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Prognostic factors for atherosclerosis progression in saphenous vein grafts: the postcoronary artery bypass graft (Post-CABG) trial. Post-CABG Trial Investigators

Autor: M J, Domanski, C B, Borkowf, L, Campeau, G L, Knatterud, C, White, B, Hoogwerf, Y, Rosenberg, N L, Geller

Publikováno v: Journal of the American College of Cardiology. 36(6)

The study was done to assess patients in the Post-Coronary Artery Bypass Graft (Post-CABG) trial to determine prognostic factors for atherosclerosis progression.Saphenous vein grafts (SVGs) are effective in relieving angina and, in certain patient su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6eb65ffc2755a3f9fb6c25581319897f
https://pubmed.ncbi.nlm.nih.gov/11092659

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Fraud in medical research: an international survey of biostatisticians. ISCB Subcommittee on Fraud

Autor: J, Ranstam, M, Buyse, S L, George, S, Evans, N L, Geller, B, Scherrer, E, Lesaffre, G, Murray, L, Edler, J L, Hutton, T, Colton, P, Lachenbruch

Publikováno v: Controlled clinical trials. 21(5)

The characteristics of scientific fraud and its impact on medical research are in general not well known. However, the interest in the phenomenon has increased steadily during the last decade. Biostatisticians routinely work closely with physicians a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::232f59822ec7760246cefcf66e09580a
https://pubmed.ncbi.nlm.nih.gov/11436842

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The role of biostatistics in the prevention, detection and treatment of fraud in clinical trials

Autor: M, Buyse, S L, George, S, Evans, N L, Geller, J, Ranstam, B, Scherrer, E, Lesaffre, G, Murray, L, Edler, J, Hutton, T, Colton, P, Lachenbruch, B L, Verma

Publikováno v: Statistics in medicine. 18(24)

Recent cases of fraud in clinical trials have attracted considerable media attention, but relatively little reaction from the biostatistical community. In this paper we argue that biostatisticians should be involved in preventing fraud (as well as un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf328fb344248a6a61ee98ab473570aa
https://pubmed.ncbi.nlm.nih.gov/10611617

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Effect of angiotensin converting enzyme inhibition on sudden cardiac death in patients following acute myocardial infarction. A meta-analysis of randomized clinical trials

Autor: M J, Domanski, D V, Exner, C B, Borkowf, N L, Geller, Y, Rosenberg, M A, Pfeffer

Publikováno v: Journal of the American College of Cardiology. 33(3)

Estimate the effect of angiotensin converting enzyme (ACE) inhibitors on the risk of sudden cardiac death (SCD) following myocardial infarction (MI).Trials in post-MI patients have shown that ACE inhibitor therapy reduces mortality. However, the effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9fb602d70e8477fd385be64e87fae81d
https://pubmed.ncbi.nlm.nih.gov/10080457

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Behavioral and pharmacologic interventions: the Raynaud's Treatment Study

Autor: B, Thompson, N L, Geller, S, Hunsberger, M, Frederick, R, Hill, R G, Jacob, E A, Smith, P, Kaufmann, R R, Freedman, F M, Wigley, L, Bielory

Publikováno v: Controlled clinical trials. 20(1)

The Raynaud's Treatment Study (RTS) exemplified clinical trials with treatments that differ qualitatively both in their modes and in their methods of delivery. The RTS compared finger-temperature biofeedback to slow-release nifedipine, a calcium chan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7de24ff310c7ff117b6de35bbed03801
https://pubmed.ncbi.nlm.nih.gov/10027500

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Anginal status and prediction of cardiac events in patients enrolled in the asymptomatic cardiac ischemia pilot (ACIP) study. ACIP investigators

Autor: C R, Conti, N L, Geller, G L, Knatterud, S A, Forman, C M, Pratt, C J, Pepine, G, Sopko

Publikováno v: The American journal of cardiology. 79(7)

We hypothesized that among the patients enrolled in the Asymptomatic Cardiac Ischemia Pilot (ACIP) trial, those who reported angina either within the previous 6 weeks or experienced angina during ambulatory electrocardiographic (ECG) monitoring durin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::095c139973cc1f7aaf118f8d95ca0093
https://pubmed.ncbi.nlm.nih.gov/9104900

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Ischemia during ambulatory monitoring as a prognostic indicator in patients with stable coronary artery disease

Autor: D, Mulcahy, S, Husain, G, Zalos, A, Rehman, N P, Andrews, W H, Schenke, N L, Geller, A A, Quyyumi

Publikováno v: JAMA. 277(4)

To assess long-term prognostic significance of transient ischemia in patients with documented coronary artery disease and stable symptoms and to examine the relation between transient ischemia and the site of angiographic disease progression followin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aab0e11981b0e4cf3a79bd7e5eb1b287
https://pubmed.ncbi.nlm.nih.gov/9178784

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Diabetics with coronary disease have a prevalence of asymptomatic ischemia during exercise treadmill testing and ambulatory ischemia monitoring similar to that of nondiabetic patients. An ACIP database study. ACIP Investigators. Asymptomatic Cardiac Ischemia Pilot Investigators

Autor: E A, Caracciolo, B R, Chaitman, S A, Forman, P H, Stone, M G, Bourassa, G, Sopko, N L, Geller, C R, Conti

Publikováno v: Circulation. 93(12)

There are conflicting data as to whether diabetics have a higher prevalence of asymptomatic ST-segment depression during exercise treadmill testing (ETT) and ambulatory ECG (AECG) monitoring. This study was conducted to determine whether diabetic pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e18ae566d3e477e7c6e1358f55159ec5
https://pubmed.ncbi.nlm.nih.gov/8925575

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Monitoring pairwise comparisons in multi-armed clinical trials

Autor: D A, Follmann, M A, Proschan, N L, Geller

Publikováno v: Biometrics. 50(2)

This paper proposes a method for monitoring multi-armed clinical trials on the basis of pairwise comparisons between arms. The set of pairwise test statistics is examined during the course of the trial in order to make decisions about hypotheses, con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6a44f6403c5bc788cd603132a61a4f4d
https://pubmed.ncbi.nlm.nih.gov/8068834

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