Zobrazeno 1 - 10
of 38
pro vyhledávání: '"N L Young"'
Publikováno v:
Journal of Lipid Research, Vol 23, Iss 6, Pp 831-838 (1982)
Rats with streptozotocin-induced diabetes stop growing, develop high cholesterol and triacylglycerol levels in plasma, and have decreased activity of the rate-limiting enzyme in cholesterol synthesis, 3-hydroxy-3-methylglutaryl CoA reductase (EC 1.1.
Externí odkaz:
https://doaj.org/article/5d6d52f58c1e4789aae3c73dc8d8a162
Publikováno v:
Journal of Lipid Research, Vol 23, Iss 2, Pp 266-275 (1982)
We examined the effect of streptozotocin-induced diabetes on the rate-limiting enzyme in cholesterol synthesis, 3-hydroxy-3-methylglutaryl CoA reductase (EC 1.1.1.34), in liver and small intestine of rats. During the acute phase of insulin deficiency
Externí odkaz:
https://doaj.org/article/fee710bf77cb4b5eace4a118a55095f6
Publikováno v:
Journal of Lipid Research, Vol 23, Iss 2, Pp 257-265 (1982)
We describe a method for estimating the total activity of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase (EC 1.1.1.34) in the small intestine of rats. An homogenate of the whole small intestine is prepared rapidly and assayed directly to maximize
Externí odkaz:
https://doaj.org/article/6131656a82cb413f8a8eb75ede7ab392
Autor:
N L Young, V W Rodwell
Publikováno v:
Journal of Lipid Research, Vol 18, Iss 5, Pp 572-581 (1977)
Methods were developed for the assay of hydroxymethylglutaryl-CoA reductase (NADPH) activity in microsomes from rat leukocytes. The activity in freshly isolated leukocytes is low compared to rat liver but can be assayed reliably. The patterns of resp
Externí odkaz:
https://doaj.org/article/8b9353c993644929ac90aa298e926610
Publikováno v:
Journal of Lipid Research, Vol 26, Iss 1, Pp 62-69 (1985)
The contribution of dietary cholesterol to hypercholesterolemia in diabetic rats fed chow ad libitum was evaluated. Diabetes was induced with streptozotocin, and the intake, absorption, and subsequent tissue distribution of dietary cholesterol were m
Externí odkaz:
https://doaj.org/article/d02bbad596b946e39d7c5a5b7e138500
Autor:
J Elovson, J E Chatterton, G T Bell, V N Schumaker, M A Reuben, D L Puppione, J R Reeve, Jr, N L Young
Publikováno v:
Journal of Lipid Research, Vol 29, Iss 11, Pp 1461-1473 (1988)
Rat and human very low density lipoproteins (VLDL) were fractionated by zonal ultracentrifugation, yielding sharply defined fractions with narrow sedimentation limits. Sedimentation coefficients for the individual fractions were determined at two den
Externí odkaz:
https://doaj.org/article/35970fede42a4ea69d1bc490cee69b43
Publikováno v:
Rural and remote health. 14
Aboriginal people in Canada (First Nations, Inuit and Métis) have a lower health status compared to the Canadian population. There is a particular concern about the mental health and wellbeing of First Nations adolescents living on reserves. Interve
Autor:
J. D. Grainger, N. L. Young, V. S. Blanchette, R. J. Klaassen, V. E. Price, P. H. B. Bolton-Maggs, C. Curtis, C. Wakefield, T. A. Burke, G. Dufort, G. Gaedicke, A. Riedlinger, C. Soltner, E. Citrin, Y. Reguerre, I. Pellier, C. E. Neunert, G. R. Buchanan
Publikováno v:
Archives of disease in childhood. 98(11)
Objective To determine the impact of therapy on the reported health-related quality of life (HRQoL) in children with primary immune thrombocytopenia (ITP) using the Kids ITP tool (KIT). Design Secondary data analysis of the international and North Am
Autor:
L, Aledort, M, Bullinger, S, von Mackensen, J, Wasserman, N L, Young, D, Globe, Manuel, Carcao
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 18(3)
The very high cost of haemophilia care, including the increase in use of factor prophylaxis in both children and adults requires that funders of clotting factor concentrates require objective measures of health, such as joint status and quality of li
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 18(3)
Multi-site studies are necessary in the field of haemophilia to ensure adequate sample sizes. Quality of life (QoL) instruments need to be harmonized across languages and cultures to facilitate their inclusion. The purpose of this study was to adapt