Zobrazeno 1 - 10
of 10
pro vyhledávání: '"N V, Myshliakova"'
Publikováno v:
Bioorganicheskaia khimiia. 21(5)
In order to study the physiological functions of 11-deoxyprostaglandin E1-alpha, a series of its amide derivatives with amino acids and some amines were synthesized using mixed anhydride technique. The myotropic properties of newly synthesized compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7271273efc75d6afaff332864e5cf628
https://pubmed.ncbi.nlm.nih.gov/7661863
https://pubmed.ncbi.nlm.nih.gov/7661863
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 113(4)
Kinin-like properties of two new peptides NRP-11 and P7 which have structural similarity with neurotensin (NT) and kallidin (K) were investigated. It was found that, unlike NT and K, the new peptides possess reduced myotropic and hypotensive activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b665025fd66bf089db19520a76e957b9
https://pubmed.ncbi.nlm.nih.gov/1382694
https://pubmed.ncbi.nlm.nih.gov/1382694
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 113(2)
Biological properties of a novel vasopressin analogue were investigated. It was found that this analogue has no vasopressor and oxytocic activities but it exhibits a selective antidiuretic effect which is weaker than that of adiuretin (DDAVP). Novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8de0080010cf803eb7fe34b974874d4a
https://pubmed.ncbi.nlm.nih.gov/1611060
https://pubmed.ncbi.nlm.nih.gov/1611060
Autor:
F K, Mutulis, I E, Mutule, G Kh, Maurops, Iu, Bergmann, N V, Myshliakova, G M, Strazda, E E, Liepin'sh, Iu B, Saulitis, V D, Grigor'eva, Iu Iu, Balodis
Publikováno v:
Bioorganicheskaia khimiia. 17(10)
Cyclic analogues of substance P of the formula cyclo-[Glu-Phe-Phe-Gly-Leu-Met-NH(CH2)nNH-], where n = 3-10, 12, and open-chain analogues (XVIIIa, b) H-Glu.(NHR)-Phe-Phe-Gly-Leu-Met-NHR, where R = -CH3, -CH2CH2CH3, were synthesized. By NMR spectroscop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34c0f695f8f3672d0106e92173dd18db
https://pubmed.ncbi.nlm.nih.gov/1725106
https://pubmed.ncbi.nlm.nih.gov/1725106
Autor:
I E, Mutule, F K, Mutulis, N V, Myshliakova, M M, Veveris, V V, Golubeva, E A, Porunkevich, M P, Ratkevich, G M, Strazda, V E, Klusha, Iu, Bergmann
Publikováno v:
Bioorganicheskaia khimiia. 16(11)
1 alpha-beta-carboxypropionyl-cyclo(9----1 epsilon)-[Lys1, Gly6]bradykinin (Suc-c[Lys1, Gly6]B), 1 alpha-beta-carboxypropionyl-cyclo(10----1 epsilon)kallidin (Suc-cK), cyclo(10 gamma----1 epsilon)-[Glu10]kallidin (c[Glu10]K) and cyclo(11 gamma----1 e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a51234c67d491190d3dc2a6a9936cd21
https://pubmed.ncbi.nlm.nih.gov/1710895
https://pubmed.ncbi.nlm.nih.gov/1710895
Publikováno v:
Bioorganicheskaia khimiia. 16(3)
Five angiotensin cycloanalogues have been synthesised by classical methods of peptide chemistry, cyclisation being carried out via pentafluorophenyl esters. Cycloanalogues (I-IV) with a fixed potential turn in the C-terminal part of the angiotensin m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f1cfe8354e1d241f8c55e892d7f4ff2
https://pubmed.ncbi.nlm.nih.gov/2357239
https://pubmed.ncbi.nlm.nih.gov/2357239
Publikováno v:
Bioorganicheskaia khimiia. 13(12)
Two solution syntheses of cyclo(11----5 epsilon)-[Lys5]substance P-(5-11) (CLP) were carried out. The first synthesis involved the stepwise elongation of the peptide chain starting from glycine tert-butyl ester. At the stage of hexapeptide deprotecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d29204564dd27f12cbdd33a7c29d41f
https://pubmed.ncbi.nlm.nih.gov/2453193
https://pubmed.ncbi.nlm.nih.gov/2453193
Publikováno v:
Problemy endokrinologii. 22(3)
The authors studied comparatively the properties of two angiotensin II analogues, a new compound (1-hydantoin acid, 5-valine, 8-alanine)-angiotensin II (compound III) and (1-asparagine, 5-valine, 8-alanine)-angiotensin II (compound II), as of the myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1241929d2b3bcf137adb6338ba824147
https://pubmed.ncbi.nlm.nih.gov/935097
https://pubmed.ncbi.nlm.nih.gov/935097
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 96(11)
Cyclic analogs of bradykinin (CBK) and kallidin (CK) have a weak myotropic activity and a marked and prolonged hypotensive effect unlike linear bradykinin (BK) and kallidin (K) which produce a short-term hypotension and considerable contraction of ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::694e8f148bba6098f586f350c717eb4f
https://pubmed.ncbi.nlm.nih.gov/6315109
https://pubmed.ncbi.nlm.nih.gov/6315109
Publikováno v:
Bioorganicheskaia khimiia. 11(12)
New cyclic analogues of neurotensin (NT): [cyclo (13----8), Gly8]NT-(8-13), [cyclo (13----7), Gly7]NT-(7-13), [cyclo (13----5 epsilon), Lys5]NT-(5-13), [cyclo (13----4 epsilon), Lys4]NT-(4-13), and their linear precursors have been synthesized. The l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cf64ad86baf3a2ebb0468a054ec76d2
https://pubmed.ncbi.nlm.nih.gov/4084322
https://pubmed.ncbi.nlm.nih.gov/4084322