Zobrazeno 1 - 10
of 25
pro vyhledávání: '"N K, Vlasenkova"'
Autor:
O. V. Goryunova, G. N. Apryshko, L. V. Fetisova, R. B. Pugacheva, O. S. Zhukova, N. K. Vlasenkova
Publikováno v:
Russian Journal of Biotherapy. 16:46-54
Objective: to evaluate the prospects of the glycosides of indolocarbazole containing amino acid residues as potential antitumor compounds. Materials and methods. For 32 compounds by structural formulas using the methods of chemoinformatics, a number
Publikováno v:
Russian Journal of Biotherapy. 15:70-78
Background. Concentration of a prostate specific antigen (PSA) in blood serum considerably increases in case of development of a prostate adenocarcinoma, in tens and hundreds times exceeding extreme values of the range of the determined concentration
Autor:
G. K. Gerasimova, Sergey G. Klochkov, S. V. Afanas’eva, Yu. N. Bulychev, A. N. Pushin, N. K. Vlasenkova
Publikováno v:
Chemistry of Natural Compounds. 45:817-823
Previously unknown amino-derivatives of the natural sesquiterpene lactone α-santonin were synthesized. The activity of the products against several human tumor-cell lines was studied.
Autor:
A.P. Kaplun, V. I. Shvets, E L Surkova, A. V. Symon, N. K. Vlasenkova, G. K. Gerasimova, E F Litvin, L M Kozlova, Le Bang Shon
Publikováno v:
Russian Journal of Bioorganic Chemistry. 29:185-189
Two methods of obtaining of 3 alpha-betulinic acid and related compounds from their 3 beta-epimers were studied: the reaction of bimolecular substitution and the stereoselective reduction of 3-ketoderivatives. The substitution of acyloxy by formyloxy
Publikováno v:
Pharmaceutical Chemistry Journal. 30:213-216
Publikováno v:
Vestnik Rossiiskoi akademii meditsinskikh nauk. (10)
A4 clone cells, received by CD95-mediated selection from the parental line of Jurkat T-lymphoblast human leukosis, lost their ability of apoptosis as a result of programmed cell death mechanism breakdown. The complex of their acquired phenotypic prop
Autor:
A.P. Kaplun, G. K. Gerasimova, V. I. Shvets, N. N. Veselova, A. V. Symon, A. I. Lyutik, G. A. Fedorova, N. K. Vlasenkova
Publikováno v:
Bioorganicheskaia khimiia. 31(3)
New cyclopropane derivatives of betulin were synthesized by attachment of dichlorocarbenes or dibromocarbenes to the double bond of betulin diacetate, followed by the deprotection of hydroxyl groups. The betulin cyclopropane derivative was obtained f
Autor:
A V, Symon, A P, Kaplun, N K, Vlasenkova, G K, Gerasimova, Le Bang, Shon, E F, Litvin, L M, Kozlova, E L, Surkova, V I, Shvets
Publikováno v:
Bioorganicheskaia khimiia. 29(2)
Two methods of obtaining of 3 alpha-betulinic acid and related compounds from their 3 beta-epimers were studied: the reaction of bimolecular substitution and the stereoselective reduction of 3-ketoderivatives. The substitution of acyloxy by formyloxy
Autor:
A. V. Symon, N. N. Veselova, A.P. Kaplun, N. K. Vlasenkova, G. A. Fedorova, A. I. Lyutik, G. K. Gerasimova, V. I. Shvets
Publikováno v:
Russian Journal of Bioorganic Chemistry; May2005, Vol. 31 Issue 3, p286-291, 6p
Publikováno v:
European Journal of Cancer Supplements. 1:S294-S295