Zobrazeno 1 - 10
of 60
pro vyhledávání: '"N Sumru Bayin"'
Autor:
Ryan T Willett, N Sumru Bayin, Andrew S Lee, Anjana Krishnamurthy, Alexandre Wojcinski, Zhimin Lao, Daniel Stephen, Alberto Rosello-Diez, Katherine L Dauber-Decker, Grant D Orvis, Zhuhao Wu, Marc Tessier-Lavigne, Alexandra L Joyner
Publikováno v:
eLife, Vol 8 (2019)
For neural systems to function effectively, the numbers of each cell type must be proportioned properly during development. We found that conditional knockout of the mouse homeobox genes En1 and En2 in the excitatory cerebellar nuclei neurons (eCN) l
Externí odkaz:
https://doaj.org/article/dac5953036a24d41a919545b03161f3f
Autor:
N Sumru Bayin, Alexandre Wojcinski, Aurelien Mourton, Hiromitsu Saito, Noboru Suzuki, Alexandra L Joyner
Publikováno v:
eLife, Vol 7 (2018)
Outside of the neurogenic niches of the brain, postmitotic neurons have not been found to undergo efficient regeneration. We demonstrate that mouse Purkinje cells (PCs), which are born at midgestation and are crucial for development and function of c
Externí odkaz:
https://doaj.org/article/0d3997780886410a8199e611bd72599a
Autor:
N Sumru Bayin, Aram S Modrek, August Dietrich, Jonathan Lebowitz, Tobias Abel, Hae-Ri Song, Markus Schober, David Zagzag, Christian J Buchholz, Moses V Chao, Dimitris G Placantonakis
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116114 (2014)
Glioblastoma multiforme (GBM) is a deadly primary brain malignancy. Glioblastoma stem cells (GSC), which have the ability to self-renew and differentiate into tumor lineages, are believed to cause tumor recurrence due to their resistance to current t
Externí odkaz:
https://doaj.org/article/28453f8fe62d44409f698e651ef8e9cb
Autor:
Reeti Mayur Sanghrajka, Richard Koche, Hector Medrano, Salsabiel El Nagar, Daniel N. Stephen, Zhimin Lao, N. Sumru Bayin, Kai Ge, Alexandra L. Joyner
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107831- (2023)
Summary: The major cause of treatment failure and mortality among medulloblastoma patients is metastasis intracranially or along the spinal cord. The molecular mechanisms driving tumor metastasis in Sonic hedgehog-driven medulloblastoma (SHH-MB) pati
Externí odkaz:
https://doaj.org/article/0ff602ca0cc44d9cb6da3c5af8918d2e
Autor:
Harikrishna Rallapalli, N. Sumru Bayin, Hannah Goldman, Dragan Maric, Brian J. Nieman, Alan P. Koretsky, Alexandra L. Joyner, Daniel H. Turnbull
Publikováno v:
NeuroImage, Vol 276, Iss , Pp 120198- (2023)
Magnetic Resonance Imaging (MRI) resolution continues to improve, making it important to understand the cellular basis for different MRI contrast mechanisms. Manganese-enhanced MRI (MEMRI) produces layer-specific contrast throughout the brain enablin
Externí odkaz:
https://doaj.org/article/f5291e0394464c1ea3b1b8d620ae031f
Publikováno v:
Cell. 186:1295-1299
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7c21ddef7f393801effdb8f41892ebb
https://doi.org/10.1016/j.cell.2023.03.002
https://doi.org/10.1016/j.cell.2023.03.002
Autor:
Alexandra L. Joyner, N. Sumru Bayin
Publikováno v:
Development (Cambridge, England). 149(18)
ABSRACT The cerebellum has a simple cytoarchitecture consisting of a folded cortex with three cell layers that surrounds a nuclear structure housing the output neurons. The excitatory neurons are generated from a unique progenitor zone, the rhombic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f083b6b7578e003afa0960ae37c8d44e
https://pubmed.ncbi.nlm.nih.gov/36172987
https://pubmed.ncbi.nlm.nih.gov/36172987
Publikováno v:
Frontiers in Molecular Neuroscience. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0261b7360ad7babe52632592bf8f5c18
https://doi.org/10.3389/fnmol.2022.1006888
https://doi.org/10.3389/fnmol.2022.1006888
Autor:
Ross Keller, Makiko Yamada, Daniel Cameron, Hiromichi Suzuki, Reeti Sanghrajka, Jake Vaynshteyn, Jeffrey Gerwin, Francesco Maura, William Hooper, Minita Shah, Nicolas Robine, Philip Demarest, N. Sumru Bayin, Luz Jubierre, Casie Reed, Michael D. Taylor, Alexandra L. Joyner, G. Praveen Raju, Alex Kentsis
Genomic rearrangements are a hallmark of most solid tumors, including medulloblastoma, one of the most common brain tumors in children. Childhood cancers involve dysregulated cell development, but their mutational causes remain largely unknown. One o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5f402393cd72cef69bf54a7c55ad609
https://doi.org/10.1101/2022.07.05.498128
https://doi.org/10.1101/2022.07.05.498128
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