Zobrazeno 1 - 10
of 26
pro vyhledávání: '"N P, Milyutina"'
Publikováno v:
Neuroscience and Behavioral Physiology. 51:1073-1078
To study correlations between oxidative stress (OS) and clinical changes in patients with neurodegenerative Parkinson's and to identify clinical/biochemical subtypes of the disease.One hundred and nine people were studied, including 91 patients with
Autor:
I. F. Shlyk, V. V. Vnukov, N. S. Doltmurzieva, A. A. Plotnikov, N. P. Milyutina, R. V. Sidorov, A. A. Ananyan, D. Yu. Gvaldin, D. Yu. Pospelov
Publikováno v:
Advances in Gerontology. 9:426-433
To study the role of paraoxonase, myeloperoxidase, arginase, asymmetric dimethylarginine, and nitric oxide in the mechanisms of the pathogenesis of postpericardiotomy syndrome (PPCS), 76 patients with ischemic heart disease (IHD) who underwent corona
Publikováno v:
Clinical Medicine (Russian Journal). 96:60-65
Joint injury is a well-established risk factor for development of post-traumatic knee osteoarthritis (PTOA) and may lead to joint inflammation. The aims of the study were: the investigation of proinflammatory mediators - the levels of IL-1β and uric
Autor:
S. B. Panina, V. V. Vnukov, A. A. Plotnikov, I. V. Kornienko, O. I. Gutsenko, A. A. Ananyan, N. P. Milyutina
Publikováno v:
Biochemistry (Moscow). 82:942-952
The administration of SkQ1 to rats at the dose of 50 nmol/kg for five days significantly increased the mRNA levels of transcription factor Nrf2 and of Nrf2-controlled genes encoding antioxidant enzymes SOD1, SOD2, CAT, and GPx4, whereas changes in th
Autor:
M. A. Zabrodin, A. A. Ananyan, S. B. Panina, N. P. Milyutina, A. A. Plotnikov, V. V. Vnukov, I. V. Krolevets
Publikováno v:
Russian Journal of Genetics: Applied Research. 7:197-202
Traumas are among the leading risk factors for the development of osteoarthritis of the knee (OA). The aim of the present work was to study the associations between polymorphisms in the nNOS and eNOS genes and the risk of the development of post-trau
Autor:
A. A. Ananyan, D. Yu. Pospelov, Roman V. Sidorov, N. P. Milyutina, D. Yu. Gvaldin, V. V. Vnukov, V. N. Shchetko
Publikováno v:
Clinical Medicine (Russian Journal). 94:827-831
The purpose of this research was the clinical biochemical study of the role of the antioxidant system, products of lipid peroxidation and proinflammatory mediators in the mechanisms of development of postpericardiotomy syndrome. 50 patients who under
Autor:
V. V. Vnukov, D. Yu. Gvaldin, N. P. Milyutina, A. A. Plotnikov, I. V. Kornienko, O. I. Gutsenko, A. A. Ananyan, S. B. Panina
Publikováno v:
Biochemistry. Biokhimiia. 83(10)
Here, we studied the effect of the mitochondria-targeted antioxidant SkQ1 (plastoquinone cationic derivative) on the CASP3 gene expression and caspase-3 activity in rat cerebral cortex and brain mitochondria under normal conditions and in oxidative s
Autor:
A. A. Plotnikov, I. V. Krolevets, A. A. Ananyan, N. P. Milyutina, M. A. Zabrodin, V. V. Vnukov, S. B. Panina
Publikováno v:
Экологическая генетика, Vol 13, Iss 3, Pp 15-22 (2015)
Background. Knee osteoarthritis (OA) is a common chronic degenerative disease. The risk factors for the development of knee OA are joint trauma and genetic predisposition. The aim of the present work was to study the associations between gene polymor
Autor:
Svetlana Demyanenko, L. V. Gutnikova, A. A. Alexandrova, V. N. Prokof'ev, Vladimir A. Chistyakov, E. V. Mashkina, V. A. Serezhenkov, N. P. Milyutina
Publikováno v:
Biochemistry (Moscow). 75:1383-1387
Introduction of the plastoquinone derivative 10-(6'-plastoquinonyl)decyltriphenylphosphonium (SkQ1) into male Wistar rats once a day for two weeks in doses of 25 and 250 nmol/kg led to elevation of 17β-estradiol level in blood serum by 33 and 41%, r
Publikováno v:
Bulletin of experimental biology and medicine. 161(1)
Analysis of polymorphisms of genes encoding antioxidant enzymes SOD1 (G7958A), SOD2 (T58C), CAT (C-262T), and GSTP1 (Ile105Val) in 93 patients with post-traumatic gonarthrosis showed that GSTP1 Ile105Val polymorphism is often associated with heterozy