Výsledky vyhledávání - "N M, Bleehen"

Measurements of resting energy expenditure and body composition before and after treatment of small cell lung cancer

Autor: N. M. Bleehen, Marinos Elia, R. J. Osborne, Susan A. Jebb, Adrian K. Dixon

Summary Background Many patients with small cell lung cancer are reported to lose weight, but the mechanism of this effect is unclear. Patients and methods Measurements of resting energy expenditure (REE), using indirect calorimetry and body composit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9806cf0ea388c3e06def61946690107c
https://ora.ox.ac.uk/objects/uuid:3870dbf3-5a88-427c-add5-b4f4eef71acc

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The role of post-operative radiotherapy in non-small-cell lung cancer: a multicentre randomised trial in patients with pathologically staged T1-2, N1-2, M0 disease

Autor: Richard Stephens, N. M. Bleehen, K Moghissi, H M Yosef, David Machin, David J. Girling

Publikováno v: British Journal of Cancer. 74:632-639

The role of post-operative radiotherapy for patients with non-small-cell lung cancer (NSCLC) is unclear despite five previous randomised trials. One deficiency with these trials was that they did not include adequate TNM staging, and so the present r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e42e44ac02facb692b7fa8ffdbff3425
https://doi.org/10.1038/bjc.1996.413

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Randomised trial of four-drug vs less intensive two-drug chemotherapy in the palliative treatment of patients with small-cell lung cancer (SCLC) and poor prognosis

Autor: Penelope Hopwood, N. M. Bleehen, G Lallemand, A.J. Bailey, Richard Stephens, David Machin, David J. Girling

Publikováno v: British Journal of Cancer. 73:406-413

This randomised trial was conducted to compare a four-drug chemotherapy regimen as a control vs a less intensive two-drug regimen in terms of quality of life (QL), tumour response and survival in the palliative treatment of patients with small-cell l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e2c67304dadfc4cdd07841d009aa02e5
https://doi.org/10.1038/bjc.1996.71

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Phase I study of etoposide with SDZ PSC 833 as a modulator of multidrug resistance in patients with cancer

Autor: I F Dennis, D.J. Boote, M H Brampton, C Laburte, R J Osborne, S Hensel, John F. Smyth, N M Bleehen, P R Twentyman

Publikováno v: Journal of Clinical Oncology. 14:610-618

PURPOSE To determine the maximum-tolerated dose (MTD) and toxicity of PSC 833 infusion administered with etoposide for 5 days in patients with cancer, and to determine the effect of PSC 833 on etoposide pharmacokinetics. PATIENTS AND METHODS Thirty-f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5c1aa03dd3b2308dc82ec102afb2c7
https://doi.org/10.1200/jco.1996.14.2.610

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Radiation myelopathy: Estimates of risk in 1048 patients in three randomized trials of palliative radiotherapy for non-small cell lung cancer

Autor: Nicholas S. Reed, D.J. Radstone, A Lamont, N. M. Bleehen, David J. Girling, David Machin, Richard Stephens, F.R. Macbeth, T E Wheldon

Publikováno v: Clinical Oncology. 8:176-181

Radiation myelopathy (RM) is an uncommon but serious late effect of thoracic radiotherapy (RT), which oncologists try to avoid by careful planning and dose selection. Five patients with RM are described from among 1048 with inoperable non-small cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2cc67d6688ff58eba5e3a4416782fde
https://doi.org/10.1016/s0936-6555(96)80042-2

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Randomized trial of palliative two-fraction versus more intensive 13-fraction radiotherapy for patients with inoperable non-small cell lung cancer and good performance status

Autor: F.R. Macbeth, David J. Girling, Richard Stephens, Penelope Hopwood, N. M. Bleehen, David Machin, J. J. Bolger, J. Cartmell, A.J. Bailey

Publikováno v: Clinical Oncology. 8:167-175

In patients with non-metastatic but inoperable non-small cell lung cancer that is locally too extensive for radical radiotherapy (RT), but who have good performance status, it is important to determine whether thoracic RT should be the minimum that i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::57b105018f64c4c99d69a2afe4901fe1
https://doi.org/10.1016/s0936-6555(96)80041-0

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Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients

Autor: R. Ward, Ian F. Dennis, VM Laurence, N. M. Bleehen

Publikováno v: British Journal of Cancer

Nicotinamide and carbogen breathing are both effective radiosensitisers in experimental tumour models and are even more effective in combination. This study was to investigate the feasibility of using the agents in combination in patients and to meas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c20b348f7c3b7e49866d81cf12f267
https://doi.org/10.1038/bjc.1995.303

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