Zobrazeno 1 - 10
of 47
pro vyhledávání: '"N M, Wilkie"'
Publikováno v:
Blood. 84:1790-1801
Macrophage inflammatory protein-1 alpha (MIP-1 alpha) and its human homologue GOS19.1/LD78 are members of the C-C chemokine/intercrine family of secreted proteins. They have proinflammatory properties and also inhibit cell cycle progression of hemato
Publikováno v:
Molecular and cellular biochemistry. 195(1-2)
Human macrophage inflammatory protein-1alpha (hMIP-1alpha) and human macrophage inflammatory protein-1beta (hMIP-1beta) are chemokines involved in a diverse range of immunological effects. Both hMIP-1alpha and hMIP-1beta are involved in the activatio
Publikováno v:
Oncology research. 6(3)
We report the independent isolation of a rearranged FGF-4 gene from a patient with chronic myeloid leukaemia. We show that the FGF-4 gene has been truncated 30 nucleotides 3' to the coding sequence and has been fused to the RNA processing signals fro
Publikováno v:
Oncogene. 6(11)
Expression of P0 RNA in some Burkitt lymphoma cell lines varies independently of levels of RNA derived from P1 and P2. These data suggest the possibility that expression of P0 RNA may be capable of independent regulation. In order to investigate this
Publikováno v:
The EMBO Journal. 3:389-395
An enhancer-type sequence has been identified in the promoter region for the herpes simplex virus type 1 (HSV-1) immediate early (IE) mRNA 3. The enhancer-type activity is host cell dependent, being greater in human cells and Syrian hamster cells (th
Autor:
N M Wilkie
Publikováno v:
Journal of Virology. 20:222-233
It has been proposed that the genome of herpes simplex virus type 1 (HSV-1) consists of two internal unique sequences, S and L, bounded by two sets of redundant sequences (P. Sheldrick and N. Berthelot, 1974). In this arrangement, terminal sequences
Autor:
Rita Cortini, N. M. Wilkie
Publikováno v:
Journal of General Virology. 39:259-280
Summary The ordering of restriction endonuclease fragments of HSV-2 DNA for physical maps has been studied using molecular hybridization techniques and the cleavage of isolated restriction endonuclease fragments with further restriction endonucleases
Publikováno v:
Journal of Virology. 31:265-276
Mutations (paar) in herpes simplex virus (HSV) which confer resistance to phosphonoacetic acid involve genes associated with virus-induced DNA polymerase activity. Two mutants of HSV (HSV-1 tsH and HSV-2 ts6) produce a thermolabile DNA polymerase act
Publikováno v:
Virology. 105:171-184
Resistance of herpes simplex viruses (HSV-1 and HSV-2) to acycloguanosine (ACG) is determined by the two genetic loci of HSV coding for deoxypyrimidine kinase (thymidine kinase) and DNA polymerase activity. Mutants of HSV-1 which induce defective deo
Publikováno v:
Journal of Virological Methods. 6:183-191
Transfection of HSV DNA into rat embryo cells (previously an inefficient procedure) is enhanced more than 30-fold by simultaneous treatment with 20% glucose and 10% DMSO 4 h after transfection. The action of these compounds was efficient only when us