Zobrazeno 1 - 10
of 45
pro vyhledávání: '"N R, Cozzarelli"'
Autor:
Steven A. Wasserman, N R Cozzarelli
Publikováno v:
Journal of Biological Chemistry. 266:20567-20573
The mechanism by which the type 2 topoisomerase from bacteriophage T4 mediates knotting of negatively supercoiled DNA was deduced from an analysis of product topology. The knotted products were nicked and then subjected to electrophoresis in order to
Autor:
A I, Alexandrov, N R, Cozzarelli, V F, Holmes, A B, Khodursky, B J, Peter, L, Postow, V, Rybenkov, A V, Vologodskii
Publikováno v:
Genetica. 106(1-2)
This article is a perspective on the separation of the complementary strands of DNA during replication. Given the challenges of DNA strand separation and its vital importance, it is not surprising that cells have developed many strategies for promoti
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 21(10)
DNA replication requires the unwinding of the parental duplex, which generates (+) supercoiling ahead of the replication fork. It has been thought that removal of these (+) supercoils was the only method of unlinking the parental strands. Recent evid
Publikováno v:
Cell. 98(2)
Xenopus 13S condensin converts interphase chromatin into mitotic-like chromosomes, and, in the presence of ATP and a type I topoisomerase, introduces (+) supercoils into DNA. The specific production of (+) trefoil knots in the presence of condensin a
Autor:
N R, Cozzarelli, K R, Fulton
Publikováno v:
Proceedings of the National Academy of Sciences. 93
Autor:
E L Zechiedrich, N R Cozzarelli
Publikováno v:
Genesdevelopment. 9(22)
For a cell to complete DNA replication, every link between the Watson-Crick strands must be removed by topoisomerases. Previously, we reported that the inhibition of topoisomerase IV (topo IV) leads to the accumulation of catenated plasmid replicons
Publikováno v:
Journal of molecular biology. 243(3)
The Gin recombinase of phage Mu selectively mediates DNA inversion between two inversely oriented recombination sites (gix) and requires the assistance of three accessory factors: negative supercoiling, an enhancer sequence, and the protein Fis. Dele
Autor:
P, Dröge, N R, Cozzarelli
Publikováno v:
Methods in enzymology. 212
Autor:
S A, Wasserman, N R, Cozzarelli
Publikováno v:
The Journal of biological chemistry. 266(30)
The mechanism by which the type 2 topoisomerase from bacteriophage T4 mediates knotting of negatively supercoiled DNA was deduced from an analysis of product topology. The knotted products were nicked and then subjected to electrophoresis in order to
Publikováno v:
The Journal of biological chemistry. 266(4)
To determine the physiologically important features of site-specific recombination by Escherichia coli Tn3 resolvase we analyzed the salient properties of the reaction in vivo. A two-plasmid system in which one plasmid served as substrate while the o