Zobrazeno 1 - 10
of 14
pro vyhledávání: '"N L, Ronzhina"'
Autor:
S. N. Naryzhny, V. G. Zgoda, M. A. Maynskova, N. L. Ronzhina, N. V. Belyakova, O. K. Legina, A. I. Archakov
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 9:305-311
Autor:
S. N. Naryzhny, N. L. Ronzhina, M. A. Mainskova, N. V. Belyakova, R. A. Pantina, M. V. Filatov
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 8:243-251
Publikováno v:
Cell and Tissue Biology. 4:424-428
Mutations in genes of DNA polymerases or corrective 3′ → 5′-exonucleases lead to a decrease in the fidelity of DNA biosynthesis throughout the genome, which is accompanied by an increase in the probability of mutagenesis and carcinogenesis. In
Publikováno v:
Biology Bulletin. 37:464-470
The possibility of interaction of recombinant proteins of human repair DNA polymerase β with proofreading 3′ → 5′-exonucleases TREX1 and TREX2 was investigated in vitro for the first time. The results of gel filtration analysis show the format
Autor:
O. K. Legina, N. V. Belyakova, T. P. Kravetskaya, N. L. Ronzhina, V. M. Krutyakov, I. V. Shevelev
Publikováno v:
Biology Bulletin. 34:427-433
The complexes of repair DNA polymerase β with 3′-exonuclease and some other proteins were isolated from the chromatin of hepatocytes of normal rats for the first time. Biopolymers were extracted from the chromatin by the solution of NaCl and Trito
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 38:161-168
Recently we have revealed a high content of autonomous 3"→5" exonucleases (AE), i.e., those not bound covalently with DNA polymerases, in cells of vertebrates, from fish to human [1]. In the present work, using gel filtration method, cell-free extr
Autor:
M. V. Filatov, N. V. Belyakova, R. A. Pantina, N. L. Ronzhina, Stanislav N. Naryzhny, M. A. Mainskova
Publikováno v:
Biomeditsinskaia khimiia. 60(3)
High grade glioma (glioblastoma) is the most common brain tumor. Its malignancy makes it the fourth biggest cause of cancer death. In our experiments we used several glioblastoma cell lines generated in our laboratory to obtain proteomics information
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 36:262-266
Using methods of gel filtration and ultracentrifugation, cell-free extracts from 12 objects representing the main vertebrate representatives (bony fish, amphibian, reptiles, birds, mammals, including human) were studied. The enzyme activity of autono
Publikováno v:
Izvestiia Akademii nauk. Seriia biologicheskaia. (5)
The possibility of interaction of recombinant proteins of human repair DNA polymerase beta with proofreading 3' --5'-exonucleases TREX1 and TREX2 was investigated in vitro for the first time. The results of gel filtration analysis show the formation
Publikováno v:
Tsitologiia. 52(8)
Mutations in the genes of corrective 3' --5'-exonucleases as well as in DNA polymerases lead to decrease in DNA biosynthesis accuracy all over genome. This is accompanied by the increase in mutagenesis and carcinogenesis probabilities. In this work,