Výsledky vyhledávání - "N Van Houten"

Antigen-Specific T Cell Activation and Proliferation During Oral Tolerance Induction

Autor: J, Sun, B, Dirden-Kramer, K, Ito, P B, Ernst, N, Van Houten

Publikováno v: The Journal of Immunology. 162:5868-5875

One of several routes of achieving immunologic tolerance is through functional inactivation of Ag-specific T cells. Oral administration of Ag can allow survival of the Ag-specific T cells that are functionally anergic. The aim of this study was to in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412c709e4ef796b25d85eef06c6a8e0d
https://doi.org/10.4049/jimmunol.162.10.5868

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The On-Orbit Performance of the Space Telescope Imaging Spectrograph

Autor: Dennis Ebbets, Mark D. Brumfield, R. Breyer, Stefi A. Baum, Mary Elizabeth Kaiser, P. R. Christon, S. I. Becker, Chuck Bowers, Randy A. Kimble, Sara R. Heap, R. J. Hill, Richard F. Green, Alan W. Delamere, L. W. Brown, S. Downey, Melissa A. McGrath, J. F. Grady, Richard D. Robinson, J. J. Yagelowich, D. Rose, A. Grusczak, David A. Dorn, C. Standley, A. Boggess, Vic S. Argabright, J. C. Blades, Anthony C. Danks, C. Ludtke, Stephen P. Maran, P. A. Driggers, Theodore R. Gull, J. G. Timothy, W. B. Fowler, W. Meyer, Mark Clampin, V. L. Krueger, M. N. Isaacs, J. A. Valenti, Wayne B. Landsman, George F. Hartig, J. J. Loiacono, Ralph C. Bohlin, Richard L. Bybee, R. Stocker, Fred L. Roesler, H. W. Moos, D. Hood, R. L. Lettieri, Eliot M. Malumuth, V. Balzano, C. Biagetti, Steven B. Kraemer, Henry C. Ferguson, David Michika, Robert S. Hill, R. Nyquist, Paul Goudfrooij, J. C. Hetlinger, M. Bottema, T. Wolfe, T. L. Beck, R. W. Melcher, Robert A. Woodruff, D. J. Lindler, Morley M. Blouke, Jennifer L. Sandoval, Lee Feinberg, F. J. Rebar, Charles L. Joseph, Nicholas R. Collins, C. N. Van Houten, J. F. Sullivan, J. K. Feggans, J. S. Gallegos, Carolyn A. Krebs, R. Doxsey, D. Weistrop, Stephen J. Hulbert, P. Plait, Bruce E. Woodgate, R. Kutina, R. H. Cornett, Jeffrey L. Linsky, R. Reed, H. Garner, H. D. Vitagliano, J. B. Hutchings, Edward B. Jenkins

Publikováno v: The Astrophysical Journal. 492:L83-L93

The Space Telescope Imaging Spectrograph (STIS) was successfully installed into the Hubble Space Telescope (HST) in 1997 February, during the second HST servicing mission, STS-82. STIS is a versatile spectrograph, covering the 115-1000 nm wavelength

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abd9acdfe7b7798553efb40976ba9639
https://doi.org/10.1086/311102

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Elevated expression of Bcl-2 and Bcl-x by intestinal intraepithelial lymphocytes: resistance to apoptosis by glucocorticoids and irradiation

Autor: Craig B. Thompson, D G Chilton, William K. Gourley, S F Blake, L H Boise, N Van Houten, E B Thompson, E J Li, T A Hallam

Publikováno v: International Immunology. 9:945-953

Administration of glucocorticoids or exposure to ionizing radiation in vivo results in a rapid cell death of thymocytes. We report that murine small intestinal intraepithelial lymphocytes (IEL) are resistant to both steroid- and radiation-induced del

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aca6e15df0af549369b756161e8ab6c
https://doi.org/10.1093/intimm/9.7.945

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CD16-expressing CD8alpha alpha+ T lymphocytes in the intestinal epithelium: possible precursors of Fc gammaR-CD8alpha alpha+ T cells

Autor: J She, S J Simpson, A Gupta, G Holländer, C Levelt, C P Liu, D Allen, N van Houten, B Wang, C Terhorst

