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pro vyhledávání: '"N K, Hollenberg"'
Autor:
N K, Hollenberg
Publikováno v:
Current hypertension reports. 3
When angiotensin-converting enzyme (ACE) inhibition first became available to block the renin system, few could have predicted the evolution that would occur in this field. The advent of angiotensin II receptor 1 (AT(1)) blockers has created new oppo
Autor:
N K, Hollenberg
Publikováno v:
Current hypertension reports. 3(3)
Autor:
N K, Hollenberg
Publikováno v:
Blood pressure. Supplement. 1
Suppression of the renin-angiotensin system (RAS) with angiotensin-converting enzyme (ACE) inhibitors is an established method for controlling blood pressure and reducing the risk of cardiovascular disease. In addition to reducing blood pressure, sup
Autor:
N K, Hollenberg
Publikováno v:
Blood pressure monitoring. 4
We have known for 70 years that familial factors influence blood pressure level. Modern genetics suggest that 30-40% of blood pressure variation reflects genetic factors. We have known for more than 40 years that patients differ in their response to
Publikováno v:
American journal of hypertension. 12(4 Pt 1)
We have recently reported a combination of renal features that suggests independent angiotensin-mediated control of the renal circulation in the majority of hypertensive patients with type II diabetes. To ascertain whether other tissue elements of th
Autor:
N K, Hollenberg
Publikováno v:
Pharmacotherapy. 19(4 Pt 2)
Autor:
N K, Hollenberg
Publikováno v:
Journal of the American Society of Nephrology : JASN. 10
Pharmacologic interruption of the renin-angiotensin system has played a crucial role in determining its contribution to physiology, pathophysiology, and has made an enormous contribution to therapeutics. Despite this record of success, no pharmacolog
Autor:
N K, Hollenberg
Publikováno v:
Journal of hypertension. Supplement : official journal of the International Society of Hypertension. 15(7)
Renal protective effects in diabetic patients. Blocking the renin-angiotensin system slows the progression of nephropathy and end-stage renal disease in diabetes mellitus. While substantial evidence exists for the renal protective effects of angioten
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(2)
To compare the effects of a potent rat renin inhibitor peptide (RIP) and angiotensin-converting enzyme (ACE) inhibitor on the intrarenal and plasma renin-angiotensin systems, anesthetized Sprague-Dawley rats were treated with an infusion of vehicle,
Autor:
N K, Hollenberg, S W, Graves
Publikováno v:
Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques. 46
One might ask, given the number of false trails that have been pursued, why we, and so many others, have continued to pursue the elusive digitalis-like factor? The answer can be found in the many review articles cited above [4-13]. In animal models o