Zobrazeno 1 - 8
of 8
pro vyhledávání: '"N L Krett"'
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(10)
Multiple myeloma is a neoplastic proliferation of plasma cells. Glucocorticoids are among the most effective agents against multiple myeloma, acting through the glucocorticoid receptor to induce programmed cell death. However, some patients do not re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7e4f5801b3fb2f16c0b3a13b8a9ca9d
https://pubmed.ncbi.nlm.nih.gov/9815564
https://pubmed.ncbi.nlm.nih.gov/9815564
Publikováno v:
Blood. 92(8)
We have examined the cytotoxic effects of cyclic adenosine-3', 5'-monophosphate (cAMP) derivatives on multiple myeloma cells lines and determined that the 8-Chloro substituted derivative (8Cl-cAMP) is one of the most potent. We report here that 8Cl-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62712063a75b38b897d07c1bd2149500
https://pubmed.ncbi.nlm.nih.gov/9763575
https://pubmed.ncbi.nlm.nih.gov/9763575
Publikováno v:
Endocrinology. 136(9)
Rat decidual tissue is formed by two distinct decidual cell populations located either antimesometrially or mesometrially in the uterus. They differ in morphology, the genes they express, the proteins they secrete, and the role they play during pregn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b094f7b2ab50cd1a09104305172eabae
https://pubmed.ncbi.nlm.nih.gov/7544272
https://pubmed.ncbi.nlm.nih.gov/7544272
Publikováno v:
Cancer research. 55(13)
In multiple myeloma cells resistant to glucocorticoids, we have previously identified a variant glucocorticoid receptor (GR) transcript (P. A. Moalli et al., Cancer Res., 53: 3877-3879, 1993). Here, we report a reverse transcription-PCR assay to asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65712e572bac9a58b538d3fe473bab25
https://pubmed.ncbi.nlm.nih.gov/7796394
https://pubmed.ncbi.nlm.nih.gov/7796394
Publikováno v:
Cancer research. 53(17)
Glucocorticoids are highly effective chemotherapeutic agents used in the treatment of hematological malignancies including multiple myeloma. However, the clinical usefulness of this class of drugs is limited by the problem of resistance. In the follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::240be0adfca50707d931b927fe67e66c
https://pubmed.ncbi.nlm.nih.gov/8358712
https://pubmed.ncbi.nlm.nih.gov/8358712
Autor:
M L, Graham, N L, Krett, L A, Miller, K K, Leslie, D F, Gordon, W M, Wood, L L, Wei, K B, Horwitz
Publikováno v:
Cancer research. 50(19)
We postulate that one mechanism for the progression of breast cancers to hormone resistance involves the acquisition of mutant estrogen receptors (ER)4 by genetically unstable cell subpopulations. The T47D human breast cancer cell line may be a model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0703fb8f9382cf0b8913fa4b9d297f17
https://pubmed.ncbi.nlm.nih.gov/2400987
https://pubmed.ncbi.nlm.nih.gov/2400987
Publikováno v:
Progress in clinical and biological research. 322
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c96a79ff225bf713abfeeee048cff7f5
https://pubmed.ncbi.nlm.nih.gov/2406737
https://pubmed.ncbi.nlm.nih.gov/2406737
Publikováno v:
The Journal of biological chemistry. 259(4)
We have reported previously that insulin causes a complete but reversible desensitization to insulin action in rat hepatoma HTC cells in tissue culture, and that this insulin resistance is mediated by postbinding mechanisms rather than receptor down-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64db4e962710eff723dceb15f037c58a
https://pubmed.ncbi.nlm.nih.gov/6142041
https://pubmed.ncbi.nlm.nih.gov/6142041