Zobrazeno 1 - 10
of 31
pro vyhledávání: '"N M Schechter"'
Autor:
N M Schechter, Yongsheng Ma, H S Lu, B. J. Longley, Lynda Tyrrell, D A Williams, Keith Langley, Ruth Halaban
Publikováno v:
Proceedings of the National Academy of Sciences. 94:9017-9021
Stem cell factor (SCF) is produced by stromal cells as a membrane-bound molecule, which may be proteolytically cleaved at a site close to the membrane to produce a soluble bioactive form. The proteases producing this cleavage are unknown. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47292d58f8a28ab0bcc8790559f8739a
https://doi.org/10.1073/pnas.94.17.9017
https://doi.org/10.1073/pnas.94.17.9017
Publikováno v:
The Journal of Immunology. 152:4062-4069
This study establishes the primary structure of human skin chymase and provides further evidence for the presence of a cathepsin G-like proteinase within human mast cells. The amino acid sequence of human skin chymase was established by protein metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09cba5e5dcab21ee1405484723f1a4eb
https://doi.org/10.4049/jimmunol.152.8.4062
https://doi.org/10.4049/jimmunol.152.8.4062
Publikováno v:
The Journal of Immunology. 145:2652-2661
Human mast cells can be divided into two subsets based on serine proteinase composition: a subset that contains the serine proteinases tryptase and chymase (MCTC), and a subset that contains only tryptase (MCT). In this study we examined both types o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d9d5e329fd2055638629907b24a64a9
https://doi.org/10.4049/jimmunol.145.8.2652
https://doi.org/10.4049/jimmunol.145.8.2652
Publikováno v:
Journal of cellular physiology. 176(2)
Protease activated receptors (PARs) compose a family of G protein signal transduction receptors activated by proteolysis. In this study, the susceptibility of PARs expressed on human keratinocytes and dermal fibroblasts to the human mast cell proteas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::10e3870ea00f7c47344b181e49697d4f
https://pubmed.ncbi.nlm.nih.gov/9648924
https://pubmed.ncbi.nlm.nih.gov/9648924
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 72(1)
By ultrastructure, human skin mast cell granules exhibit amorphous regions situated next to crystalline regions with scroll, lamellar, and grating/lattice-like configurations. The composition and function of these structural domains is unknown. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e55314cca1d30352368ae17fb2c11c6
https://pubmed.ncbi.nlm.nih.gov/7837788
https://pubmed.ncbi.nlm.nih.gov/7837788
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(8)
This study establishes the primary structure of human skin chymase and provides further evidence for the presence of a cathepsin G-like proteinase within human mast cells. The amino acid sequence of human skin chymase was established by protein metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32a6b8078f37a03082c2b8732894c089
https://pubmed.ncbi.nlm.nih.gov/8144971
https://pubmed.ncbi.nlm.nih.gov/8144971
Publikováno v:
The Journal of biological chemistry. 268(31)
The interactions of bovine pancreatic chymotrypsin (Chtr) and recombinant alpha 1-antichymotrypsin (rACT) and rACT variants were studied by kinetic and gel electrophoretic analyses, leading to the formulation of a general kinetic scheme that accounts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94a74d4dc37c3f080bb6bd3e12bbf9fa
https://pubmed.ncbi.nlm.nih.gov/7693693
https://pubmed.ncbi.nlm.nih.gov/7693693
Publikováno v:
The Journal of biological chemistry. 268(31)
Inhibition of human chymase by alpha 1-antichymotrypsin produces 3.5 mol of degraded inhibitor for every mol of chymase inhibited, resulting in a stoichiometry of inhibition (SI) of 4.5. In the present study, the substrate versus inhibitor properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b13e23751f1f843fc057fd06e789f49c
https://pubmed.ncbi.nlm.nih.gov/8226889
https://pubmed.ncbi.nlm.nih.gov/8226889
Publikováno v:
The American journal of pathology. 138(2)
The delayed-type hypersensitivity reaction (DHR) in human skin is prototypic for many inflammatory dermatoses. However the cellular events that precede gross lesion formation are unknown. In this study, inflammatory cell populations and adhesion mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7a300ed600c8d8d6d158791fb03e1da
https://pubmed.ncbi.nlm.nih.gov/1704193
https://pubmed.ncbi.nlm.nih.gov/1704193
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(8)
Human mast cells can be divided into two subsets based on serine proteinase composition: a subset that contains the serine proteinases tryptase and chymase (MCTC), and a subset that contains only tryptase (MCT). In this study we examined both types o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::998c2b0930fc0e003cdfca262cc03c6c
https://pubmed.ncbi.nlm.nih.gov/2212656
https://pubmed.ncbi.nlm.nih.gov/2212656