Community acceptability to antimalarial mass drug administrations in Magude district, Southern Mozambique: A mixed methods study.

Autor: Beatriz Galatas, Hoticha Nhantumbo, Rodolfo Soares, Helder Djive, Ilda Murato, Wilson Simone, Eusebio Macete, N Regina Rabinovich, Pedro Alonso, Baltazar Candrinho, Francisco Saúte, Pedro Aide, Khátia Munguambe

Publikováno v: PLoS ONE, Vol 16, Iss 3, p e0249080 (2021)

BackgroundThis study aimed to capture the acceptability prior to, during and after the implementation of the first year of MDA rounds conducted under the Magude project, a malaria elimination project in southern Mozambique.MethodsThis was a mixed-met

Externí odkaz: https://doaj.org/article/45e68513a12344ae9319ce9996237c31

Safety of oral ivermectin during pregnancy: a systematic review and meta-analysis

Autor: Patricia Nicolas, MSc, Marta F Maia, PhD, Quique Bassat, ProfPhD, Kevin C Kobylinski, PhD, Wuelton Monteiro, PhD, N Regina Rabinovich, MD, Clara Menéndez, ProfPhD, Azucena Bardají, PhD, Carlos Chaccour, PhD

Publikováno v: The Lancet Global Health, Vol 8, Iss 1, Pp e92-e100 (2020)

Summary: Background: About 3·7 billion doses of ivermectin have been distributed in mass drug administration (MDA) campaigns globally over the past 30 years. At 10–100 times higher than current human doses, ivermectin is a known teratogen in mamma

Externí odkaz: https://doaj.org/article/ca03b4cd34954265baf63864706656b2

BOHEMIA: Broad One Health Endectocide-based Malaria Intervention in Africa-a phase III cluster-randomized, open-label, clinical trial to study the safety and efficacy of ivermectin mass drug administration to reduce malaria transmission in two African settings

Autor: Carlos Chaccour, Aina Casellas, Felix Hammann, Paula Ruiz-Castillo, Patricia Nicolas, Julia Montaña, Mary Mael, Prashant Selvaraj, Urs Duthaler, Sigilbert Mrema, Mwaka Kakolwa, Issa Lyimo, Fredros Okumu, Achla Marathe, Roger Schürch, Eldo Elobolobo, Charfudin Sacoor, Francisco Saute, Kang Xia, Caroline Jones, Cassidy Rist, Marta Maia, N. Regina Rabinovich

Publikováno v: Chaccour, Carlos; Casellas, Aina; Hammann, Felix; Ruiz-Castillo, Paula; Nicolas, Patricia; Montaña, Julia; Mael, Mary; Selvaraj, Prashant; Duthaler, Urs; Mrema, Sigilbert; Kakolwa, Mwaka; Lyimo, Issa; Okumu, Fredros; Marathe, Achla; Schürch, Roger; Elobolobo, Eldo; Sacoor, Charfudin; Saute, Francisco; Xia, Kang; Jones, Caroline; ... (2023). BOHEMIA: Broad One Health Endectocide-based Malaria Intervention in Africa-a phase III cluster-randomized, open-label, clinical trial to study the safety and efficacy of ivermectin mass drug administration to reduce malaria transmission in two African settings. Trials, 24(1), p. 128. BioMed Central 10.1186/s13063-023-07098-2

Background Residual malaria transmission is the result of adaptive mosquito behavior that allows malaria vectors to thrive and sustain transmission in the presence of good access to bed nets or insecticide residual spraying. These behaviors include c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb472b8e3d44f035aae53fed791046d

The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: A pilot, double-blind, placebo-controlled, randomized clinical trial

Autor: Belén Sádaba, Mariano Rodríguez-Mateos, Carlota Jordán-Iborra, Carlos Chaccour, Alejandro Fernández-Montero, Gabriel Reina, Andrés Blanco-Di Matteo, Felix Hammann, Jose Yuste, Mirian Fernández-Alonso, Gemma Moncunill, Iñigo Pineda, Joe Brew, Aina Casellas, Ester Laso, Verena Schöning, Paula Ruiz-Castillo, Juan C. Gabaldon-Figueira, Mary-Ann Richardson, José Luis del Pozo, Francisco Carmona-Torre, Carlota Dobaño, N. Regina Rabinovich, Miriam Giráldez

Publikováno v: EClinicalMedicine
EClinicalMedicine, Vol 32, Iss, Pp 100720-(2021)
Chaccour, Carlos; Casellas, Aina; Blanco-Di Matteo, Andrés; Pineda, Iñigo; Fernandez-Montero, Alejandro; Ruiz-Castillo, Paula; Richardson, Mary-Ann; Rodríguez-Mateos, Mariano; Jordán-Iborra, Carlota; Brew, Joe; Carmona-Torre, Francisco; Giráldez, Miriam; Laso, Ester; Gabaldón-Figueira, Juan C; Dobaño, Carlota; Moncunill, Gemma; Yuste, José R; Del Pozo, Jose L; Rabinovich, N Regina; Schöning, Verena; ... (2021). The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: A pilot, double-blind, placebo-controlled, randomized clinical trial. EClinicalMedicine, 32, p. 100720. Elsevier 10.1016/j.eclinm.2020.100720

Background Ivermectin inhibits the replication of SARS-CoV-2 in vitro at concentrations not readily achievable with currently approved doses. There is limited evidence to support its clinical use in COVID-19 patients. We conducted a Pilot, randomized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5b86812fbfa9ee09a97ff9f46c58a0

A Roadmap for the Development of Ivermectin as a Complementary Malaria Vector Control Tool

Autor: Peter, Billingsley, Fred, Binka, Carlos, Chaccour, Brian, Foy, Silvia, Gold, Matiana, Gonzalez-Silva, Julie, Jacobson, George, Jagoe, Caroline, Jones, Patrick, Kachur, Kevin, Kobylinski, Anna, Last, James V, Lavery, David, Mabey, David, Mboera, Charles, Mbogo, Ana, Mendez-Lopez, N. Regina, Rabinovich, Sarah, Rees, Frank, Richards, Cassidy, Rist, Jessica, Rockwood, Paula, Ruiz-Castillo, Jetsumon, Sattabongkot, Francisco, Saute, Hannah, Slater, Andrew, Steer, Kang, Xia, Rose, Zullinger

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
The American Journal of Tropical Medicine and Hygiene

In the context of stalling progress against malaria, resistance of mosquitoes to insecticides, and residual transmission, mass drug administration (MDA) of ivermectin, an endectocide used for neglected tropical diseases (NTDs), has emerged as a promi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32867e77dd81d9eff90354e528951b1
http://hdl.handle.net/2445/150450