Zobrazeno 1 - 10
of 41
pro vyhledávání: '"N P Vermeulen"'
Publikováno v:
Endocrine Connections, Vol 8, Iss 1, Pp 1-7 (2023)
Purpose: Total elbow arthroplasty (TEA) is rarely performed compared to other arthroplasties. For many surgical procedures, literature shows better outcomes when they are performed by experienced surgeons and in so-called ‘high-volume’ hospitals.
Externí odkaz:
https://doaj.org/article/09e1c6cc37aa4e8d8696655e7d4399ee
Publikováno v:
Advances in experimental medicine and biology. 500
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fced0e4357c4a61eb6bda3c845089d5
https://pubmed.ncbi.nlm.nih.gov/11764919
https://pubmed.ncbi.nlm.nih.gov/11764919
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(3)
Midazolam is almost exclusively metabolized by cytochrome P450 3A (CYP3A) isoenzymes. Therefore, midazolam is used as a probe to determine CYP3A levels in humans and rats. A prerequisite for longitudinal determination of CYP3A expression levels using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2e3f3be406365de25e08a40a886bbdc
https://pubmed.ncbi.nlm.nih.gov/11714877
https://pubmed.ncbi.nlm.nih.gov/11714877
Publikováno v:
Biochemical pharmacology. 60(10)
The study of drug metabolism in cultured rat hepatocytes is hampered by the rapid loss of the expression of cytochrome P450 enzymes. Nevertheless, the activity of cytochrome P450 3A (CYP3A), one of the most important isoenzymes for drug metabolism, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4ce1ca98b10215709644393f8a90fe1
https://pubmed.ncbi.nlm.nih.gov/11020454
https://pubmed.ncbi.nlm.nih.gov/11020454
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 294(2)
Selenocysteine Se-conjugates have recently been proposed as potential prodrugs to target pharmacologically active selenol compounds to the kidney. Although rat renal cytosol displayed a high activity of beta-elimination activity toward these substrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2420ebaff7138fb55eac55d19b792b1c
https://pubmed.ncbi.nlm.nih.gov/10900257
https://pubmed.ncbi.nlm.nih.gov/10900257
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 294(2)
This study was performed to evaluate whether selenocysteine Se-conjugates are substrates for human cysteine conjugate beta-lyase enzymes. By testing kidney cytosols of three different humans, we studied interindividual differences in beta-lyase enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a8353965b318b3c9b7f28e1c267fe6d
https://pubmed.ncbi.nlm.nih.gov/10900258
https://pubmed.ncbi.nlm.nih.gov/10900258
Publikováno v:
Free radical biologymedicine. 26(1-2)
Free radical damage is an important factor in many pathological and toxicological processes. Despite extensive research efforts in biomarkers in recent years, yielding promising results in experimental animals, there is still a great need for additio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38f9d88affeda2af9eb4bf4cef4061e5
https://pubmed.ncbi.nlm.nih.gov/9890655
https://pubmed.ncbi.nlm.nih.gov/9890655
Publikováno v:
Journal of computer-aided molecular design. 12(2)
Geometry optimizations for several spin states of the iron(III)-S-methyl- porphyrin complex, the iron (III)-oxo-S-methyl-porphyrin complex and the respective anions were performed in order to examine models for intermediates in the oxidative cycle of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4a4d64e75016f94b428552625167ae5
https://pubmed.ncbi.nlm.nih.gov/9690176
https://pubmed.ncbi.nlm.nih.gov/9690176
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 26(5)
In this study the disposition of 1,2-[14C]dibromoethane (1, 2-[14C]DBE) was investigated in male Wistar rats. 1,2-DBE is a cytotoxic and carcinogenic compound that has been used as an additive in leaded gasoline and as a fumigant. 1,2-[14C]DBE was ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01e8eb001ce8167ff9cd4e692cf5fce2
https://pubmed.ncbi.nlm.nih.gov/9571225
https://pubmed.ncbi.nlm.nih.gov/9571225
Autor:
L W, Wormhoudt, J N, Commandeur, J H, Ploemen, R S, Abdoelgafoer, A, Makansi, P J, Van Bladeren, N P, Vermeulen
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(4)
1,2-Dibromoethane (1,2-DBE) is a carcinogenic compound that is metabolized both by cytochrome P450 (P450) and glutathione S-transferase (GST) enzymes, and that has been used by us as a model compound to study interindividual variability in biotransfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aaaa1e23f2446feaa34e690ff5c0dec5
https://pubmed.ncbi.nlm.nih.gov/9107551
https://pubmed.ncbi.nlm.nih.gov/9107551