor: N W Lerche, Janet E Foley, J S Dumler, John E Madigan

Publikováno v: The American journal of tropical medicine and hygiene. 60(6)

Following intravenous inoculation with horse blood-infected with the agent of human granulocytic ehrlichiosis (HGE) from a human fatality, two rhesus macaques (Macaca mulatta) exhibited pyrexia and lethargy on days 4-12 postinfection (PI). Hematology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7f69303747982fe98b344f58e166b3
https://pubmed.ncbi.nlm.nih.gov/10403332

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