Zobrazeno 1 - 10
of 13
pro vyhledávání: '"N W, Toribara"'
Publikováno v:
Digestive diseases and sciences. 45(6)
Human mucin genes include membrane-bound mucins (MUC1, MUC3, MUC4) and secretory mucins (MUC2, MUC5AC, MUC5B, MUC6). Our aim was to determine mucin gene expression in human gallbladder cell lines, normal gallbladder from liver donors (N = 7) and surg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d31f6a77808b428f1102ef858250736
https://pubmed.ncbi.nlm.nih.gov/10877217
https://pubmed.ncbi.nlm.nih.gov/10877217
Autor:
A E, Bartman, M P, Buisine, J P, Aubert, G A, Niehans, N W, Toribara, Y S, Kim, E J, Kelly, J E, Crabtree, S B, Ho
Publikováno v:
The Journal of pathology. 186(4)
Secretory mucins play an important role in the cytoprotection of epithelial surfaces and are used as tumour markers in a variety of cancers. The MUC6 secretory mucin was originally isolated from a gastric cDNA library. The aim was to determine the sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb51e4a512bf58c55f98c684472693a2
https://pubmed.ncbi.nlm.nih.gov/10209489
https://pubmed.ncbi.nlm.nih.gov/10209489
Publikováno v:
The Journal of biological chemistry. 272(26)
The distribution of MUC6 suggests that its primary function is protection of vulnerable epithelial surfaces from damaging effects of constant exposure to a wide range of endogenous caustic or proteolytic agents. A combination of genomic, cDNA. and 3'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc5106d382d08bc748ce3ac0a8f5aa07
https://pubmed.ncbi.nlm.nih.gov/9195947
https://pubmed.ncbi.nlm.nih.gov/9195947
Autor:
I K, Gipson, S B, Ho, S J, Spurr-Michaud, A S, Tisdale, Q, Zhan, E, Torlakovic, J, Pudney, D J, Anderson, N W, Toribara, J A, Hill
Publikováno v:
Biology of reproduction. 56(4)
Recent characterizations of mucins at the molecular level indicate that at least eight mucin genes are expressed by epithelia of mucosal surfaces. The purpose of this study was to determine whether these cloned mucins, designated MUC1, MUC2, MUC3, MU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0493b228e201fd0c90bedb291e476ef7
https://pubmed.ncbi.nlm.nih.gov/9096884
https://pubmed.ncbi.nlm.nih.gov/9096884
Publikováno v:
Cancer research. 55(12)
Mucins synthesized by malignant cells may contribute (via decreased cellular adhesion and immune recognition) to cancer invasion and metastases. Human mucins are derived from a heterogeneous family of genes, labeled MUC1-6. Our aim was to determine t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f810b8e07ce455063a134224e657e646
https://pubmed.ncbi.nlm.nih.gov/7780985
https://pubmed.ncbi.nlm.nih.gov/7780985
Publikováno v:
The Journal of biological chemistry. 269(4)
Secretory mucins consist of a protein backbone that is catenated by disulfide bonds, heavily O-glycosylated, and packaged into storage granules prior to release from cells. In this paper, we identify and sequence cDNAs that encode the amino terminus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c23d45b7398dda66402e228b5b98d915
https://pubmed.ncbi.nlm.nih.gov/8300571
https://pubmed.ncbi.nlm.nih.gov/8300571
Autor:
N W, Toribara, A M, Roberton, S B, Ho, W L, Kuo, E, Gum, J W, Hicks, J R, Gum, J C, Byrd, B, Siddiki, Y S, Kim
Publikováno v:
The Journal of biological chemistry. 268(8)
Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma. In this paper we describe the isolation by expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29826b62ba0ea3f1b14f910fdc598176
https://pubmed.ncbi.nlm.nih.gov/7680650
https://pubmed.ncbi.nlm.nih.gov/7680650
Publikováno v:
The Journal of biological chemistry. 267(30)
The human MUC2 mucin is a large secretory glycoconjugate that coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Previous work has shown that this mucin contains an extended tandem repeat-containing domain ric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b389c27500533d34d81a2aa196ad67e
https://pubmed.ncbi.nlm.nih.gov/1400449
https://pubmed.ncbi.nlm.nih.gov/1400449
Autor:
J R, Gum, J W, Hicks, R E, Lagace, J C, Byrd, N W, Toribara, B, Siddiki, F J, Fearney, D T, Lamport, Y S, Kim
Publikováno v:
The Journal of biological chemistry. 266(33)
We have prepared antisera to deglycosylated rat intestinal mucin and used it to obtain immunoreactive clones from a rat jejunum cDNA library. Four of these clones were sequenced, and all were found to be partial cDNAs that contained 18-base pair tand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::789b27fc95dcb84f21ad8a90259f6458
https://pubmed.ncbi.nlm.nih.gov/1939280
https://pubmed.ncbi.nlm.nih.gov/1939280
Publikováno v:
Gastroenterology clinics of North America. 17(4)
Advances in the understanding of biochemical and molecular processes associated with cellular growth and differentiation, as well as colonic carcinogenesis hold promise for the development of new diagnostic and therapeutic modalities for this disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cbe9bb6d0ef4f7cd25c101de0a706e6c
https://pubmed.ncbi.nlm.nih.gov/3068143
https://pubmed.ncbi.nlm.nih.gov/3068143