Zobrazeno 1 - 10
of 123
pro vyhledávání: '"N McCracken"'
Autor:
Jonathan M. Tsai, Maia Shoham, Nathaniel B. Fernhoff, Benson M. George, Kristopher D. Marjon, Melissa N. McCracken, Kevin S. Kao, Rahul Sinha, Anne Kathrin Volkmer, Masanori Miyanishi, Jun Seita, Yuval Rinkevich, Irving L. Weissman
Publikováno v:
Blood Advances, Vol 3, Iss 18, Pp 2713-2721 (2019)
Peritoneal adhesions are pathological fibroses that ensnare organs after abdominal surgery. This dense connective tissue can cause small bowel obstruction, female infertility, and chronic abdominal pain. The pathogenesis of adhesions is a fibrotic re
Externí odkaz:
https://doaj.org/article/b43ada39bb3b4e929bf7e82a1f6406aa
Autor:
Brendan T Finicle, Kazumi H Eckenstein, Alexey S Revenko, Brooke A Anderson, W Brad Wan, Alison N McCracken, Daniel Gil, David A Fruman, Stephen Hanessian, Punit P Seth, Aimee L Edinger
Publikováno v:
Nucleic Acids Research. 51:1583-1599
Inefficient endosomal escape remains the primary barrier to the broad application of oligonucleotide therapeutics. Liver uptake after systemic administration is sufficiently robust that a therapeutic effect can be achieved but targeting extrahepatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fde1b5fd23940ce7c0ce0235ad04603
https://doi.org/10.1093/nar/gkad023
https://doi.org/10.1093/nar/gkad023
Autor:
Donald B. Kohn, Owen N. Witte, Antoni Ribas, Thinle Chodon, Richard C. Koya, Navdeep Saini, Xiaoyan Wang, Roger P. Hollis, Michelle Ho, Michael L. Kaufman, Melissa N. McCracken, Eric H. Gschweng
Supplementary Video 1. This is a 3D reconstruction of a 250uCi 18F-FHBG PET/CT scan of an ESO/TK mouse 3h after conscious uptake. Notable areas of uptake are the long bones of the arms and legs, sternum, spine, and thymus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b0ef9b8c3d443f0f9c3964bc6ec7da
https://doi.org/10.1158/0008-5472.22404393.v1
https://doi.org/10.1158/0008-5472.22404393.v1
Autor:
Anna M. Wu, Antoni Ribas, Owen N. Witte, Felix B. Salazar, Kirstin A. Zettlitz, Melissa N. McCracken, Stephen Mok, Helena Escuin-Ordinas, Richard Tavaré
Supplemental Tables S1-S4: Ex vivo biodistribution of 89Zr-malDFO-169 cDb in wt and CD8-blocked ARK mice (S1); Ex vivo biodistribution of 89Zr-malDFO-169 cDb in the adoptive T cell transfer model (S2); Ex vivo biodistribution of 89Zr-malDFO-169 cDb i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e96528209b6c496772823b0ace64aca
https://doi.org/10.1158/0008-5472.22408050.v1
https://doi.org/10.1158/0008-5472.22408050.v1
Autor:
Donald B. Kohn, Owen N. Witte, Antoni Ribas, Thinle Chodon, Richard C. Koya, Navdeep Saini, Xiaoyan Wang, Roger P. Hollis, Michelle Ho, Michael L. Kaufman, Melissa N. McCracken, Eric H. Gschweng
Engineering immunity against cancer by the adoptive transfer of hematopoietic stem cells (HSC) modified to express antigen-specific T-cell receptors (TCR) or chimeric antigen receptors generates a continual supply of effector T cells, potentially pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328387b41310d56093cc717296325ce9
https://doi.org/10.1158/0008-5472.c.6506595.v1
https://doi.org/10.1158/0008-5472.c.6506595.v1
Data from An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy
Autor:
Anna M. Wu, Antoni Ribas, Owen N. Witte, Felix B. Salazar, Kirstin A. Zettlitz, Melissa N. McCracken, Stephen Mok, Helena Escuin-Ordinas, Richard Tavaré
The rapidly advancing field of cancer immunotherapy is currently limited by the scarcity of noninvasive and quantitative technologies capable of monitoring the presence and abundance of CD8+ T cells and other immune cell subsets. In this study, we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0741cc57fb79b05ca3a7bc276523c0e2
https://doi.org/10.1158/0008-5472.c.6507450.v1
https://doi.org/10.1158/0008-5472.c.6507450.v1
Autor:
Anna M. Wu, Antoni Ribas, Owen N. Witte, Felix B. Salazar, Kirstin A. Zettlitz, Melissa N. McCracken, Stephen Mok, Helena Escuin-Ordinas, Richard Tavaré
Supplemental Methods and References: Description of additional methods and procedures used in the study. Also includes Supplemental References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001c1aac05ba71742157611174fad6e9
https://doi.org/10.1158/0008-5472.22408053
https://doi.org/10.1158/0008-5472.22408053
Autor:
R. Veluswamy, S. Bhalla, R. Mehra, O. Gligich, M.C. Garassino, C. Oliva, C. Gorcea-Carson, N. McCracken
Publikováno v:
Journal of Thoracic Oncology. 18:S85
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1373fc6eb8625cb5ead7b6fe7b0feab9
https://doi.org/10.1016/s1556-0864(23)00332-5
https://doi.org/10.1016/s1556-0864(23)00332-5
Autor:
Michael Zhang, Gregor Hutter, Suzana A Kahn, Tej D Azad, Sharareh Gholamin, Chelsea Y Xu, Jie Liu, Achal S Achrol, Chase Richard, Pia Sommerkamp, Matthew Kenneth Schoen, Melissa N McCracken, Ravi Majeti, Irving Weissman, Siddhartha S Mitra, Samuel H Cheshier
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153550 (2016)
Tumor-associated macrophages (TAMs) represent an important cellular subset within the glioblastoma (WHO grade IV) microenvironment and are a potential therapeutic target. TAMs display a continuum of different polarization states between antitumorigen
Externí odkaz:
https://doaj.org/article/c25227bd858d4ee192c10a749e29674d
Autor:
Brendan T. Finicle, Cuauhtemoc Ramirez, Stephen Hanessian, Vito Vece, Sylvestre P J T Bachollet, Nadine Ben Romdhane, Elizabeth Selwan, Amogha Dahal, Alison N. McCracken, Aimee L. Edinger
Publikováno v:
ACS Med Chem Lett
[Image: see text] A synthetic sphingolipid related to a ring-constrained hydroxymethyl pyrrolidine analog of FTY720 that was known to starve cancer cells to death was chemically modified to include a series of alkoxy-tethered 3,6-substituted 1,2-pyri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b883ae1745f3fd992109a7830cb9ab9
https://doi.org/10.1021/acsmedchemlett.9b00553
https://doi.org/10.1021/acsmedchemlett.9b00553