Zobrazeno 1 - 10
of 77
pro vyhledávání: '"N M, Bazhan"'
Autor:
T. V. Jakovleva, A. Yu. Kazantseva, A. D. Dubinina, N. Yu. Balybina, K. O. Baranov, E. N. Makarova, N. M. Bazhan
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 26, Iss 2, Pp 159-168 (2022)
The f ibroblast growth factor 21 (FGF21) synthesized in the liver, acting as a hormone, increases insulin sensitivity and energy expenditure. FGF21 administration has potent benef icial effects on obesity and diabetes in humans, cynomolgus monkey, an
Externí odkaz:
https://doaj.org/article/ec813caca3d3467abe360b1e2f2ab3a3
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 24, Iss 8, Pp 844-852 (2020)
In rodents, the most adequate model of human diet-induced obesity is obesity caused by the consumption of a sweet-fat diet (SFD), which causes more pronounced adiposity in females than in males. The aim of this work was to determine the sex-associate
Externí odkaz:
https://doaj.org/article/5c2924bc4bcf4306b6dbce6dab5f6876
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 24, Iss 4, Pp 427-434 (2020)
A positive effect of estradiol on insulin sensitivity has been shown for females and males. Insulin sensitivity is higher in females than in males, and males show a greater tendency to develop metabolic disorders. It is believed that these sex differ
Externí odkaz:
https://doaj.org/article/136dc9689ed9456dba069a632625b9ef
Autor:
E. N. Makarova, T. V. Yakovleva, N. Yu. Balyibina, K. O. Baranov, E. I. Denisova, A. D. Dubinina, N. A. Feofanova, N. M. Bazhan
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 24, Iss 2, Pp 200-208 (2020)
Hypothalamic melanocortin 4 receptors (MC4R) regulate energy balance. Mutations in the MC4R gene are the most common cause of monogenic obesity in humans. Fibroblast growth factor 21 (FGF21) is a promising antiobesity agent, but its effects on melano
Externí odkaz:
https://doaj.org/article/d33360801fcb4c57bb83ae5344227c44
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 23, Iss 1, Pp 62-66 (2019)
Fasting has become increasingly popular for treatment and prevention of obesity. Sex differences in the mechanisms of adaptation to fasting may contribute to choosing a therapeutic strategy for correction of metabolic disorders. Hepatokine fibroblast
Externí odkaz:
https://doaj.org/article/527b9f46939c43efa416112655f9ab6b
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 22, Iss 2, Pp 265-272 (2018)
The lethal yellow mutation in agouti loci (Ay mutation) reduces the activity of melanocortin (MC) receptors and causes hyperphagia, obesity and type two diabetes mellitus in aging mice (Ay mice). It is unknown if changes in distinct elements of the m
Externí odkaz:
https://doaj.org/article/a7ad4bc08835496aa950d85fbceef7b2
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 21, Iss 7, Pp 833-840 (2017)
Reduced insulin sensitivity plays an important role in the pathogenesis of type II diabetes. There are sex differences in the development of metabolic disorders. The aim of this work was to investigate the insulin signal transduction gene expression
Externí odkaz:
https://doaj.org/article/c9390858b8e64c7d844e25972dc13c8a
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 20, Iss 2, Pp 138-144 (2016)
Hypothalamic melanortin receptor (MCR) activation inhibits appetite. Neuropeptide Y (NPY) and Agouti Related Protein (AgRP) are coexpressed in some hypothalamic neurons and stimulate feeding, NPY via inhibition of MCR-expressing neurons, and AgRP via
Externí odkaz:
https://doaj.org/article/c2b3bef521f1496289d8e81d14e12515
Publikováno v:
Vavilov Journal of Genetics and Breeding
Vavilovskij Žurnal Genetiki i Selekcii, Vol 24, Iss 4, Pp 427-434 (2020)
Vavilovskij Žurnal Genetiki i Selekcii, Vol 24, Iss 4, Pp 427-434 (2020)
A positive effect of estradiol on insulin sensitivity has been shown for females and males. Insulin sensitivity is higher in females than in males, and males show a greater tendency to develop metabolic disorders. It is believed that these sex differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37d52ccf2a9c28ca53e423d6f8fae31
https://doi.org/10.18699/vj20.635
https://doi.org/10.18699/vj20.635
Autor:
N Yu Balyibina, E I Denisova, T. V. Yakovleva, K O Baranov, Anastasia Dubinina, N. A. Feofanova, Elena N. Makarova, N. M. Bazhan
Publikováno v:
Vavilov Journal of Genetics and Breeding. 24:200-208
Hypothalamic melanocortin 4 receptors (MC4R) regulate energy balance. Mutations in the MC4R gene are the most common cause of monogenic obesity in humans. Fibroblast growth factor 21 (FGF21) is a promising antiobesity agent, but its effects on melano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a90ecaeabfc036308227590e49918393
https://doi.org/10.18699/vj20.40-o
https://doi.org/10.18699/vj20.40-o