Zobrazeno 1 - 10
of 27
pro vyhledávání: '"N Laila, Huq"'
Autor:
Abu Sayeed M. Mahmud, Christine A. Seers, N. Laila Huq, Lianyi Zhang, Catherine A. Butler, Caroline Moore, Keith J. Cross, Eric C. Reynolds
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The Arg-specific gingipains of Porphyromonas gingivalis RgpA and RgpB have 97% identical sequences in their catalytic domains yet their propeptides are only 76% identical. RgpA isolates as a proteinase–adhesin complex (HRgpA) which hinders
Externí odkaz:
https://doaj.org/article/62373cb149f64e4582bd5da8e3e92f8e
Publikováno v:
Journal of Oral Microbiology, Vol 13, Iss 1 (2021)
Background: The cell-surface cysteine proteinases RgpA, RgpB (Arg-gingipain), and Kgp (Lys-gingipain) are major virulence factors of P. gingivalis, a keystone pathogen in the development of destructive periodontal disease. The gingipains function as
Externí odkaz:
https://doaj.org/article/bca681ae1ef24739a5c036c87de9cb02
Autor:
Stuart G Dashper, Deanne V Catmull, Sze-Wei Liu, Helen Myroforidis, Ilya Zalizniak, Joseph E A Palamara, N Laila Huq, Eric C Reynolds
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162322 (2016)
Glass ionomer cements (GIC) are dental restorative materials that are suitable for modification to help prevent dental plaque (biofilm) formation. The aim of this study was to determine the effects of incorporating casein phosphopeptide-amorphous cal
Externí odkaz:
https://doaj.org/article/030d21ebd4d54f0dae4804ed831452d7
Publikováno v:
Journal of Oral Microbiology
article-version (VoR) Version of Record
Journal of Oral Microbiology, Vol 13, Iss 1 (2021)
article-version (VoR) Version of Record
Journal of Oral Microbiology, Vol 13, Iss 1 (2021)
Background: The cell-surface cysteine proteinases RgpA, RgpB (Arg-gingipain), and Kgp (Lys-gingipain) are major virulence factors of P. gingivalis, a keystone pathogen in the development of destructive periodontal disease. The gingipains function as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9ef7bda60204bfebfa3b918a2a65d4
http://europepmc.org/articles/PMC7733959
http://europepmc.org/articles/PMC7733959
Autor:
N Laila Huq, Christine A Seers, Elena C Y Toh, Stuart G Dashper, Nada Slakeski, Lianyi Zhang, Brent R Ward, Vincent Meuric, Dina Chen, Keith J Cross, Eric C Reynolds
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65447 (2013)
Porphyromonas gingivalis is a major pathogen associated with chronic periodontitis. The organism's cell-surface cysteine proteinases, the Arg-specific proteinases (RgpA, RgpB) and the Lys-specific proteinase (Kgp), which are known as gingipains have
Externí odkaz:
https://doaj.org/article/cdf04f60a77944a79b64715edf7fb00b
Autor:
N. Laila Huq, Keith J. Cross, Christine A. Seers, Yu-Yen Chen, Eric C. Reynolds, Paul D. Veith, Dhana G. Gorasia, Lianyi Zhang
Publikováno v:
Journal of proteome research. 17(8)
Porphyromonas gingivalis is a keystone periodontal pathogen that has been associated with autoimmune disorders. The cell surface proteases Lys-gingipain (Kgp) and Arg-gingipains (RgpA and RgpB) are major virulence factors, and their proteolytic activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ee746f5fb9414ed1f8defd68477c8a
https://pubmed.ncbi.nlm.nih.gov/29984580
https://pubmed.ncbi.nlm.nih.gov/29984580
Autor:
Glen Walker, Peiyan Shen, N. Laila Huq, Bill Madytianos, Coralie Reynolds, Eric C. Reynolds, Li-Ming Bhutta, Yi Yuan, Keith J. Cross, David P. Stanton, Boon Loh, Sarah Peterson
Publikováno v:
Biomineralization ISBN: 9789811310010
Casein phosphopeptides derived from tryptic digests of milk caseins spontaneously assemble with calcium and phosphate ions at high pH to form casein phosphopeptide-amorphous calcium phosphate complexes (CPP-ACP). These complexes have been shown to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::921cb551c0f4f55b214a492110c3fecd
https://doi.org/10.1007/978-981-13-1002-7_23
https://doi.org/10.1007/978-981-13-1002-7_23
Autor:
Belinda J. Michell, Christine A. Seers, Susanne C. Feil, Keith J. Cross, Michael W. Parker, Michael A. Gorman, Eric C. Reynolds, N. Laila Huq
Publikováno v:
Protein Science. 24:162-166
The oral pathogen Porphyromonas gingivalis is a keystone pathogen in the development of chronic periodontitis. Gingipains, the principle virulence factors of P. gingivalis are multidomain, cell-surface proteins containing a cysteine protease domain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a95d9938e31a37644af094f2611190f0
https://doi.org/10.1002/pro.2589
https://doi.org/10.1002/pro.2589
Autor:
Sze Wei Liu, N. Laila Huq, Ilya Zalizniak, Joseph E.A. Palamara, Helen Myroforidis, Stuart G. Dashper, Eric C. Reynolds, Deanne V. Catmull
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162322 (2016)
PLoS ONE
PLoS ONE
Glass ionomer cements (GIC) are dental restorative materials that are suitable for modification to help prevent dental plaque (biofilm) formation. The aim of this study was to determine the effects of incorporating casein phosphopeptide-amorphous cal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab09a391169cea575f368b171d6b144
http://europepmc.org/articles/PMC5010225?pdf=render
http://europepmc.org/articles/PMC5010225?pdf=render
Autor:
Stuart G. Dashper, Troy J. Attard, N. Laila Huq, Eric C. Reynolds, Keith J. Cross, David P. Stanton, Elena C. Y. Toh
Publikováno v:
International Dairy Journal. 24:22-26
The bovine-casein-derived peptide κ-casein (109–137) has been shown to inhibit the major proteases of the periodontal pathogen Porphyromonas gingivalis. The casein peptides αS1-casein (11–23), β-casein (193–209), κ-casein (106–169) and κ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc567644e3d6114d12cacd46851c080f
https://doi.org/10.1016/j.idairyj.2011.12.009
https://doi.org/10.1016/j.idairyj.2011.12.009