Zobrazeno 1 - 10
of 569
pro vyhledávání: '"N Shepherd"'
Autor:
Trilok Neupane, Lydia R. Chambers, Alexander J. Godfrey, Melina M. Monlux, Evan J. Jacobs, Sophia Whitworth, Jamie E. Spawn, Seo Hee K. Clingman, Kathleen L. Vergunst, Fair M. Niven, James J. Townley, Iris W. Orion, Carly R. Goodspeed, Kathryn A. Cooper, Jeff D. Cronk, Jennifer N. Shepherd, David N. Langelaan
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-13 (2022)
The RquA protein is required for rhodoquinone biosynthesis; however, its exact function is not yet known. Here, the authors demonstrate that RquA is homologous to SAM-dependent methyltransferases but functions as an aminotransferase using Mn2+ as cof
Externí odkaz:
https://doaj.org/article/b2e554daf1fb49c2b8306775749eb555
Autor:
June H Tan, Margot Lautens, Laura Romanelli-Cedrez, Jianbin Wang, Michael R Schertzberg, Samantha R Reinl, Richard E Davis, Jennifer N Shepherd, Andrew G Fraser, Gustavo Salinas
Publikováno v:
eLife, Vol 9 (2020)
Parasitic helminths use two benzoquinones as electron carriers in the electron transport chain. In normoxia, they use ubiquinone (UQ), but in anaerobic conditions inside the host, they require rhodoquinone (RQ) and greatly increase RQ levels. We prev
Externí odkaz:
https://doaj.org/article/c592d7ec0d4e4dfcb49e098736479870
Autor:
Adérito L Monjane, Simon Dellicour, Penelope Hartnady, Kehinde A Oyeniran, Betty E Owor, Marion Bezuidenhout, Daphné Linderme, Rizwan A Syed, Lara Donaldson, Shane Murray, Edward P Rybicki, Anders Kvarnheden, Elham Yazdkhasti, Pierre Lefeuvre, Rémy Froissart, Philippe Roumagnac, Dionne N Shepherd, Gordon W Harkins, Marc A Suchard, Philippe Lemey, Arvind Varsani, Darren P Martin
Publikováno v:
eLife, Vol 9 (2020)
For pathogens infecting single host species evolutionary trade-offs have previously been demonstrated between pathogen-induced mortality rates and transmission rates. It remains unclear, however, how such trade-offs impact sub-lethal pathogen-inflict
Externí odkaz:
https://doaj.org/article/28baa327e21a451f849d2a0fa0052410
Autor:
Amanda R M Campbell, Benjamin R Titus, Madeline R Kuenzi, Fernando Rodriguez-Perez, Alysha D L Brunsch, Monica M Schroll, Matthew C Owen, Jeff D Cronk, Kirk R Anders, Jennifer N Shepherd
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217281 (2019)
The lipophilic electron-transport cofactor rhodoquinone (RQ) facilitates anaerobic metabolism in a variety of bacteria and selected eukaryotic organisms in hypoxic environments. We have shown that an intact rquA gene in Rhodospirillum rubrum is requi
Externí odkaz:
https://doaj.org/article/9c4047d86fb743b7bf606157e44e8c82
Autor:
Courtney W Stairs, Laura Eme, Sergio A Muñoz-Gómez, Alejandro Cohen, Graham Dellaire, Jennifer N Shepherd, James P Fawcett, Andrew J Roger
Publikováno v:
eLife, Vol 7 (2018)
Under hypoxic conditions, some organisms use an electron transport chain consisting of only complex I and II (CII) to generate the proton gradient essential for ATP production. In these cases, CII functions as a fumarate reductase that accepts electr
Externí odkaz:
https://doaj.org/article/7df347d0d28a4aebb1dcd9bd1626fe87
Akademický článek
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Autor:
Andrzej A. Romaniuk, Alexandra N. Shepherd, David V. Clarke, Alison J. Sheridan, Sheena Fraser, László Bartosiewicz, Jeremy S. Herman
Publikováno v:
Royal Society Open Science, Vol 3, Iss 10 (2016)
Rodents have important effects on contemporary human societies, sometimes providing a source of food but more often as agricultural pests, or as vectors and reservoirs of disease. Skeletal remains of rodents are commonly found in archaeological assem
Externí odkaz:
https://doaj.org/article/b1555600f0664ad088d806c013ce330c
Autor:
Richard G. Brown, A Kendrick, John Stradling, J Pepperell, A Woroszyl, B Gray, B Marsh, N Bryan, J Sexton, J Appleby, Alison McMillan, Brendan G Cooper, Annabel H. Nickol, A Gaspar, N Shepherd, S Wright, A Cooper, J Stockley, C Rogers, Chris D. Turnbull, Joerg Steier, G Hill, J Davidson, J Page, Timothy G. Quinnell, H Farley, M Allen, C Gillooly, G Gibbons, Sophie West
Publikováno v:
Stay awake! It’s an update on sleep.
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1863:148695
Akademický článek
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