Zobrazeno 1 - 10
of 51
pro vyhledávání: '"N P Higgins"'
Autor:
Ariane Toussaint, N. Patrick Higgins
Publikováno v:
Viruses, Vol 15, Iss 3, p 637 (2023)
For 20 years, the intricacies in bacteriophage Mu replication and its regulation were elucidated in collaboration between Ariane Toussaint and her co-workers in the Laboratory of Genetics at the Université Libre de Bruxelles, and the groups of Marti
Externí odkaz:
https://doaj.org/article/dc2b3a9e3259493888baffc0808131b7
Publikováno v:
Microorganisms, Vol 7, Iss 3, p 81 (2019)
Prokaryotes have an essential gene—gyrase—that catalyzes negative supercoiling of plasmid and chromosomal DNA. Negative supercoils influence DNA replication, transcription, homologous recombination, site-specific recombination, genetic transposit
Externí odkaz:
https://doaj.org/article/fde0b2cafeac4953b36d878730af57b8
Autor:
N. C. Higgins, Mitchell R. P. LaPointe
Publikováno v:
SAGE Open, Vol 2 (2012)
Attributing a negative achievement outcome (e.g., failing a test) to causes that are personally uncontrollable and stable elicits a low expectancy of future success, feelings of hopelessness in that domain, and reduced behavioral efforts to succeed.
Externí odkaz:
https://doaj.org/article/b93b9939ef6d48b8a60091bdaf4e4a45
Publikováno v:
PLoS Genetics, Vol 8, Iss 8, p e1002845 (2012)
Gyrase catalyzes negative supercoiling of DNA in an ATP-dependent reaction that helps condense bacterial chromosomes into a compact interwound "nucleoid." The supercoil density (σ) of prokaryotic DNA occurs in two forms. Diffusible supercoil density
Externí odkaz:
https://doaj.org/article/65eced27329b4eee94f6f6e666e5bb3c
Autor:
F Rijsdjik, Cathy MacLean, John R.W. Yates, Michelle Clifford, J N P Higgins, K le Maréchal, Patrick Bolton, Ayla Humphrey, Brian G. R. Neville, Charlotte Tye
Publikováno v:
Psychological medicine. 45(11)
BackgroundTuberous sclerosis complex (TSC) is associated with intellectual disability, but the risk pathways are poorly understood.MethodThe Tuberous Sclerosis 2000 Study is a prospective longitudinal study of the natural history of TSC. One hundred
Publikováno v:
The Journal of Laryngology & Otology. 119:479-482
Mycotic aneurysm of the petrous temporal bone is extremely rare, with only 12 cases previously reported. We review the literature to date and present a case of petrositis complicated by a mycotic aneurysm of the internal carotid artery, which was man
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 75:621-625
Background: Venous sinus disease must be excluded before diagnosing idiopathic intracranial hypertension but is found only rarely in typical cases. Magnetic resonance venography (MRV) is the technique of choice for investigating this, and provides im
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 74:1662-1666
Background: The high pressures documented in the intracranial venous sinuses in idiopathic intracranial hypertension (IIH) could be the result of focal stenotic lesions in the lateral sinuses obstructing cranial venous outflow. Objective: To explore
Autor:
N P Higgins, K E Scheirer
Publikováno v:
Journal of Biological Chemistry. 272:27202-27209
The potent synthetic fluoroquinolones and the natural CcdB protein encoded by the F plasmid both inhibit bacterial growth by attacking DNA gyrase and by stimulating enzyme-induced breaks in bacterial DNA. The cleavage mechanisms of these structurally
Autor:
J N P Higgins, John D. Pickard
Publikováno v:
British journal of neurosurgery. 27(6)
A 47 year old man developed severe headaches after resection of an acoustic neuroma ipsilateral to non dominant venous drainage. CSF pressures were normal but imaging studies showed acquired, severe narrowing of the sigmoid sinus where it traversed t