Zobrazeno 1 - 10
of 2 439
pro vyhledávání: '"N Myers"'
Autor:
Alice Zhao, Laura Maple, Juwei Jiang, Katie N. Myers, Callum G. Jones, Hannah Gagg, Connor McGarrity-Cottrell, Ola Rominiyi, Spencer J. Collis, Greg Wells, Marufur Rahman, Sarah J. Danson, Darren Robinson, Carl Smythe, Chun Guo
Publikováno v:
Cell Death and Disease, Vol 15, Iss 12, Pp 1-14 (2024)
Abstract SUMOylation, the covalent attachment of the small ubiquitin-like modifier (SUMO) to target proteins, and its reversal, deSUMOylation by SUMO proteases like Sentrin-specific proteases (SENPs), are crucial for initiating cellular responses to
Externí odkaz:
https://doaj.org/article/0162534f7f4e46afa780e89c9a03b231
Autor:
Madison N. Myers, Miguel Chirivi, Jeff C. Gandy, Joseph Tam, Maya Zachut, G. Andres Contreras
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background As cows transition from pregnancy to lactation, free fatty acids (FFA) are mobilized from adipose tissues (AT) through lipolysis to counter energy deficits. In clinically healthy cows, lipolysis intensity is reduced throughout lac
Externí odkaz:
https://doaj.org/article/7170c60b05b84d02a9ac12ebb4a5d5a9
Publikováno v:
Biogeosciences, Vol 21, Pp 3093-3120 (2024)
Large, high-severity wildfires in many regions across the globe have increased concerns about their impacts on carbon cycling in watersheds. Altered sources of carbon and changes in catchment hydrology after wildfire can lead to shifts in dissolved o
Externí odkaz:
https://doaj.org/article/f9f7f40a0e1646648fe6d30057dd2d7a
Autor:
Akanksha Srivastava, Graciela M. Nogueras-Gonzalez, Yimin Geng, Jasdev Singh, Jeffrey N. Myers, Yisheng Li, Mark S. Chambers
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 7, Iss 1, Pp 24-40 (2024)
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment; however, their oral toxicity profile is not well elucidated. This review aimed to investigate the prevalence of oral toxicities including xerostomia, mucositis/stomatitis, dysg
Externí odkaz:
https://doaj.org/article/3bbcadf3ffa54ca3a52f5788272ffd2c
Autor:
Mei Zhao, Tianxiao Wang, Frederico O. Gleber-Netto, Zhen Chen, Daniel J. McGrail, Javier A. Gomez, Wutong Ju, Mayur A. Gadhikar, Wencai Ma, Li Shen, Qi Wang, Ximing Tang, Sen Pathak, Maria Gabriela Raso, Jared K. Burks, Shiaw-Yih Lin, Jing Wang, Asha S. Multani, Curtis R. Pickering, Junjie Chen, Jeffrey N. Myers, Ge Zhou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Inactivating TP53 mutations leads to a loss of function of p53, but can also often result in oncogenic gain-of-function (GOF) of mutant p53 (mutp53) proteins which promotes tumor development and progression. The GOF activities of TP53 mutati
Externí odkaz:
https://doaj.org/article/439599fe4b0841cea0b2d92022192f6d
Autor:
Yinan He, Ben Bond-Lamberty, Allison N. Myers-Pigg, Michelle E. Newcomer, Joshua Ladau, James R. Holmquist, James B. Brown, Nicola Falco
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30470- (2024)
Coastal terrestrial-aquatic interfaces (TAIs) are crucial contributors to global biogeochemical cycles and carbon exchange. The soil carbon dioxide (CO2) efflux in these transition zones is however poorly understood due to the high spatiotemporal dyn
Externí odkaz:
https://doaj.org/article/d389e63dad6b45bab12836f29ea79c34
Publikováno v:
Journal of Orthopaedic Surgery, Vol 14 (2006)
Purpose. To assess early postoperative rehabilitation outcome following computer-assisted total knee arthroplasty (TKA) or standard instrumentation TKA using a medial parapatellar or subvastus approach. Methods. A prospective controlled trial of 70 c
Externí odkaz:
https://doaj.org/article/3d500c585e07446ab149101359387808
Autor:
Allison N. Myers-Pigg, Stephanie C. Pennington, Khadijah K. Homolka, Allison M. Lewis, Opal Otenburg, Kaizad F. Patel, Peter Regier, Madison Bowe, Maxim I. Boyanov, Nathan A. Conroy, Donnie J. Day, Cooper G. Norris, Edward J. O’Loughlin, Jesse Alan Roebuck, Lucie Stetten, Vanessa L. Bailey, Kenneth M. Kemner, Nicholas D. Ward, EXCHANGE Consortium
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-9 (2023)
Abstract Transferable and mechanistic understanding of cross-scale interactions is necessary to predict how coastal systems respond to global change. Cohesive datasets across geographically distributed sites can be used to examine how transferable a
Externí odkaz:
https://doaj.org/article/5d286691b1f242a0b7fa60ee2049a72e
Autor:
E. B. Graham, H.-S. Song, S. Grieger, V. A. Garayburu-Caruso, J. C. Stegen, K. D. Bladon, A. N. Myers-Pigg
Publikováno v:
Biogeosciences, Vol 20, Pp 3449-3457 (2023)
Pyrogenic organic matter (PyOM) from wildfires impacts river corridors globally and is widely regarded as resistant to biological degradation. Though recent work suggests PyOM may be more bioavailable than historically perceived, estimating bioavaila
Externí odkaz:
https://doaj.org/article/11223ad1a8534ae8bf06778ae9934489
Autor:
Hannah Gagg, Greg Wells, Sarah J. Danson, Spencer J. Collis, Juha Rantala, Ola Rominiyi, Callum Jones, Thomas Helleday, Katie N. Myers, Connor McGarrity-Cottrell, Sophie T. Williams, Samantha Conroy
Publikováno v:
F1000Research, Vol 12 (2024)
With diminishing returns and high clinical failure rates from traditional preclinical and animal-based drug discovery strategies, more emphasis is being placed on alternative drug discovery platforms. Ex vivo approaches represent a departure from bot
Externí odkaz:
https://doaj.org/article/0d07e3d1808746329649b8bab6580273