Zobrazeno 1 - 8
of 8
pro vyhledávání: '"N L McCartney-Francis"'
Autor:
N L McCartney-Francis, D E Mizel, R S Redman, M Frazier-Jessen, R B Panek, A B Kulkarni, J M Ward, J B McCarthy, S M Wahl
Publikováno v:
The Journal of Immunology. 157:1306-1312
The targeted disruption of the TGF-beta1 gene in mice (TGF-beta1 -/-) leads to extensive inflammation in vital organs, cachexia, and death within 3 to 4 wk. Significant inflammatory lesions develop initially in the periductal regions of the salivary
Autor:
M Christ, N L McCartney-Francis, A B Kulkarni, J M Ward, D E Mizel, C L Mackall, R E Gress, K L Hines, H Tian, S Karlsson
Publikováno v:
The Journal of Immunology. 153:1936-1946
Approximately 2 wk after birth, mice having a TGF-beta 1 null mutation (TGF-beta 1(-/-)) exhibit a progressive wasting syndrome and death. Associated with this phenotype is a multifocal infiltration of lymphocytes and macrophages into target organs,
Publikováno v:
Arthritis and rheumatism. 42(6)
To investigate the ability of hemoglobin (Hgb), a nitric oxide (NO) scavenger, to deplete excess NO and reduce inflammation and injury in synovial tissue from joints with inflammatory arthritis.The severity of streptococcal cell wall-induced arthriti
Publikováno v:
International reviews of immunology. 16(5-6)
Regulation of developmental processes as well as host defense and repair mechanisms requires the maintenance of a delicate balance of positive and negative regulatory signals. TGF-beta, a molecule known for its many diverse activities, can promote or
Autor:
N L, McCartney-Francis, D E, Mizel, M, Frazier-Jessen, A B, Kulkarni, J B, McCarthy, S M, Wahl
Publikováno v:
The American journal of pathology. 151(5)
Mice homozygous for a nonfunctional transforming growth factor-beta 1 gene develop rampant inflammation in vital organs that contributes to a shortened life span. The presence of circulating anti-nuclear anti-bodies, immune deposits in tissues, leuko
Autor:
N L, McCartney-Francis, D E, Mizel, R S, Redman, M, Frazier-Jessen, R B, Panek, A B, Kulkarni, J M, Ward, J B, McCarthy, S M, Wahl
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 157(3)
The targeted disruption of the TGF-beta1 gene in mice (TGF-beta1 -/-) leads to extensive inflammation in vital organs, cachexia, and death within 3 to 4 wk. Significant inflammatory lesions develop initially in the periductal regions of the salivary
Autor:
M, Christ, N L, McCartney-Francis, A B, Kulkarni, J M, Ward, D E, Mizel, C L, Mackall, R E, Gress, K L, Hines, H, Tian, S, Karlsson
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 153(5)
Approximately 2 wk after birth, mice having a TGF-beta 1 null mutation (TGF-beta 1(-/-)) exhibit a progressive wasting syndrome and death. Associated with this phenotype is a multifocal infiltration of lymphocytes and macrophages into target organs,
Publikováno v:
Journal of molecular evolution. 25(4)
New insights into the evolution of the families of genes encoding immunoglobulins and T-cell receptors of rabbits (Oryctolagus cuniculus) have come from molecular genetic studies. In contrast to human and mouse, rabbits were shown to have two genes f