Zobrazeno 1 - 10
of 14
pro vyhledávání: '"N M, Woods"'
Publikováno v:
Cellular Signalling. 11:805-811
We report the results using bioluminescent and fluorescent indicators to investigate maitotoxin-induced free Ca changes in single rat hepatocytes. Maitotoxin generated a steadily rising free Ca increase after a long lag period. The free Ca increase w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38125e7a5bf0142f52a87ac70098a74e
https://doi.org/10.1016/s0898-6568(99)00046-7
https://doi.org/10.1016/s0898-6568(99)00046-7
Publikováno v:
Cell Calcium. 11:353-360
Single rat hepatocytes, microinjected with the calcium-sensitive photoprotein aequorin, when stimulated with either phenylephrine or arg8-vasopressin exhibit agonist-specific oscillations in cytosolic free calcium levels (free Ca). In the majority of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d6a0c7452fb9cd38c8ba4c69ec9996
https://doi.org/10.1016/0143-4160(90)90038-v
https://doi.org/10.1016/0143-4160(90)90038-v
Publikováno v:
British journal of pharmacology. 129(4)
Previous studies have indicated the expression of multiple P2Y receptors by rat hepatocytes although they have not been identified. Here we show by reverse transcriptase-polymerase chain reaction (RT - PCR) that rat hepatocytes express mRNA encoding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::169979b6ba4b82ac92403d1538530e9e
https://pubmed.ncbi.nlm.nih.gov/10683201
https://pubmed.ncbi.nlm.nih.gov/10683201
Autor:
N M Woods, C Schöfl, J A C Lee, K S R Cuthbertson, Peter H. Cobbold, A Sanchez-Bueno, J D Birchall, C J Dixon
Aluminium is known to be toxic to cells from bone, brain and bone marrow but the molecular target(s) affected by Al3+ are not known. We show here that Al3+ disrupts the oscillatory free Ca2+ responses of hepatocytes exposed to the Ca2(+)-mobilizing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ff7560c486bfd0ac2b2fce815381a1
https://europepmc.org/articles/PMC1131614/
https://europepmc.org/articles/PMC1131614/
Publikováno v:
The Biochemical journal. 269(2)
Aequorin measurements of cytosolic free Ca2+ in single rat hepatocytes show that ADP and ATP, thought to act through the same P2Y purinoceptor, elicited very different responses in the majority of cells tested. ADP invariably induced transients of sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48dbb847aacf0cacc670a299a14c17c9
https://pubmed.ncbi.nlm.nih.gov/2386488
https://pubmed.ncbi.nlm.nih.gov/2386488
Many cells generate oscillations in cytoplasmic free Ca2+ concentration (‘free Ca’) when stimulated with Ca-mobilizing hormones. The frequency of repetitive free-Ca transients in a rat hepatocyte is a function of hormone concentration and can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517d2e7e59d7971d3addb7ab91ab4cf8
https://europepmc.org/articles/PMC1131485/
https://europepmc.org/articles/PMC1131485/
Single rat hepatocytes microinjected with the photoprotein aequorin were stimulated with glycogenolytic agonists or low concentrations of fluoroaluminate. Both protocols resulted in the generation of oscillations in cytosolic free Ca2+ levels from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012d712c4c8981e4b2525b45058ed1a2
https://europepmc.org/articles/PMC1136929/
https://europepmc.org/articles/PMC1136929/
Publikováno v:
Advances in second messenger and phosphoprotein research. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc36656914213dbf3f7770d045e6dabe
https://pubmed.ncbi.nlm.nih.gov/2169792
https://pubmed.ncbi.nlm.nih.gov/2169792
Publikováno v:
The Biochemical journal. 246(3)
The effect of the phorbol esters phorbol 12-myristate 13-acetate (TPA) and phorbol 12,13-dibutyrate (PDB) on changes in free Ca2+ concentration ([Ca2+]i) in single rat hepatocytes, microinjected with the photoprotein aequorin, were investigated. [Arg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438401e0a982407042271b5fb248d889
https://pubmed.ncbi.nlm.nih.gov/3479980
https://pubmed.ncbi.nlm.nih.gov/3479980
Publikováno v:
Nature. 319(6054)
In the stressed animal, the vasoactive hormones vasopressin and angiotensin-II and the neurotransmitter noradrenaline induce liver cells to release glucose from glycogen. The intracellular signal that links the cell-surface receptors for noradrenalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a36df87877602431a94ec34b817f38
https://pubmed.ncbi.nlm.nih.gov/3945348
https://pubmed.ncbi.nlm.nih.gov/3945348