Výsledky vyhledávání - "N V, Lavrova"

Akademický článek

Urgent natural foci infections transmitted by ticks in Saint-Petersburg

Autor: V. V. Nechaev, A. A. Yakovlev, A. N. Uskov, L. E. Boburina, N. V. Lavrova, M. N. Pogromskaya, B. I. Aslanov, A. O. Shapar, S. V. Pavlenko, L. N. Pozhidaeva, A. K. Ivanov, A. I. Kravtsova, S. A. Leppik, E. I. Vitovich, M. I. Fedunyak

Publikováno v: Журнал инфектологии, Vol 10, Iss 4, Pp 104-115 (2018)

Purpose: to conduct a comparative analysis and to identify the epidemiological and clinical features of tick-borne encephalitis (TBE) and Lyme borreliosis as a mono- and coinfections in St. Petersburg. Materials and methods. 718 cases of TBE, 4353 ca

Externí odkaz: https://doaj.org/article/6f6a61e8832b46f6a25a5036882b4241

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Staphylococcus simulans recombinant lysostaphin: Production, purification, and determination of antistaphylococcal activity

Autor: N V Lavrova, Z. M. Galushkina, R S Ovchinnikov, Shaginian Ia, A V Demidenko, A. V. Grishin, M Iu Chernukha, Anna S. Karyagina, I. S. Boksha, Vladimir G. Lunin, L. R. Avetisian, A.M. Umyarov, A. M. Lyashchuk

Publikováno v: Biochemistry (Moscow). 81:502-510

Staphylococcus simulans lysostaphin is an endopeptidase lysing staphylococcus cell walls by cleaving pentaglycine cross-bridges in their peptidoglycan. A synthetic gene encoding S. simulans lysostaphin was cloned in Escherichia coli cells, and produc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46983115d6c2ef3c2fc2ee9a189a62f
https://doi.org/10.1134/s0006297916050072

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Disruption of bacterial biofilms using recombinant dispersin B

Autor: Tatyana N. Bolshakova, Z. M. Galushkina, Anna S. Karyagina, I. A. Shaginian, A. M. Lyashchuk, A. V. Grishin, O. Yu. Dobrynina, N V Lavrova, A.M. Umyarov, I. S. Boksha, L. R. Avetisian, M. Yu. Chernukha, Vladimir G. Lunin

Publikováno v: Microbiology. 84:498-501

A synthetic gene encoding dispersin B of Aggregatibacter actinomycetemcomitans was cloned and expressed in Escherichia coli cells. Procedure for purification of recombinant dispersin B was developed, and its in vitro activity was determined. The enzy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::063fdff99ad7059b07efe8903924d66e
https://doi.org/10.1134/s0026261715040062

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Fusion of Lysostaphin to an Albumin Binding Domain Prolongs Its Half-Life and Bactericidal Activity in the Systemic Circulation

Autor: N V Lavrova, Anna S. Karyagina, Maria S. Generalova, Vladimir G. Lunin, N. B. Polyakov, A. V. Grishin, Lyubov’ A. Soboleva, Nikita V. Shestak, A. M. Lyashchuk, N V Strukova, Z. M. Galushkina, Anna V. Ryazanova, I. S. Boksha, Liubov I. Popova

Publikováno v: Molecules
Volume 24
Issue 16
Molecules, Vol 24, Iss 16, p 2892 (2019)

Antibacterial lysins are promising proteins that are active against both antibiotic-susceptible and antibiotic-resistant bacterial strains. However, a major limitation of antibacterial lysins is their fast elimination from systemic circulation. PEGyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17dea016fd67218d04878e01e0e2aea
https://doi.org/10.3390/molecules24162892

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The Influence of Dimerization on the Pharmacokinetics and Activity of an Antibacterial Enzyme Lysostaphin

Autor: Anna S. Karyagina, Vladimir G. Lunin, N V Lavrova, Maria S. Generalova, Nikita V. Shestak, Vitaliy M Pavlov, Anna V. Ryazanova, Sergey S Vetchinin, N V Strukova, Z. M. Galushkina, A. V. Grishin, Lyubov’ A. Soboleva, I. S. Boksha, N. B. Polyakov, A. M. Lyashchuk

