Zobrazeno 1 - 10
of 179
pro vyhledávání: '"N Schaeren-Wiemers"'
Autor:
K Saravanan, N Schaeren-Wiemers, D Klein, R Sandhoff, A Schwarz, A Yaghootfam, V Gieselmann, S Franken
Publikováno v:
Neurobiology of Disease, Vol 16, Iss 2, Pp 396-406 (2004)
Metachromatic leukodystrophy (MLD) is a lysosomal lipid storage disease caused by arylsulfatase A deficiency. In MLD patients the sphingolipid sulfatide increasingly accumulates leading to progressive demyelination. We have analysed arylsulfatase A-d
Externí odkaz:
https://doaj.org/article/fddcd4ae7a9a45d596579510d1dcb123
Akademický článek
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Akademický článek
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Publikováno v:
International MS journal. 15(2)
Recently, the introduction of RNA profiling using microarray technology has helped to elucidate gene expression changes in diseased tissue samples from postmortem human brains. Especially, in the field of multiple sclerosis (MS) research, microarray-
Autor:
N, Schaeren-Wiemers
Publikováno v:
Praxis. 94(6)
Publikováno v:
Journal of neurocytology. 31(1)
The functional importance of the basal lamina in Schwann cell development and in adult peripheral nerve fibers is well known. We have demonstrated previously by confocal microscopy that IgM deposits are present on the basal lamina of myelinating Schw
Publikováno v:
Journal of neurochemistry. 82(3)
The myelin and lymphocyte protein (MAL) proteolipid is localized in central and peripheral compact myelin membranes, as well as in apical membranes of particular polarized cells. In this study, we addressed the question whether MAL and other peripher
Autor:
A J, Steck, N, Schaeren-Wiemers
Publikováno v:
Schweizerische medizinische Wochenschrift. 129(46)
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system. It results from an autoimmune response against one of several antigens of cerebral white matter tissue. The pathogenesis of MS lesions consists in migrati
Publikováno v:
Development (Cambridge, England). 124(6)
The expression pattern of the serine protease inhibitor gene Protease nexin-1 (PN-1) has been analyzed by in situ hybridization during embryonic nervous system develop-ment. PN-1 was found to be specifically expressed at the junction between the mes-
Autor:
M. Empl, A. Straube, Andreas J. Steck, Susanne Renaud, Peter Fuhr, N. Schaeren-Wiemers, Beat Erne
Publikováno v:
Pain Practice. 1:379-380
The objective of this study was to determine whether the cytokine tumor necrosis factor α (TNF-α) acts as a pain mediator in neuropathic pain in humans. Patients with painful neuropathies showed a stronger TNF-α immunoreactivity in myelinating Sch