Zobrazeno 1 - 10
of 31
pro vyhledávání: '"N Simon, Tchekmedyian"'
Autor:
Mary Hickman, Jessie Siau, Joseph Aisner, Henry Browder, F. Anthony Greco, N. Simon Tchekmedyian, James H. Keller
Publikováno v:
Cancer. 69:1268-1274
High-dose megestrol acetate has been associated with increased appetite and weight. To examine the effects of high-dose megestrol acetate in the treatment of anorexia and weight loss in patients with advanced hormone-insensitive malignant lesions, a
Autor:
N Simon, Tchekmedyian
Publikováno v:
Oncology (Williston Park, N.Y.). 29(8)
Publikováno v:
Clinical Drug Investigation. 26:593-601
Objective: This study set out to identify the resource use and time commitment associated with treatment of anaemia with erythropoietic therapy, for both haematology/oncology clinics and patients. Methods: The study was carried out at three haematolo
Publikováno v:
Clinical Lung Cancer. 6:170-174
The results of a retrospective exploratory analysis of a phase III trial of zoledronic acid in patients with bone metastases secondary to lung cancer or other solid tumors are reported herein to assess the risk of skeletal-related events (SREs) and t
Autor:
Sharon Yee, Randi Isaacs, Eric P. Lester, Eric Chevlen, Michael Ames, Thomas M. Beck, Jim H. Harvey, Howard D. Homesley, Stefan Madajewicz, Mary R. Creed, N. Simon Tchekmedyian, David Sciortino, Karen H. Crawford, William Whaley, Jesse I. Spector
Publikováno v:
The Oncologist. 3:432-438
Purpose: To compare the efficacy and safety of oral ondansetron with i.v. granisetron each given as a single dose prior to administration of highly emetogenic cisplatin chemotherapy. Patients and Methods: Chemotherapy-naive patients with histological
Autor:
Michael B. Jameson, William R. Wilson, Yongchuan Gu, Ramesh K. Ramanathan, N. Simon Tchekmedyian, Mark J. McKeage, Joseph G. Rajendran, Teresa J. Melink
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 496 (2012)
BMC Cancer
BMC Cancer
Background The purpose of this phase Ib clinical trial was to determine the maximum tolerated dose (MTD) of PR-104 a bioreductive pre-prodrug given in combination with gemcitabine or docetaxel in patients with advanced solid tumours. Methods PR-104 w
Publikováno v:
Cancer investigation. 28(8)
Baseline and disease progression characteristics may predict the risk of skeletal-related events (SREs) in patients with bone metastases from various solid tumors. Exploratory analysis of phase III trials compared zoledronic acid with placebo in pati
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 16:88S-92S
The endpoints used as outcome variables in clinical cancer treatment trials, including nutrition intervention studies, should contain items that are meaningful to the patient. Variables to consider are appetite, food intake, physical performance, psy
Publikováno v:
Supportive cancer therapy. 1(1)
Anemia is becoming recognized as a substantial problem for patients with cancer who are not receiving chemotherapy. Recently, darbepoetin alfa has been shown to provide significant clinical benefits in this patient population. This analysis assesses
Autor:
James P. Allison, Lawrence Fong, N. Simon Tchekmedyian, Israel Lowy, Eric J. Small, Brian I. Rini
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 13(6)
Purpose: Blockade of the T-cell inhibitory receptor CTL-associated antigen-4 (CTLA-4) augments and prolongs T-cell responses and is a strategy to elicit antitumor immunity. The objectives of this pilot study were to establish the pharmacokinetic and