Zobrazeno 1 - 10
of 25
pro vyhledávání: '"N M McKechnie"'
Publikováno v:
The Journal of Experimental Medicine
Structural similarities between host self-antigens and infectious organisms may be involved in the expression of autoimmune reactivity and development of autoimmune disease. The unique eye pathology associated with Onchocerca volvulus infection, part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7eed8f002b2e2637519e09e75323216
https://doi.org/10.1084/jem.182.4.1121
https://doi.org/10.1084/jem.182.4.1121
Publikováno v:
British Journal of Ophthalmology. 75:54-60
Light microscopy (including fluorescence microscopy) and electron microscopy were applied to a study of the photoreceptor-retinal pigment epithelium (RPE) complex in a human eye which had been severely traumatised nine months prior to enucleation. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7ceaebca0caedcaebf95d2f9b0e721
https://doi.org/10.1136/bjo.75.1.54
https://doi.org/10.1136/bjo.75.1.54
Publikováno v:
Journal of Small Animal Practice. 31:64-68
Unilateral corneal epithelial inclusion cysts are recorded in a series of 16 dogs. The cysts were not congenital, there was no breed incidence, and in 11 patients there was history of corneal trauma or ulceration before cyst formation. There was some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e82cccefbc235adbd29f5c692e0f9cbe
https://doi.org/10.1111/j.1748-5827.1990.tb00722.x
https://doi.org/10.1111/j.1748-5827.1990.tb00722.x
Publikováno v:
The Journal of infectious diseases. 176(5)
Antigen Ov39, derived from Onchocerca volvulus, cross-reacts on both the T and B cell level with a nonhomologous human retinal antigen, hr44. Lewis rats were immunized to investigate the potential of these antigens to induce eye disease. Histologic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e1700ce613858cc0f0b46b1964aa71
https://pubmed.ncbi.nlm.nih.gov/9359736
https://pubmed.ncbi.nlm.nih.gov/9359736
Publikováno v:
Scopus-Elsevier
The ocular disease associated with infection with Onchocerca volvulus is unique in that there is a wealth of epidemiological evidence to support the casual nature of the association but there is little known about the pathogenic mechanisms involved.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2226f7562030dc49a5535b8b6981a591
https://pubmed.ncbi.nlm.nih.gov/8122928
https://pubmed.ncbi.nlm.nih.gov/8122928
Publikováno v:
Investigative ophthalmologyvisual science. 34(10)
Onchocerca volvulus, a filarial worm, is a major cause of infectious blindness and inflammatory eye disease. An autoimmune cause for ocular onchocerciasis has been suggested since the identification of a recombinant antigen of O. volvulus that shows
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc782b2bdf5142d913f4beb120e890dd
https://pubmed.ncbi.nlm.nih.gov/8360022
https://pubmed.ncbi.nlm.nih.gov/8360022
Autor:
G. Braun, F. Engelbrecht, Clare Gilbert, Vivienne Connor, James A. G. Whitworth, N M McKechnie, D. W. Taylor
Publikováno v:
The Journal of Experimental Medicine
Onchocerciasis (river blindness) is a major blinding disease in Africa, Central America, and South America. Loss of vision can be due to corneal change, optic atrophy, or chorioretinal disease. It has been suggested that autoimmunological reactions r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3b50e3d82ef1d15ba45e6affc94302
Autor:
N M, McKechnie, N F, Johnson
Publikováno v:
Albrecht von Graefes Archiv f�r Klinische und Experimentelle Ophthalmologie. 203:283-292
The retinae of anaesthetised Dutch rabbits were exposed to light of various known intensities for a period of 1 h. After this period the animals were sacrificed and tissue taken for investigation by light and electron microscopy. Changes were apparen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed74e828c6aad48a05ead9b6103f4d88
https://doi.org/10.1007/bf00409834
https://doi.org/10.1007/bf00409834
Autor:
N. M. McKechnie, W. S. Foulds
Publikováno v:
Albrecht von Graefes Archiv f�r Klinische und Experimentelle Ophthalmologie. 212:271-283
The retinae of anaesthetised Dutch rabbits were exposed to one of two intensities of white light for a period of 1 h. After exposure the animals were allowed to recover for various periods up to 4 weeks. The animals were then killed, and retinal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c03ebaa1499ea2e032d37d1ed9a36ee
https://doi.org/10.1007/bf00410521
https://doi.org/10.1007/bf00410521
Autor:
N M, McKechnie, W S, Foulds
Publikováno v:
Albrecht von Graefes Archiv f�r klinische und experimentelle Ophthalmologie. 215:305-325
The retinae of anaesthetised Dutch rabbits were exposed to light of various known intensities for one hour. Immediately after exposure the animals were killed and retinal and choroidal tissues were taken for investigation by electron microscopy from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574b6a695dafc7b6061390d5f4ab3601
https://doi.org/10.1007/bf00407669
https://doi.org/10.1007/bf00407669