Zobrazeno 1 - 10 of 72 pro vyhledávání: '"N K, Maclaren"'
2
Medical care from childhood to adulthood in Type 1 and Type 2 diabetes
Autor: N. K. Maclaren, S. Ten, Giulia Costi
Publikováno v: Journal of Endocrinological Investigation. 24:692-707
Diabetes mellitus comprises a heterogeneous group of diseases that have in common the development of macro- and microvascular complications. It is now possible to identify subjects at high risk of Type 1 or Type 2 diabetes, especially in the patient'
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d9007538ecd9be3e83308f88221f6c
https://doi.org/10.1007/bf03343914
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3
Current cases in which epitope mimicry is considered as a component cause of autoimmune disease: immune-mediated (type 1) diabetes
Autor: A. Kukreja, N. K. Maclaren
Publikováno v: Cellular and Molecular Life Sciences. 57:534-541
Autoimmune diseases result from a combination of genetic, immunologic, hormonal, and environmental factors. Infectious agents may induce the breakdown of immunological tolerance and the appearance of autoreactivity. However, the specific relationship
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19f2c3ee4556e2272c1ce26fc5481a6
https://doi.org/10.1007/pl00000715
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4
Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcription
Autor: N K Maclaren, Andrew Muir, Roberto Luchetta, Jeffrey P. Krischer, Janet G. Cornelius, Ammon B. Peck, Michael J. Clare-Salzler, Yao-Hua Song
Publikováno v: Journal of Clinical Investigation. 95:628-634
We reported previously that daily injections of isophane insulin prevented both hyperglycemia and insulitis in nonobese diabetic (NOD) mice (Atkinson, M., N. Maclaren; and R. Luchetta. 1990. Diabetes. 39:933-937). The possible mechanisms responsible
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123be05b92188baefa2de714d235cbc5
https://doi.org/10.1172/jci117707
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5
The role of tyrosinase in autoimmune vitiligo
Autor: Balducci P, Yangxin Li, Yao-Hua Song, N K Maclaren, Barbara Zorovich, Ellen L. Connor
Publikováno v: The Lancet. 344:1049-1052
Vitiligo is a common depigmenting skin disease, associated with certain autoimmune endocrinopathies, and autoantibodies to several antigens can be found in melanoma cells. We set out to identify the antigens. We examined 26 patients with vitiligo and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23f8e30a6304548ae30fc4429b4aad4
https://doi.org/10.1016/s0140-6736(94)91709-4
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8
No evidence for serological autoimmunity to islet cell heat shock proteins in insulin dependent diabetes
Autor: L A Holmes, Mark A. Atkinson, Paul E. Lacy, N K Maclaren, David W. Scharp
Publikováno v: Journal of Clinical Investigation. 87:721-724
Recent studies in nonobese diabetic mice have implicated the autoimmune destruction of pancreatic islet cells with immunity to a beta cell protein cross-reactive to Mycobacterium tuberculosis heat shock protein 65 (hsp 65). Therefore, our studies exa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73f3381c3805ad97d36d3669cd35780
https://doi.org/10.1172/jci115051
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