Publikováno v: Molecules, Vol 24, Iss 10, p 1879 (2019)
Molecules
Volume 24
Issue 10

The increasing prevalence of antibiotic-resistant strains of pathogenic bacteria is a major healthcare problem. Antibacterial lysins are enzymes that cleave the peptidoglycan of the bacterial cell wall. These proteins hold potential as a supplement o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33ec2d36593e5c48e297ed80916ed1e
https://doi.org/10.3390/molecules24101879

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Unique polymorphism of the CYP21A2 gene encoding 21-hydroxylase in female patients with the signs of hyperandrogenism

Autor: L. A. Ozolinya, I. A. Shilov, A. P. Barannik, L. I. Patrushev, A. A. Koltunova, N. V. Lavrova

Publikováno v: Russian Journal of Bioorganic Chemistry. 38:500-506

Hyperandrogenism is a pathological condition characterized by a high level of male sex hormones (andogens) in a female organism. One of the main causes of hyperandrogenism is the autosomal recessive disease, congenital adrenal hyperplasia (CAH). More

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fbd84e49a5e0e481f1bf9a8dd9a3f482
https://doi.org/10.1134/s1068162012050032

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Demetalization of red wines with chitinous adsorbents

Autor: N. V. Lavrova, A. N. Tumasjiev

Publikováno v: Russian Agricultural Sciences. 38:160-164

Different scientific and technical approaches (aspects) connected with the use of food chitin derived from shells of trade crayfish in stabilization of red wines against the stable turbidity due to the increased concentration of Fe and Cu in them and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99ee21c4ac32e240c7668613a2ee02a6
https://doi.org/10.3103/s1068367412020218

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Preparation and characterization of recombinant protein containing immunomimetic peptide of benzo(a)pyrene

Autor: M. V. Kostyanko, S. V. Apal’ko, Vladimir G. Lunin, N. V. Lavrova, A. V. Averjanov, A. M. Lyashchuk, V. A. Matveeva, Maksim L. Filipenko, E. A. Sherina, A. N. Glushkov

Publikováno v: Molecular Genetics, Microbiology and Virology. 26:74-81

Two recombinant plasmids were constructed. The first plasmid contained a hybrid gene composed of the sequences that encode immunomimetic peptide of benzo(a)pyrene, protein pIII of bacteriophage M13, and cellulose binding domain. The second plasmid co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b08dad13250da5cfc68c59a056254740
https://doi.org/10.3103/s0891416811020029

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Chimeric Lactase Capable of Spontaneous and Strong Immobilization on Cellulose and Development of a Continuous-Flow System for Lactose Hydrolysis at High Temperatures

Autor: N. A. Lunina, G. A. Velikodvorskaya, T. V. Tikhonova, I. D. Gurvits, Anna S. Karyagina, Vladimir G. Lunin, V. N. Tashlitskii, N. V. Lavrova, O. V. Sergienko

Publikováno v: Applied and Environmental Microbiology. 76:8071-8075

Recombinant plasmids containing fusion proteins composed of two different modules were constructed and expressed in Escherichia coli . The modules encoded the lactase LacA (LacZ) from the thermophilic bacterium Thermoanaerobacter ethanolicus and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a0b2783c9ae56bc90cbd9ef866dd64
https://doi.org/10.1128/aem.01517-10

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Production of the recombinant human bone morphogenetic protein-2 in Escherichia coli and testing of its biological activity in vitro and in vivo

Autor: A. E. Tukhvatulin, N. E. Sharapova, N. N. Poletaeva, A. V. Gromov, N. V. Lavrova, V. V. Zaitsev, Z. M. Galushkina, Anna S. Karyagina, Vladimir G. Lunin, O. V. Sergienko, L. A. Soboleva, A. S. Semikhin, Anna S. Ershova, A. P. Kotnova

Publikováno v: Molecular Biology. 44:923-930

Bone morphogenetic protein-2 (rhBMP-2) is an osteoinductive protein factor which plays a dominant role in growth and regeneration of bone tissue. In clinical practice, bone grafting materials on the basis of rhBMP-2 are widely applied; the Russian an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cc95904115fdd804633efd185f6d326
https://doi.org/10.1134/s0026893310060099

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