Zobrazeno 1 - 9
of 9
pro vyhledávání: '"N S, Lanko"'
Publikováno v:
Voprosy onkologii. 43(3)
C3HA female mice received 0.1-0.3 mg/g body weight diethylstilbestrol (DES) on day 17 of gestation. Their descendants received a total of 20 injections of 1.2-dimethylhydrazine (DMH), subcutaneously, weekly, starting from month 2. Prenatal DES signif
Publikováno v:
Teratogenesis, carcinogenesis, and mutagenesis. 17(1)
C3HA and CBA female mice received a single intraperitoneal (i.p.) injection of 0.1 or 0.3 mg/kg body weight (b.w.) of diethylstilbestrol (DES) at day 17 of pregnancy. The descendants, starting from the age of 2-3 months, were receiving weekly subcuta
Publikováno v:
Eksperimental'naia onkologiia. 12(3)
The results of experiments on the 1,2-dimethylhydrazine (DMH) induction of epithelial renal tumours in CBA male mice are presented. The dose-response study shows a sharp increase (from 5 to 75%) of the epithelial renal tumour incidence in the range o
Autor:
V. S. Turusov, N. S. Lanko
Publikováno v:
Bulletin of Experimental Biology and Medicine. 88:757-759
Pararenal angiosarcoma developed in 42% of CBA male mice injected subcutaneously 1.2-dimethyl hydrazine (DMH) in a dose of 8 mg/kg body weight within 30 weeks. None of 176 CBA female mice given the same treatment developed such tumors. Histologically
Publikováno v:
Cancer research. 48(8)
To study the effect of deuterium substitution on the carcinogenicity of 1,2-dimethylhydrazine (DMH) in mice, two comparisons were made between DMH and its fully methyl-deuterated analogue, [2H6]DMH. In a lifetime study with the CBA strain, groups of
Autor:
V S, Turusov, N S, Lanko
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 88(7)
Pararenal angiosarcoma developed in 42% of CBA male mice injected subcutaneously 1.2-dimethyl hydrazine (DMH) in a dose of 8 mg/kg body weight within 30 weeks. None of 176 CBA female mice given the same treatment developed such tumors. Histologically
Publikováno v:
Voprosy onkologii. 29(5)
Effects of route of administration (subcutaneous, intraperitoneal, by stomach tube and with drinking water) and dose fractionation on the carcinogenicity of 1,2-dimethylhydrazine (DMH) were studied in CBA and (C57B1/6j X CBA)F1 mice. Fractionation of
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 92(12)
1,2-Dimethylhydrazine was administered subcutaneously in a dose of 8 mg/kg bw to 2-, 8- and 12-month-old female CBA mice for 25 weeks. The animals were serially killed 26-35 weeks after the beginning of treatment. The incidence of colon tumors in 2-m
Publikováno v:
Voprosy onkologii. 23(7)
Female CBA mice were treated weekly with subcutaneous injections of 1,2-dimethyl-hydrazine (8 mg/Kg b. w.) for 38--40 weeks. All animals but one developed tumors, mainly of the uterus, and region and intestine. Uterine tumors were most likely endomet