Zobrazeno 1 - 10
of 36
pro vyhledávání: '"N S, Magnuson"'
Publikováno v:
Annals of the New York Academy of Sciences. 129:521-528
Publikováno v:
The Journal of Immunology. 156:549-557
We have studied pim-1 proto-oncogene expression in human T cell responses to Ag receptor-generated signals. The pim-1 gene encodes a serine/threonine protein kinase that is expressed primarily in cells of hematopoietic lineage and is implicated in th
Publikováno v:
Endocrinology. 136:5252-5259
The lactogen-dependent Nb2 lymphoma line (Nb2-11) represents a useful pre-T cell model for investigation of early molecular events coupled to PRL-stimulated cell cycle progression. Expression of pim-1, a protooncogene that encodes a conserved cytosol
Publikováno v:
The Journal of Immunology. 147:3653-3659
mRNA expression of the serine/threonine kinase protooncogene Pim-1 was investigated in mitogen-treated normal bovine lymphocytes. After stimulation with Con A and phorbol ester (PMA), normal bovine PBMC exhibited a 3.5-fold induction of pim-1 mRNA wi
Publikováno v:
The Journal of Immunology. 144:691-698
The effect of cyclosporin A on the continuous proliferation of Theileria parva-infected T cells was tested and compared with its effect on the Con A-induced proliferation of bovine lymph node cells. The effect of rIL-2 on cyclosporin A-treated cells
Publikováno v:
Endocrinology. 140(12)
The lactogen-dependent rat Nb2 lymphoma is a useful model to investigate PRL signaling pathways that lead to regulation of gene transcription. A primary mechanism coupled to PRL receptor (PRLR) activation in Nb2 cells involves phosphorylation by Jak-
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 8(12)
Expression of Pim-1, an oncogenic serine/threonine kinase, is highly regulated at the transcriptional, posttranscriptional, and posttranslational levels. Here, we report that expression of Pim-1 kinase is additionally regulated at the translational l
Publikováno v:
Anticancer research. 17(2A)
The in vitro effects of conjugated dienoic derivatives of linoleic acid (CLA) in combination with beta-carotene on lymphocyte and macrophage function was studied. Porcine blood lymphocytes and murine peritoneal macrophages were incubated with 0 (cont
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 7(12)
Whereas Nb2-11 lymphoma cells critically require prolactin (PRL) for growth, Nb2-SFJCD1 subline cells are growth factor independent. Treatment with the differentiating agent, sodium butyrate (NaBT), has been demonstrated previously to lead to growth
Publikováno v:
Leukemia. 10(10)
Bovine leukemia virus (BLV) induces a non-malignant, polyclonal, persistent lymphocytosis (PL) of circulating, CD5 B lymphocytes in cattle, with variable progression to CD5 B cell leukemia or lymphoma. We analyzed the expression of two proto-oncogene