Zobrazeno 1 - 10
of 10
pro vyhledávání: '"N L, Saccone"'
Autor:
D B, Hancock, Y, Guo, G W, Reginsson, N C, Gaddis, S M, Lutz, R, Sherva, A, Loukola, C C, Minica, C A, Markunas, Y, Han, K A, Young, D F, Gudbjartsson, F, Gu, D W, McNeil, B, Qaiser, C, Glasheen, S, Olson, M T, Landi, P A F, Madden, L A, Farrer, J, Vink, N L, Saccone, M C, Neale, H R, Kranzler, J, McKay, R J, Hung, C I, Amos, M L, Marazita, D I, Boomsma, T B, Baker, J, Gelernter, J, Kaprio, N E, Caporaso, T E, Thorgeirsson, J E, Hokanson, L J, Bierut, K, Stefansson, E O, Johnson
Publikováno v:
Molecular psychiatry
Cigarette smoking is a leading cause of preventable mortality worldwide. Nicotine dependence, which reduces the likelihood of quitting smoking, is a heritable trait with firmly established associations with sequence variants in nicotine acetylcholine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2197a9a583fbe8e39be1019a8da2323
https://pubmed.ncbi.nlm.nih.gov/28972577
https://pubmed.ncbi.nlm.nih.gov/28972577
Publikováno v:
Genetic epidemiology. 19
Here we focus on using clustering methods to disentangle the interacting factors that lead to the presentation of complex diseases. Relative pairs are placed in discrete subgroups, or classes, based upon their pattern of allele sharing at a sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a1a12d8e269d701c61f9bee382e7e9f
https://pubmed.ncbi.nlm.nih.gov/11055371
https://pubmed.ncbi.nlm.nih.gov/11055371
Autor:
N L, Saccone, J M, Kwon, J, Corbett, A, Goate, N, Rochberg, H J, Edenberg, T, Foroud, T K, Li, H, Begleiter, T, Reich, J P, Rice
Publikováno v:
American journal of medical genetics. 96(5)
The Collaborative Study on the Genetics of Alcoholism (COGA) is a multicenter research program to detect and map susceptibility genes for alcohol dependence and related phenotypes. The measure M of "maximum number of drinks consumed in a 24-hour peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa8f62129e92156015ad56d0a22c62e5
https://pubmed.ncbi.nlm.nih.gov/11054770
https://pubmed.ncbi.nlm.nih.gov/11054770
Publikováno v:
Advances in genetics. 42
Definition of the phenotype is a key issue in designing any genetic study whose goal is to detect disease genes. This chapter describes strategies to increase the power to detect susceptibility loci for complex diseases. A narrowly defined disease ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05b3df249a3ebe20982cd4467961a4e0
https://pubmed.ncbi.nlm.nih.gov/11037314
https://pubmed.ncbi.nlm.nih.gov/11037314
Publikováno v:
Advances in genetics. 42
The lod score method originated in a seminal article by Newton Morton in 1955. The method is broadly concerned with issues of power and the posterior probability of linkage, ensuring that a reported linkage has a high probability of being a true link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77e744ab32e292599f5221b153fad10b
https://pubmed.ncbi.nlm.nih.gov/11037316
https://pubmed.ncbi.nlm.nih.gov/11037316
Publikováno v:
Genetic epidemiology. 17
We model functions that use genetic information as input and trait information as output to understand genetic linkage in complex diseases. Using simulated data from GAW11, we have applied categorical classification methods and neural network analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7581b7b46fb8557d4b95ff831c933742
https://pubmed.ncbi.nlm.nih.gov/10597517
https://pubmed.ncbi.nlm.nih.gov/10597517
Publikováno v:
Genetic epidemiology. 17
We apply a novel technique to detect significant covariates in linkage analysis using a logistic regression approach. An overall test of linkage is first performed to determine whether there is significant perturbation from the expected 50% sharing u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd2daa9d98d9e8853ccd2237ae919b7f
https://pubmed.ncbi.nlm.nih.gov/10597515
https://pubmed.ncbi.nlm.nih.gov/10597515
Autor:
N L, Saccone, J P, Rice, N, Rochberg, A, Goate, T, Reich, S, Shears, W, Wu, J I, Nurnberger, T, Foroud, H J, Edenberg, T K, Li
Publikováno v:
American journal of medical genetics. 88(5)
To identify loci involved in the control of platelet monoamine oxidase B (MAO-B) activity, a genomewide linkage screen was performed using 291 markers in 148 nuclear families containing a total of 1,008 nonindependent sib-pairs. Participants were gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96dbf21cec93689bc94e81b39961b206
https://pubmed.ncbi.nlm.nih.gov/10490709
https://pubmed.ncbi.nlm.nih.gov/10490709
Autor:
J. Corbett, N. L. Saccone, T. Foroud, A. Goate, H. Edenberg, J. Nurnberger, B. Porjesz, H. Begleiter, T. Reich, J. P. Rice
Publikováno v:
Psychiatric Genetics; Mar2005, Vol. 15 Issue 1, p25-30, 6p
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