Publikováno v: The Journal of Immunology. 158:4678-4687

T lymphocytes normally express their Ag receptors in association with the CD3 proteins, which include CD3zeta. In CD3zeta eta(null) mice thymic and peripheral T lymphocytes do not express the TCR/CD3 complex on their surface due to retention in the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4faf38367db861bdb4dcb70343585ab
https://doi.org/10.4049/jimmunol.158.10.4678

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Direct measurement of anergy of antigen-specific T cells following oral tolerance induction

Autor: N Van Houten, S F Blake

Publikováno v: The Journal of Immunology. 157:1337-1341

T cell tolerance induced by oral administration of Ag may be the result of either deletion or functional inactivation of Ag-specific T cells. OVA p(323-339)-specific TCR transgenic (Tg+) lymphocytes were transplanted into BALB/c recipients. Chimeric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::400a341f54091dfc4297ed4488032e56
https://doi.org/10.4049/jimmunol.157.4.1337

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CD2-CD4-CD8- lymph node T lymphocytes in MRL lpr/lpr mice are derived from a CD2+CD4+CD8+ thymic precursor

Autor: M M Landolfi, N Van Houten, J Q Russell, R Scollay, J R Parnes, R C Budd

Publikováno v: The Journal of Immunology. 151:1086-1096

MRL lpr/lpr (lymphoproliferative, lpr) mice demonstrate an age-dependent lymphoproliferation and development of autoimmunity. Characteristic of the lymphoproliferation in these mice is the accumulation of large numbers of CD4-CD8-(CD4-8-),CD3+ T lymp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51db6d55c547f3ec0adb06bb23804913
https://doi.org/10.4049/jimmunol.151.2.1086

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Accelerated programmed cell death of MRL-lpr/lpr T lymphocytes

Autor: N Van Houten, R C Budd

Publikováno v: The Journal of Immunology. 149:2513-2517

MRL-lpr/lpr (lpr) mice develop a polyclonal accumulation of abnormal peripheral T lymphocytes, which bear surface alpha beta TCR, CD3, and the B220 isoform of CD45, but lack CD4, CD8, and CD2. These T cells have a constitutively phosphorylated CD3 ze

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::13c947a4c6fc4217df66cf6a75d9588c
https://doi.org/10.4049/jimmunol.149.7.2513

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CD2 expression correlates with proliferative capacity of alpha beta + or gamma delta + CD4-CD8- T cells in lpr mice

Autor: R C Budd, J Q Russell, N van Houten, S M Cooper, H Yagita, J Wolfe

Publikováno v: The Journal of Immunology. 148:1055-1064

The T lymphocytes that accumulate in vast numbers in the lymphoid tissues of lpr/lpr (lpr) mice express a TCR-alpha beta that is polyclonally rearranged, and yet is devoid of surface CD4 or CD8 (CD4-8-) as well as CD2. lpr CD2- alpha beta + CD4-8- T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90ea7e8beeba2988cc1df77c8e8141c8
https://doi.org/10.4049/jimmunol.148.4.1055

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Selection of an attenuated Coxsackievirus B3 variant, using a monoclonal antibody reactive to myocyte antigen

Autor: Sally A. Huber, Albert Moraska, P E Bouchard, N Van Houten

Publikováno v: Journal of Virology. 65:1286-1290

Previously, we described a heart-reactive monoclonal antibody (MAb), 10A1, derived from a coxsackievirus B3 (CVB3)-infected mouse. This MAb selectively inhibits infection of HeLa cells and myocytes with the myocarditic virus variant (CVB3W). A plaque

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e395b6134dfa29b3976a344af25a6f
https://doi.org/10.1128/jvi.65.3.1286-1290.1991

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Simultaneously arising Ly-1(CD5) B cell lymphomas have identical expressed IgH and kappa-genes but different nonproductive heavy chain rearrangements

Autor: N Van Houten, G Haughton

Publikováno v: The Journal of Immunology. 144:745-751

A group of CD5(Ly-1) B cell lymphomas are described. They were derived from mice which received a common pool of syngeneic mouse spleen cells. Southern blot analysis revealed that the lymphomas exhibited an unusual set of Ig gene rearrangements. Six

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfd0cc1d735f47dd513879b5782015dd
https://doi.org/10.4049/jimmunol.144.2.745

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