Zobrazeno 1 - 10
of 148
pro vyhledávání: '"N Mandir"'
Autor:
Nicholas A. Wright, N Mandir, Robert A. Goodlad, Harpreet Wasan, Peter Sasieni, Ken C. Liu, Walter F. Bodmer, Hyun-Sook Park, Angela Winnett
The functional effects of APC (adenomatous polyposis coli gene) germ-line mutations on crypt fission and cell proliferation were investigated in the normal intestine of human familial adenomatous polyposis (FAP) and multiple intestinal neoplasia (MIN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a87bc98f17c927d1777c24e69a71a1
https://doi.org/10.1002/(sici)1096-9896(199807)185:3<246::aid-path90>3.0.co
https://doi.org/10.1002/(sici)1096-9896(199807)185:3<246::aid-path90>3.0.co
Publikováno v:
British Journal of Nutrition. 100:711-721
Fermentation of carbohydrates in the colon can stimulate cell proliferation and could thus be a cancer risk. The effects of resistant carbohydrates, i.e. those not digested and absorbed in the small intestine, on cell proliferation, crypt fission and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0238db6c642b8378df693a0b934fd724
https://doi.org/10.1017/s0007114508901276
https://doi.org/10.1017/s0007114508901276
Autor:
N Mandir, S. K. Lam, Sérgio Britto Garcia, Nicholas A. Wright, Robert A. Goodlad, WM Wong, Bcy Wong
Publikováno v:
Gut. 50:212-217
Background: The histogenesis of human colorectal hyperplastic polyps and colorectal adenomas is poorly understood even now. Method: Human colorectal adenomas, hyperplastic polyps, and normal colorectal mucosae (patients with familial adenomatous poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199ece47435c40c1962cd908a756e99c
https://doi.org/10.1136/gut.50.2.212
https://doi.org/10.1136/gut.50.2.212
Publikováno v:
Alimentary Pharmacology & Therapeutics. 15:1681-1686
Background: Many experiments have indicated that the gut glucagons (enteroglucagons) are associated with cell proliferation in the small intestine. However, recent studies have failed to show trophic effects of glicentin (enteroglucagon) on the intes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5f7fd5bbdf0fc444a49e2455c3694c4
https://doi.org/10.1046/j.1365-2036.2001.01082.x
https://doi.org/10.1046/j.1365-2036.2001.01082.x
Publikováno v:
Regulatory Peptides. 87:83-90
Background: Keratinocyte growth factor (KGF) is a potent mitogen and may be of value for the treatment of conditions such as short bowel syndrome and chemotherapy-induced mucositis. However the most efficacious route and method of administration is u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94b4de788c2cee3ba7e31ec9be90808
https://doi.org/10.1016/s0167-0115(99)00113-5
https://doi.org/10.1016/s0167-0115(99)00113-5
Publikováno v:
Gut. 42:799-806
Background—Fermentable dietary fibre has many effects on the gastrointestinal tract. One is to alter epithelial crypt cell proliferation, especially in the colon. A discrepancy between epithelial cell production rates and intestinal weights has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5acdb89ecda1990c571f24c79df59e3
https://doi.org/10.1136/gut.42.6.799
https://doi.org/10.1136/gut.42.6.799
Autor:
M. A. Ghatei, A Higham, Raymond J. Playford, Karim Meeran, N Mandir, Robert A. Goodlad, Stephen R. Bloom, Tania Marchbank
Publikováno v:
The Journal of Pathology. 184:316-322
Keratinocyte growth factor (KGF) is a mitogen found throughout the gastrointestinal tract, but its role in gastrointestinal pathophysiology is unclear. The effect of recombinant KGF on gut growth and repair has been examined using a variety of in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dcce1e81d5c0c951cb73149a807e835
https://doi.org/10.1002/(sici)1096-9896(199803)184:3<316::aid-path3>3.0.co
https://doi.org/10.1002/(sici)1096-9896(199803)184:3<316::aid-path3>3.0.co
Autor:
Kimberley Howarth, Annabelle Lewis, Lisa Willis, Andrew Silver, Bradley Spencer–Dene, Richard Poulsom, Philip East, Matthew E. Cockman, Robert A. Goodlad, Gordon Stamp, Nicholas A. Wright, N Mandir, Andrew Rowan, Emma Nye, Maesha Deheragoda, Patrick J. Pollard, Ian Tomlinson, Stefania Segditsas, Amy McCart
Publikováno v:
Gastroenterology. 136(7)
BACKGROUND and AIMS: We previously demonstrated that the 2 APC mutations in human colorectal tumors are coselected, because tumorigenesis requires an optimal level of Wnt signaling. We and others subsequently showed that the truncated APC proteins in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060a007fe0583a30bce0d5f0c4ed268c
https://pubmed.ncbi.nlm.nih.gov/19248780
https://pubmed.ncbi.nlm.nih.gov/19248780
Autor:
N. Mandir, Robert A. Goodlad
Publikováno v:
Cell proliferation. 41(2)
Objective: Dietary conjugated linoleic acids (CLA) have had many health benefits claimed for them, including antineoplastic actions. Materials and methods: The effects of the predominant forms of CLA, namely the c9t11 and t10c12 isomers, or a mixture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72964f50c653af79ab8ce7ff8265597
https://pubmed.ncbi.nlm.nih.gov/18336472
https://pubmed.ncbi.nlm.nih.gov/18336472
Publikováno v:
Cell proliferation. 39(5)
Many mouse models of neoplasia and pre‐neoplasia require the examination of whole mounts of the gastrointestinal tract. A simple device has been produced to facilitate the rapid preparation of mouse intestines for subsequent quantification of tumou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2cfc66b015b37667bbbb0e35b49442
https://pubmed.ncbi.nlm.nih.gov/16987142
https://pubmed.ncbi.nlm.nih.gov/16987142