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Discovery of selective, small-molecule inhibitors of RNA complexes--I. The Tat protein/TAR RNA complexes required for HIV-1 transcription

Autor: H Y, Mei, D P, Mack, A A, Galan, N S, Halim, A, Heldsinger, J A, Loo, D W, Moreland, K A, Sannes-Lowery, L, Sharmeen, H N, Truong, A W, Czarnik

Publikováno v: Bioorganicmedicinal chemistry. 5(6)

We have developed a therapeutic program focusing on the inhibition of a human immunodeficiency virus-1 specific protein-RNA interaction. This program begins with a search for small organic molecules that would interfere with the binding of Tat protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::44ced896f35a95030f8637dffade5456
https://pubmed.ncbi.nlm.nih.gov/9222511

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