Zobrazeno 1 - 10
of 15
pro vyhledávání: '"N R, Mason"'
Autor:
B D, Gitter, R F, Bruns, J J, Howbert, D C, Waters, P G, Threlkeld, L M, Cox, J A, Nixon, K L, Lobb, N R, Mason, P W, Stengel
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 275(2)
LY303870 [(R)-1-[N-(2-methoxybenzyl)acetylamino]-3-(1H-indol-3-yl)-2-[N-(2-(4- (piperidin-1-yl)piperidin-1-yl)acetyl)amino]propane] is a new, potent and selective nonpeptide neurokinin-1 (NK-1) receptor antagonist. LY303870 bound selectively and with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c5c0e91e949c65a5596c944f83cb07b
https://pubmed.ncbi.nlm.nih.gov/7473161
https://pubmed.ncbi.nlm.nih.gov/7473161
Publikováno v:
Research communications in chemical pathology and pharmacology. 77(2)
A series of imipramine analogs were tested for inhibition of [3H]-MK801 binding and for their ability to protect against NMDA-induced lethality in mice. The structure-activity relationship (SAR) for the inhibition of [3H]-MK801 binding found primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ba9088db24ebb0ffdea908901675b36
https://pubmed.ncbi.nlm.nih.gov/1439188
https://pubmed.ncbi.nlm.nih.gov/1439188
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 256(2)
The cholecystokinin (CCK) receptor involved in contraction of guinea pig ileal longitudinal muscle to cholecystokinin is poorly understood; some studies have suggested that contraction was mediated via a CCK-A receptor whereas other studies have impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7cce4c34fbe6e06a04ca41011f94f39
https://pubmed.ncbi.nlm.nih.gov/1704435
https://pubmed.ncbi.nlm.nih.gov/1704435
Publikováno v:
Biology of Reproduction. 28:134-141
A potent prostaglandin synthesis inhibitor (cyclooxygenase inhibitor), 2(p-biphenyl) propionic acid (BPPA), was administered subcutaneously at the dose of 1 mg twice daily to pseudopregnant and cyclic rats. It was found to prolong the duration of pse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd4b56211e863fd8aeaa3cd093dd7d1
https://doi.org/10.1095/biolreprod28.1.134
https://doi.org/10.1095/biolreprod28.1.134
Autor:
R W, Fuller, N R, Mason
Publikováno v:
Research communications in chemical pathology and pharmacology. 54(1)
Flumezapine, 7-fluoro-2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3- b] [1,5]benzodiazepine, antagonized the increases in serum corticosterone concentration caused by a serotonin agonist, quipazine, and by a dopamine agonist, pergolide, in rats.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9495fa5c6d581d674ed0e3108281162a
https://pubmed.ncbi.nlm.nih.gov/2879325
https://pubmed.ncbi.nlm.nih.gov/2879325
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 235(2)
LY53857 is an ergoline derivative that is a potent and selective antagonist at 5-HT2 receptors. The present study investigated the activities of the diastereomers of LY53857. The SS- and RR-isomers and the meso mixture of isomers of LY53857 all showe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb45f7a68eb743d71aa13c66adadf43c
https://pubmed.ncbi.nlm.nih.gov/4057073
https://pubmed.ncbi.nlm.nih.gov/4057073
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 218(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21852e8d5e35fed90f4a2d3a78a1596a
https://pubmed.ncbi.nlm.nih.gov/6167711
https://pubmed.ncbi.nlm.nih.gov/6167711
Structure-activity relationships in the actions of 1-phenyl-piperazines on brain serotonin receptors
Autor:
R W, Fuller, N R, Mason
Publikováno v:
Advances in experimental medicine and biology. 133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ec6973816a578b3b15d496e48778521
https://pubmed.ncbi.nlm.nih.gov/6172017
https://pubmed.ncbi.nlm.nih.gov/6172017
Autor:
M L, Cohen, R W, Fuller, K D, Kurz, C J, Parli, N R, Mason, D B, Meyers, J K, Smallwood, R E, Toomey
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 244(1)
The preclinical pharmacologic activity of LY281067 shows it to be a potent and highly selective serotonergic (5-HT2) receptor antagonist. Based upon binding studies with 5-HT2 receptors in brain cortical membranes and block of 5-HT-induced contractio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::794674610401477fdf9ae14a1a2eb32d
https://pubmed.ncbi.nlm.nih.gov/3335993
https://pubmed.ncbi.nlm.nih.gov/3335993
Publikováno v:
Research communications in chemical pathology and pharmacology. 51(1)
1-(1-Naphthyl)piperazine (1-NP) had high affinity for tritiated serotonin, tritiated LSD (lysergic acid diethylamide) and tritiated spiperone binding sites in rat brain cortex in vitro. 1-NP at doses of 3-30 mg/kg i.p. decreased 5-hydroxyindoleacetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a75dc19c1faf32c5dab0571efac9f55b
https://pubmed.ncbi.nlm.nih.gov/2419952
https://pubmed.ncbi.nlm.nih.gov/2419952