Zobrazeno 1 - 10 of 32 pro vyhledávání: '"N Nagvekar"'
1
Approaches for Studying the Pathogenic T Cells in Autoimmune Patients
Autor: Leslie Jacobson, Anne Marie Moody, F. Baggi, John Newsom-Davis, Gillian Harcourt, Hidenori Matsuo, Nick Willcox, B. Ong, David Beeson, Anna Paola Batocchi, N. Pantic, Angela Vincent, N. Nagvekar, M. Nicolle, Simon Hawke
Publikováno v: Annals of the New York Academy of Sciences. 681:219-237
Our provisional conclusions from this work are as follows. (1) For screening responses of established lines, native human AChR is not prohibitively scarce, especially if it is concentrated onto beads, and class II-transfected TE671 cells may be usefu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b9ab9b0dee1fd6d887271e82778bde
https://doi.org/10.1111/j.1749-6632.1993.tb22888.x
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3
A pathogenetic role for the thymoma in myasthenia gravis. Autosensitization of IL-4- producing T cell clones recognizing extracellular acetylcholine receptor epitopes presented by minority class II isotypes
Autor: Nick Willcox, David Beeson, Ioannis Roxanis, Moss P, John Curnow, N Pantic, N Nagvekar, A Vincent, John Newsom-Davis, A M Moody
Publikováno v: Scopus-Elsevier
Myasthenia gravis (MG) is caused by helper T cell-dependent autoantibodies against the muscle acetylcholine receptor (AChR). Thymic epithelial tumors (thymomas) occur in 10% of MG patients, but their autoimmunizing potential is unclear. They express
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e5e75ca25ab8017bbf1b6dee972f73
https://pubmed.ncbi.nlm.nih.gov/9593783
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4
Epitopes expressed in myasthenia gravis (MG) thymomas are not recognized by patients' T cells or autoantibodies
Autor: Angela Vincent, Nick Willcox, N Nagvekar, Leslie Jacobson
SUMMARYMost thymic epithelial tumours that associate with MG express an epitope that resembles the sequence α373–380 from the cytoplasmic loop of the acetylcholine receptor (AChR). It has been proposed that sensitization to this linear epitope ini
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f73f3cc376b4f7ac9bc8189c1de2c6f
https://europepmc.org/articles/PMC1904952/
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6
Oncogene proteins and proliferation antigens in thymomas: increased expression of epidermal growth factor receptor and Ki67 antigen
Autor: N E Gilhus, K C Gatter, J Newsom-Davis, N Willcox, Helen Turley, Margaret Jones, N Nagvekar
Publikováno v: Journal of clinical pathology. 48(5)
AIMS--To examine thymomas for proteins encoded by oncogenes and to determine whether their presence correlates with tumour growth and associated myasthenia gravis. METHODS--Sections of 24 thymomas were incubated with anti-EGF receptor (EGF-R), anti-K
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1572777c94a295f973ecb5504872f4
https://pubmed.ncbi.nlm.nih.gov/7629292
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