Zobrazeno 1 - 10 of 53 pro vyhledávání: '"N K, Damle"'
1
Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7
Autor: N K Damle, K Klussman, G Leytze, S Myrdal, A Aruffo, J A Ledbetter, P S Linsley
Publikováno v: The Journal of Immunology. 152:2686-2697
Costimulation by the CD28 ligand B7/BB1 plays an important role during T cell proliferation primarily by augmenting synthesis of IL-2 and other cytokines. Resting CD4+ T cells express CD28 but not CTLA-4 on their surface. Costimulation of T cells wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d204e07cd394e1db2e278c788b0cb5f2
https://doi.org/10.4049/jimmunol.152.6.2686
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2
Costimulation with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 augments activation-induced death of antigen-specific CD4+ T lymphocytes
Autor: N K Damle, K Klussman, G Leytze, A Aruffo, P S Linsley, J A Ledbetter
Publikováno v: The Journal of Immunology. 151:2368-2379
Integrin ligands intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) can efficiently costimulate proliferation of resting T cells but not that of Ag-specific T cells. In contrast, CD28 ligand B7 and CD2 ligand le
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::615c351d55ac5140555bbd961bfdde2e
https://doi.org/10.4049/jimmunol.151.5.2368
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3
Intercellular adhesion molecule-2, a second counter-receptor for CD11a/CD18 (leukocyte function-associated antigen-1), provides a costimulatory signal for T-cell receptor-initiated activation of human T cells
Autor: N K Damle, K Klussman, A Aruffo
Publikováno v: The Journal of Immunology. 148:665-671
Activation of T cells often requires both activation signals delivered by ligation of the TCR and those resulting from costimulatory interactions between certain T cell surface accessory molecules and their respective counter-receptors on APC. CD11a/
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f84d0c49f74f1ed4d0a8ec79f29ba3c9
https://doi.org/10.4049/jimmunol.148.3.665
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4
Ability of human T lymphocytes to adhere to vascular endothelial cells and to augment endothelial permeability to macromolecules is linked to their state of post-thymic maturation
Autor: N K Damle, L V Doyle
Publikováno v: The Journal of Immunology. 144:1233-1240
The accumulation of mononuclear cells at sites of chronic inflammation is dependent on a number of factors including localized adherence of lymphocytes to vascular endothelial cells (EC), cytokine-mediated increased adhesiveness of endothelium, chemo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f505a2b1b51b8bf0a562803b5ce3c64
https://doi.org/10.4049/jimmunol.144.4.1233
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6
Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7
Autor: N K, Damle, K, Klussman, G, Leytze, S, Myrdal, A, Aruffo, J A, Ledbetter, P S, Linsley
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 152(6)
Costimulation by the CD28 ligand B7/BB1 plays an important role during T cell proliferation primarily by augmenting synthesis of IL-2 and other cytokines. Resting CD4+ T cells express CD28 but not CTLA-4 on their surface. Costimulation of T cells wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::502a9f7169a5f9171d9674a04396e727
https://pubmed.ncbi.nlm.nih.gov/7511623
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7
Costimulation with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 augments activation-induced death of antigen-specific CD4+ T lymphocytes
Autor: N K, Damle, K, Klussman, G, Leytze, A, Aruffo, P S, Linsley, J A, Ledbetter
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 151(5)
Integrin ligands intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) can efficiently costimulate proliferation of resting T cells but not that of Ag-specific T cells. In contrast, CD28 ligand B7 and CD2 ligand le
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::efdb1a7ad1c924ccbcd9760f252e69ff
https://pubmed.ncbi.nlm.nih.gov/7689606
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8
Bispecific receptor globulins, novel tools for the study of cellular interactions. Preparation and characterization of an E-selectin/P-selectin bispecific receptor globulin
Autor: M T, Dietsch, V F, Smith, W L, Cosand, N K, Damle, J A, Ledbetter, P S, Linsley, A, Aruffo
Publikováno v: Journal of immunological methods. 162(1)
In recent years the functional consequences of receptor/ligand interactions have been studied in vitro and in vivo using monospecific recombinant immunoglobulin fusion proteins (recombinant/receptor globulins, Rg). These proteins are encoded by chime
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::85ca2d5e610b614b47bc7e89062bd6cd
https://pubmed.ncbi.nlm.nih.gov/7685365
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9
Proliferation of human T lymphocytes induced with superantigens is not dependent on costimulation by the CD28 counter-receptor B7
Autor: N K, Damle, K, Klussman, G, Leytze, P S, Linsley
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 150(3)
Staphylococcal enterotoxins, also known as superantigens (SAg), bind class II MHC molecules on APC and upon direct cell-to-cell contact stimulate proliferation of T cells expressing appropriate V beta gene products. The T cell surface molecule CD28 b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6fdee41e609c0f423867a5fcfab46199
https://pubmed.ncbi.nlm.nih.gov/7678619
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10
Differential regulatory effects of intercellular adhesion molecule-1 on costimulation by the CD28 counter-receptor B7
Autor: N K, Damle, K, Klussman, P S, Linsley, A, Aruffo, J A, Ledbetter
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 149(8)
Although ligation of the CD3/TCR complex initiates an activation signal in T cells, additional costimulatory signals generated during cell-to-cell interactions with APC transduced via ligation of CD11a/CD18 and CD28 by their specific counter-receptor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::11f934b8e4432dc7575d56c9b92ae24a
https://pubmed.ncbi.nlm.nih.gov/1383317
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