Zobrazeno 1 - 10
of 20
pro vyhledávání: '"N Miranda Nebane"'
Autor:
Gelare Ghajar-Rahimi, Amie M. Traylor, Bini Mathew, James R. Bostwick, N Miranda Nebane, Anna A. Zmijewska, Stephanie K. Esman, Saakshi Thukral, Ling Zhai, Vijaya Sambandam, Rita M. Cowell, Mark J. Suto, James F. George, Corinne E. Augelli-Szafran, Anupam Agarwal
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1888 (2022)
Acute kidney injury (AKI) is a major public health concern with significant morbidity and mortality and no current treatments beyond supportive care and dialysis. Preclinical studies have suggested that heme-oxygenase-1 (HO-1), an enzyme that catalyz
Externí odkaz:
https://doaj.org/article/25f0f94d8f124a2fac06bb9aa63b0b1c
Autor:
Brandon J. Metge, Heba Allah M. Alsheikh, Sarah C. Kammerud, Dongquan Chen, Devika Das, N. Miranda Nebane, J. Robert Bostwick, Lalita A. Shevde, Rajeev S. Samant
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-14 (2024)
Abstract Metastatic dissemination from the primary tumor is a complex process that requires crosstalk between tumor cells and the surrounding milieu and involves the interplay between numerous cellular-signaling programs. Epithelial–mesenchymal tra
Externí odkaz:
https://doaj.org/article/fdb5e2dddfe24017af39bdd3f65354a8
Autor:
Carlos C Goller, Mehreen Arshad, James W Noah, Subramaniam Ananthan, Carrie W Evans, N Miranda Nebane, Lynn Rasmussen, Melinda Sosa, Nichole A Tower, E Lucile White, Benjamin Neuenswander, Patrick Porubsky, Brooks E Maki, Steven A Rogers, Frank Schoenen, Patrick C Seed
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e96054 (2014)
Uropathogenic Escherichia coli (UPEC) is the leading cause of community-acquired urinary tract infections (UTIs), with over 100 million UTIs occurring annually throughout the world. Increasing antimicrobial resistance among UPEC limits ambulatory car
Externí odkaz:
https://doaj.org/article/87e084b83fca45db96122f19cf43b049
Autor:
Lynn Rasmussen, Shalisa Sanders, Melinda Sosa, Sara McKellip, N. Miranda Nebane, Yohanka Martinez-Gzegozewska, Andrew Reece, Pedro Ruiz, Anna Manuvakhova, Ling Zhai, Brooke Warren, Aliyah Curry, Qinghua Zeng, J. Robert Bostwick, Paige N. Vinson
Publikováno v:
SLAS Discovery, Vol 29, Iss 5, Pp 100160- (2024)
Four years after the beginning of the COVID-19 pandemic, it is important to reflect on the events that have occurred during that time and the knowledge that has been gained. The response to the pandemic was rapid and highly resourced; it was also bui
Externí odkaz:
https://doaj.org/article/6dbac02830044c3ab9f63c4c7d35bd4c
Publikováno v:
Microbiology spectrum. 10(5)
Pseudomonas aeruginosa is an opportunistic pathogen that has been declared by the World Health Organization as a "priority 1 critical pathogen" needing immediate new strategies for chemotherapy. During infection, P. aeruginosa uses redundant mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09eff9cc31db50dce98effa0de0e6d54
https://pubmed.ncbi.nlm.nih.gov/36098531
https://pubmed.ncbi.nlm.nih.gov/36098531
Autor:
Carolyn A, Robinson, Terri D, Lyddon, Hwi Min, Gil, David T, Evans, Yury V, Kuzmichev, Jonathan, Richard, Andrés, Finzi, Sarah, Welbourn, Lynn, Rasmussen, N Miranda, Nebane, Vandana V, Gupta, Sam, Ananthan, Zhaohui, Cai, Elizabeth R, Wonderlich, Corinne E, Augelli-Szafran, Robert, Bostwick, Roger G, Ptak, Susan M, Schader, Marc C, Johnson
Publikováno v:
Viruses. 14(4)
HIV-1 Vpu targets the host cell proteins CD4 and BST-2/Tetherin for degradation, ultimately resulting in enhanced virus spread and host immune evasion. The discovery and characterization of small molecules that antagonize Vpu would further elucidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1b70aad733480ddb32f93e78769269e
https://pubmed.ncbi.nlm.nih.gov/35458546
https://pubmed.ncbi.nlm.nih.gov/35458546
Autor:
N. Miranda Nebane, Yury V Kuzmichev, Elizabeth R. Wonderlich, Marc C. Johnson, Jonathan Richard, Susan M. Schader, Sarah Welbourn, Andrés Finzi, Corinne E. Augelli-Szafran, Vandana V. Gupta, Roger G. Ptak, Terri D. Lyddon, Carolyn A. Robinson, Robert Bostwick, Hwi Min Gil, Zhaohui Cai, Sam Ananthan, Lynn Rasmussen, David T. Evans
HIV-1 Vpu targets the host cell proteins CD4 and BST-2/Tetherin for degradation, ultimately resulting in enhanced virus spread and host immune evasion. The discovery and characterization of small molecules that antagonize Vpu would further elucidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09ea728eb1d665c2ecfc789c351c71ad
https://doi.org/10.1101/2021.07.30.454560
https://doi.org/10.1101/2021.07.30.454560
Autor:
Marie K. Mankowski, N. Miranda Nebane, Andrew Jay Brazier, Sara J. Buhrlage, Vikas Misra, Dana Gabuzda, Erez Pery, Roger G. Ptak, Lynn Rasmussen, Kottampatty S. Rajendran, Ann M. Sheehy, E. Lucile White
Publikováno v:
Journal of Biological Chemistry. 290:10504-10517
APOBEC3G (A3G) is a cellular cytidine deaminase that restricts HIV-1 replication by inducing G-to-A hypermutation in viral DNA and by deamination-independent mechanisms. HIV-1 Vif binds to A3G, resulting in its degradation via the 26 S proteasome. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db3565ad06467fd86deade1aa0992fb
https://doi.org/10.1074/jbc.m114.626903
https://doi.org/10.1074/jbc.m114.626903
Autor:
Mary-Ann Bjornsti, N. Miranda Nebane, Russell Sheppard, Sara McKellip, Melinda Sosa, Kanupriya Whig, Tatjana Coric, Lynn Rasmussen, LaKeisha Woods, E. Lucile White
Publikováno v:
SLAS Technology. 18:334-339
The process of validating an assay for high-throughput screening (HTS) involves identifying sources of variability and developing procedures that minimize the variability at each step in the protocol. The goal is to produce a robust and reproducible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea5b9f201bab46a487ad52d953433f5
https://doi.org/10.1177/2211068213486786
https://doi.org/10.1177/2211068213486786
Autor:
Joseph A. Maddry, Lisha Zhang, Sara McKellip, Melinda Sosa, N. Miranda Nebane, Yujie Li, Valerie Neubauer, Judith V. Hobrath, Nice Shindo, Lynn Rasmussen, Krister Wennerberg, Subramaniam Ananthan, E. Lucile White, Edina Harsay, Gary A. Piazza
Publikováno v:
ChemBioChem. 11:1291-1301
Most of the components of the membrane and protein traffic machinery were discovered by perturbing their functions, either with bioactive compounds or by mutations. However, the mechanisms responsible for exocytic transport vesicle formation at the G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1104f0e3ad11168a4353355d435732
https://doi.org/10.1002/cbic.200900681
https://doi.org/10.1002/cbic.200900681