Zobrazeno 1 - 10
of 153
pro vyhledávání: '"N Ruggieri"'
Autor:
J. R. Hagemann, L. Lembke-Jene, F. Lamy, M.-E. Vorrath, J. Kaiser, J. Müller, H. W. Arz, J. Hefter, A. Jaeschke, N. Ruggieri, R. Tiedemann
Publikováno v:
Climate of the Past, Vol 19, Pp 1825-1845 (2023)
As remnants of living organisms, alkenones and isoprenoid glycerol dialkyl glycerol tetraether lipids (isoGDGTs) are widely used biomarkers for determining ocean water temperatures from the past. The organisms that these proxy carriers stem from are
Externí odkaz:
https://doaj.org/article/a430df6da0424d08a18aed689791a62d
Autor:
Michael Brandon Ware, Maggie Phillips, Christopher McQuinn, Mohammad Y. Zaidi, Hannah M. Knochelmann, Emily Greene, Brian Robinson, Cameron J. Herting, Thomas A. Mace, Zhengjia Chen, Chao Zhang, Matthew R. Farren, Amanda N. Ruggieri, Jacob S. Bowers, Reena Shakya, Alton B. Farris, Gregory Young, William E. Carson III, Bassel El-Rayes, Chrystal M. Paulos, Gregory B. Lesinski
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
This study aimed to enhance antitumor immune responses to pancreatic cancer via Ab-based blockade of IL-6 and cytotoxic T-lymphocyte–associated protein 4 (CTLA-4). Mice bearing s.c. or orthotopic pancreatic tumors were treated with blocking Abs to
Externí odkaz:
https://doaj.org/article/c9e661e36d174f30b84405ca8e2d56e4
Autor:
Amanda N. Ruggieri, Mark Yarchoan, Subir Goyal, Yuan Liu, Elad Sharon, Helen X. Chen, Brian M. Olson, Chrystal M. Paulos, Bassel F. El-Rayes, Shishir K. Maithel, Nilofer S. Azad, Gregory B. Lesinski
Publikováno v:
Clin Cancer Res
Purpose: Biliary tract cancers (BTC) are aggressive malignancies refractory to chemotherapy and immunotherapy. MEK inhibition (MEKi)-based regimens may have utility in this disease when combined with PD-L1 blockade. We hypothesize that dual MEK/PD-L1
Autor:
Gregory B. Lesinski, Bassel F. El-Rayes, Shishir K. Maithel, Rafi Ahmed, Juan M. Sarmiento, Zhengjia Chen, Chao Zhang, Ganji Purnachandra Nagaraju, Matthew R. Farren, Hannah Komar, Brian M. Olson, Amanda N. Ruggieri, Mohammad Y. Zaidi, Michael B. Ware, Yuchen Zhang
Supplemental Figures S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334b97489ab6bc6ce4b453fc89989db7
https://doi.org/10.1158/1535-7163.22521040
https://doi.org/10.1158/1535-7163.22521040
Autor:
Gregory B. Lesinski, Bassel F. El-Rayes, Shishir K. Maithel, Rafi Ahmed, Juan M. Sarmiento, Zhengjia Chen, Chao Zhang, Ganji Purnachandra Nagaraju, Matthew R. Farren, Hannah Komar, Brian M. Olson, Amanda N. Ruggieri, Mohammad Y. Zaidi, Michael B. Ware, Yuchen Zhang
Pancreatic ductal adenocarcinoma (PDAC) has a prominent fibrotic stroma, which is a result of interactions between tumor, immune and pancreatic stellate cells (PSC), or cancer-associated fibroblasts (CAF). Targeting inflammatory pathways present with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230926bfbd23653fd8c0df4dc849af8a
https://doi.org/10.1158/1535-7163.c.6542881
https://doi.org/10.1158/1535-7163.c.6542881
Autor:
Gregory B. Lesinski, Nilofer S. Azad, Shishir K. Maithel, Bassel F. El-Rayes, Chrystal M. Paulos, Brian M. Olson, Helen X. Chen, Elad Sharon, Yuan Liu, Subir Goyal, Mark Yarchoan, Amanda N. Ruggieri
Supplementary Table from Combined MEK/PD-L1 Inhibition Alters Peripheral Cytokines and Lymphocyte Populations Correlating with Improved Clinical Outcomes in Advanced Biliary Tract Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6fdaa8375934267afa17540e47cb54
https://doi.org/10.1158/1078-0432.22489040.v1
https://doi.org/10.1158/1078-0432.22489040.v1
Autor:
F Nisi, L Carenzo, N Ruggieri, A Reda, MG Pascucci, A Pignataro, E Civilini, F Piccioni, E Giustiniano
Publikováno v:
Seminars in Vascular Surgery.
Autor:
Gregory B. Lesinski, Nilofer S. Azad, Shishir K. Maithel, Bassel F. El-Rayes, Chrystal M. Paulos, Brian M. Olson, Helen X. Chen, Elad Sharon, Yuan Liu, Subir Goyal, Mark Yarchoan, Amanda N. Ruggieri
Supplementary Figure from Combined MEK/PD-L1 Inhibition Alters Peripheral Cytokines and Lymphocyte Populations Correlating with Improved Clinical Outcomes in Advanced Biliary Tract Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cecfc87f138a87dee7bbc1f2f58e7c5
https://doi.org/10.1158/1078-0432.22489058.v1
https://doi.org/10.1158/1078-0432.22489058.v1
Autor:
Gregory B. Lesinski, Nilofer S. Azad, Shishir K. Maithel, Bassel F. El-Rayes, Chrystal M. Paulos, Brian M. Olson, Helen X. Chen, Elad Sharon, Yuan Liu, Subir Goyal, Mark Yarchoan, Amanda N. Ruggieri
Purpose:Biliary tract cancers (BTC) are aggressive malignancies refractory to chemotherapy and immunotherapy. MEK inhibition (MEKi)-based regimens may have utility in this disease when combined with PD-L1 blockade. We hypothesize that dual MEK/PD-L1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c89dc9e1ce8787b709cae8b46666f72
https://doi.org/10.1158/1078-0432.c.6532868.v1
https://doi.org/10.1158/1078-0432.c.6532868.v1
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