Zobrazeno 1 - 10
of 109
pro vyhledávání: '"N N, Osborne"'
Autor:
N. N. Osborne, K.-G. Schmidt
Publikováno v:
Der Ophthalmologe. 101:1087-1092
Nach Schatzung der WHO sind etwa 105 Millionen Menschen weltweit vom Glaukom betroffen. Das Glaukom kann als progressive Optikoneuropathie mit struktureller Schadigung des Sehnervenkopfs und Untergang retinaler Ganglienzellen definiert werden. Obwohl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df96fa297596df11bf24775775b0e05a
https://doi.org/10.1007/s00347-004-1129-7
https://doi.org/10.1007/s00347-004-1129-7
Autor:
G. Chidlow, N. N. Osborne
Publikováno v:
Journal of Neural Transmission. 104:1015-1025
Physiological studies have shown that serotonin and 5-HT1A agonists can influence muscarinic function in the rabbit iris-ciliary body (ICB). The purpose of this study was to examine whether a direct interaction exists between muscarinic and 5-HT1A re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0e362e51c5dc7545d28e2a115af658
https://doi.org/10.1007/bf01273315
https://doi.org/10.1007/bf01273315
Autor:
N N Osborne, G Chidlow
Publikováno v:
Ophthalmologica. 210:308-314
Serotonin 5-HT1A-type and beta-adrenergic receptors have similar molecular characteristics, which explains why certain substances like propranolol have affinities for both receptor types. Activation of 5-HT1A receptors leads to a decrease in intracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4009d961a1d247c0c3663a5db3a055b1
https://doi.org/10.1159/000310730
https://doi.org/10.1159/000310730
Publikováno v:
Neurochemistry International, 53(6-8), 325-337. PERGAMON-ELSEVIER SCIENCE LTD
The purpose of the present Study was to determine whether the flavonoid, baicalin is effective at blunting the negative influence of ischemia/reperfusion to the rat retina ill situ and of various insults to a transformed retinal ganglion cells (RGC-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9abbbb674b5d626c0ef2b1c755fb2cec
https://pubmed.ncbi.nlm.nih.gov/18835309
https://pubmed.ncbi.nlm.nih.gov/18835309
Publikováno v:
Journal of Neurophysiology. 63:1413-1425
1. We have used pharmacologic, immunologic, and biochemical techniques to examine the role of neurochemicals in modulating the myogenic heart of the snail, Lymnaea. 2. 5-HT [high-pressure liquid chromatography (HPLC) and immunocytochemistry], dopamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef9e6b52944e56a16ccd54ae47216fe
https://doi.org/10.1152/jn.1990.63.6.1413
https://doi.org/10.1152/jn.1990.63.6.1413
Publikováno v:
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft. 101(11)
In hypoxic or ischemic states, the receptors of the ganglion cells are overstimulated by release of neurotransmitters. Glutamate and GABA (gamma-aminobutyric acid) are the decisive neurotransmitters in the retina. It is presumed that the extent of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4a87ca25175efedcfc0f0c34cee393c
https://pubmed.ncbi.nlm.nih.gov/15490183
https://pubmed.ncbi.nlm.nih.gov/15490183
Autor:
N N, Osborne, K-G, Schmidt
Publikováno v:
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft. 101(11)
According to estimates made by WHO, approximately 105 million people are affected worldwide by glaucoma. This can be defined as progressive optic neuropathy with structural damage of the optic nerve head and death of retinal ganglion cells. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cbd63baa1e32cde9486d1483685c45dc
https://pubmed.ncbi.nlm.nih.gov/15490185
https://pubmed.ncbi.nlm.nih.gov/15490185
Autor:
J P, Wood, N N, Osborne
Publikováno v:
Archives of ophthalmology (Chicago, Ill. : 1960). 119(1)
To investigate the role of extracellular zinc on the death process of cultured human retinal pigment epithelial (RPE) cells.Confluent cells on borosilicate glass coverslips were treated with substances in serum-free growth medium for various times an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01d254b54f983647585a24dc2dd83b37
https://pubmed.ncbi.nlm.nih.gov/11146730
https://pubmed.ncbi.nlm.nih.gov/11146730
Autor:
J, Melena, N N, Osborne
Publikováno v:
Archivos de la Sociedad Espanola de Oftalmologia. 75(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9d64168968dfd057adabd34814c4e13
https://pubmed.ncbi.nlm.nih.gov/11151100
https://pubmed.ncbi.nlm.nih.gov/11151100
Autor:
M S, Nash, N N, Osborne
Publikováno v:
Investigative ophthalmologyvisual science. 40(6)
Thy-1 is primarily, if not entirely, expressed by the ganglion cells within the retina. This knowledge was used to index ganglion cell death after ischemia and excitotoxicity by studying changes in Thy-1 mRNA levels.Insults to the rat retina were del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94ca5007adc76c6aa36f4a3dfd02ecff
https://pubmed.ncbi.nlm.nih.gov/10235569
https://pubmed.ncbi.nlm.nih.gov/10235569