Zobrazeno 1 - 10
of 80
pro vyhledávání: '"N L Vujanovic"'
Publikováno v:
Interleukin-2 and Killer Cells in Cancer ISBN: 9781351073790
Stimulation of peripheral blood or splenic lymphocytes with interleukin-2 (IL-2) induces several responses, including adherence of LGL/NK cells to plastic surfaces, augmentation of NK cell cytolytic function, induction of lymphokine activated killer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27922294cfaafebcfd3d98f0b6b43302
https://doi.org/10.1201/9781351073790-23
https://doi.org/10.1201/9781351073790-23
Autor:
Shigeki Nagashima, Yoshinori Suminami, K Hirabayashi, N L Vujanovic, H Kato, Theresa L. Whiteside
Publikováno v:
British Journal of Cancer
The squamous cell carcinoma antigen (SCC Ag) is a tumour-associated protein and a member of theserineproteaseinhibitor (serpin) family. The SCC Ag has been used as a serologic tumour marker for SCC progression, and its elevated serum levels are a ris
Publikováno v:
The Journal of Immunology. 157:1117-1126
We defined a novel constitutive mechanism of cell-mediated cytotoxicity, utilized by nonactivated human peripheral blood NK cells against a variety of tumor cell targets resistant to secretory (i.e., perforin/granzyme-mediated) NK cell killing. Untre
Autor:
N L Vujanovic, L Polimeno, A Azzarone, A Francavilla, W H Chambers, T E Starzl, R B Herberman, T L Whiteside
Publikováno v:
The Journal of Immunology. 154:6324-6338
To determine the role of NK cells in regulation of tissue growth, the phenotype and function of liver-resident NK cells were studied after 70% partial hepatectomy in rats. The process of liver regeneration was generally completed by day 14. In contra
Publikováno v:
Neoplasma. 48(3)
This study was performed to investigate functional properties of mononuclear phagocytes isolated from ascitic fluid in patients with peritoneal carcinomatosis (PC), and potential immunomodulatory effects of soluble factors produced or induced by huma
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(6)
The generation and activity of NK cells appear to be regulated by a particular set of cytokines. We examined the in vivo effects of recombinant human Flt3 ligand (Flt3-L), a recently cloned potent hemopoietic cytokine, on NK cell development in mice.
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(5)
Human antitumor effector cells include class I major histocompatibility complex (MHC)-restricted T cells and non-MHC-restricted natural killer (NK) cells. These two types of effector cells have not been directly compared for the ability to eliminate
Publikováno v:
Current topics in microbiology and immunology. 230
Evidence has been reviewed which indicates that NK cells play a role in the control of metastasis dissemination. Both activation of endogenous NK cells in a tumor-bearing host and adoptive transfer of ex vivo activated NK cells may be therapeutically
Publikováno v:
European journal of immunology. 28(3)
Recent studies have suggested that B7-CD28 interactions provide co-stimulatory signals for activation of NK cells. Transduction of the B7.1 (CD80) gene into tumor cells has been shown to trigger proliferation and cytotoxicity of murine NK cells and a
Publikováno v:
Cancer research. 56(7)
An in vivo model of liver metastasis induced by human gastric carcinoma was established in nude mice and used for locoregional or systemic immunotherapy with a subset of human A-natural killer (NK) cells defined previously. A single intrasplenic (i.s