Zobrazeno 1 - 10
of 102
pro vyhledávání: '"N Tony Eissa"'
Autor:
Lisa J Martin, Jayanta Gupta, Soma S S K Jyothula, Melinda Butsch Kovacic, Jocelyn M Biagini Myers, Tia L Patterson, Mark B Ericksen, Hua He, Aaron M Gibson, Tesfaye M Baye, Sushil Amirisetty, Anna M Tsoras, Youbao Sha, N Tony Eissa, Gurjit K Khurana Hershey
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e33454 (2012)
Rationale and objectiveAutophagy is a cellular process directed at eliminating or recycling cellular proteins. Recently, the autophagy pathway has been implicated in immune dysfunction, the pathogenesis of inflammatory disorders, and response to vira
Externí odkaz:
https://doaj.org/article/387c3faf46704aaca8344c0be9ea39da
Autor:
Tesfaye M Baye, Melinda Butsch Kovacic, Jocelyn M Biagini Myers, Lisa J Martin, Mark Lindsey, Tia L Patterson, Hua He, Mark B Ericksen, Jayanta Gupta, Anna M Tsoras, Andrew Lindsley, Marc E Rothenberg, Marsha Wills-Karp, N Tony Eissa, Larry Borish, Gurjit K Khurana Hershey
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16522 (2011)
BackgroundCandidate gene case-control studies have identified several single nucleotide polymorphisms (SNPs) that are associated with asthma susceptibility. Most of these studies have been restricted to evaluations of specific SNPs within a single ge
Externí odkaz:
https://doaj.org/article/ccb79b07379a45bcbabd5246bbd0edd7
Autor:
Wei Li, Shu Zhu, Jianhua Li, Yan Huang, Rongrong Zhou, Xuegong Fan, Huan Yang, Xing Gong, N Tony Eissa, Willi Jahnen-Dechent, Ping Wang, Kevin J Tracey, Andrew E Sama, Haichao Wang
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16945 (2011)
A liver-derived protein, fetuin-A, was first purified from calf fetal serum in 1944, but its potential role in lethal systemic inflammation was previously unknown. This study aims to delineate the molecular mechanisms underlying the regulation of hep
Externí odkaz:
https://doaj.org/article/0cf8ecb180e94f77849c523bdb62ee67
Lymphangioleiomyomatosis (LAM) is a progressive cystic lung disease affecting some women with tuberous sclerosis complex (TSC). Sporadic LAM can develop in women without TSC, owing to somatic mutations in the TSC2 gene. Accumulating evidence supports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79e3aaf6c65a33a62672cd145398bddb
https://doi.org/10.1158/0008-5472.c.6505995
https://doi.org/10.1158/0008-5472.c.6505995
Increased phospho-Src in LAM lungs (Figure S1); Enhanced activation of Src, STAT3 and Snail in human LAM cells (Figure S2); mTOR activation in TSC2-deficient cells (Figure S3); Src kinase is activated in TSC2-deficient cells (Figure S4); Knockdown of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab71a542f2b66916c1421fb834270448
https://doi.org/10.1158/0008-5472.22402134.v1
https://doi.org/10.1158/0008-5472.22402134.v1
Autor:
Afshin, Ebrahimpour, Manisha, Ahir, Min, Wang, Anil G, Jegga, Mark D, Bonnen, N Tony, Eissa, Sydney B, Montesi, Ganesh, Raghu, Yohannes T, Ghebre
Publikováno v:
Scientific Reports. 12
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease of unknown etiology. Currently, pirfenidone and nintedanib are the only FDA-approved drugs for the treatment of IPF and are now the standard of care. This is a significant st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca88d78a869b88c57b6ad3ada432ff60
https://doi.org/10.1038/s41598-022-24985-x
https://doi.org/10.1038/s41598-022-24985-x
Publikováno v:
Molecular & Cellular Oncology, Vol 4, Iss 6 (2017)
TFEB is a master regulator for transcription of genes involved in autophagy, lysosome and mitochondrial biogenesis. Activity of TFEB is inhibited upon its phosphorylation. STUB1, a chaperone-dependent E3 ubiquitin ligase, modulates TFEB activity by p
Externí odkaz:
https://doaj.org/article/f018ee2c94df495c8d2cfd050a9adbdc
Publikováno v:
The Journal of Immunology. 207:661-670
Inflammation contributes to the pathogenesis and morbidity of wide spectrum of human diseases. The inflammatory response must be actively controlled to prevent bystander damage to tissues. Yet, the mechanisms controlling excessive inflammatory respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0808c04c346bd5ca13bc724ca274f6de
https://doi.org/10.4049/jimmunol.2000416
https://doi.org/10.4049/jimmunol.2000416
Autor:
Jin Wang, Subramanian Dhandayuthapani, Dekai Zhang, Chandrashekhar Pasare, Kishore Das, Chinnaswamy Jagannath, Jianjun Sun, Arshad Khan, Robert L. Hunter, Jaymie L. Estrella, Emily Soudani, Sankaralingam Saikolappan, Pearl Bakhru, Christopher R. Singh, N. Tony Eissa, Yue Ma
Publikováno v:
npj Vaccines, Vol 4, Iss 1, Pp 1-19 (2019)
NPJ Vaccines
NPJ Vaccines
Mycobacterium bovis BCG is widely used as a vaccine against tuberculosis due to M. tuberculosis (Mtb), which kills millions of people each year. BCG variably protects children, but not adults against tuberculosis. BCG evades phagosome maturation, aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5fd43a56e2e43f9e3c366b2d4ef373
http://link.springer.com/article/10.1038/s41541-019-0122-8
http://link.springer.com/article/10.1038/s41541-019-0122-8
Autor:
Lang Rao, N. Tony Eissa
Publikováno v:
Journal of Innate Immunity. 12:21-30
Autophagy is a major intracellular digestion system that delivers cytoplasmic components for degradation and recycling. In this capacity, autophagy plays an important role in maintaining cellular homeostasis by mediating the degradation of cellular m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb3152d1e2a44818502eca164dcbe49
https://doi.org/10.1159/000497414
https://doi.org/10.1159/000497414