Zobrazeno 1 - 10
of 142
pro vyhledávání: '"N Joan Abbott"'
Autor:
Danni A Gadd, Robert F Hillary, Robert I McGeachan, Sarah E Harris, Daniel L McCartney, N Joan Abbott, Roy A Sherwood, Riccardo E Marioni, Simon R Cox
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
Background: Circulating S100 calcium-binding protein (S100β) is a marker of brain inflammation that has been associated with a range of neurological conditions. To provide insight into the molecular regulation of S100β and its potential causal asso
Externí odkaz:
https://doaj.org/article/aba8554a710746e786e0ab5bcd2d66ec
Autor:
Danni A Gadd, Robert F Hillary, Robert I McGeachan, Sarah E Harris, Daniel L McCartney, N Joan Abbott, Roy A Sherwood, Riccardo E Marioni, Simon R Cox
Publikováno v:
Wellcome Open Research, Vol 6 (2021)
Background: Circulating S100 calcium-binding protein (S100β) is a marker of brain inflammation that has been associated with a range of neurological conditions. To provide insight into the molecular regulation of S100β and its potential causal asso
Externí odkaz:
https://doaj.org/article/47dd8428cea1470e8f25fd8c9a58b659
Autor:
David Dickens, Siti R Yusof, N Joan Abbott, Babette Weksler, Ignacio A Romero, Pierre-Olivier Couraud, Ana Alfirevic, Munir Pirmohamed, Andrew Owen
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64854 (2013)
30% of epilepsy patients receiving antiepileptic drugs (AEDs) are not fully controlled by therapy. The drug transporter hypothesis for refractory epilepsy proposes that P-gp is over expressed at the epileptic focus with a role of P-gp in extruding AE
Externí odkaz:
https://doaj.org/article/353c5f3c8e394cd9b9b95d3bc1e82cab
Autor:
Davide Danovi, Amos Folarin, Sabine Gogolok, Christine Ender, Ahmed M O Elbatsh, Pär G Engström, Stefan H Stricker, Sladjana Gagrica, Ana Georgian, Ding Yu, Kin Pong U, Kevin J Harvey, Patrizia Ferretti, Patrick J Paddison, Jane E Preston, N Joan Abbott, Paul Bertone, Austin Smith, Steven M Pollard
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77053 (2013)
Glioblastoma multiforme (GBM) is the most common primary brain cancer in adults and there are few effective treatments. GBMs contain cells with molecular and cellular characteristics of neural stem cells that drive tumour growth. Here we compare resp
Externí odkaz:
https://doaj.org/article/19166962924b408289d08b363d1c7682
Publikováno v:
Drug Delivery to the Brain ISBN: 9783030887728
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::193f1343b1e5cd67276521e29540865e
https://doi.org/10.1007/978-3-030-88773-5_8
https://doi.org/10.1007/978-3-030-88773-5_8
Autor:
N. Joan Abbott
Publikováno v:
Drug Delivery to the Brain ISBN: 9783030887728
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beeaa3f4fa4eaa723723be6731684731
https://doi.org/10.1007/978-3-030-88773-5_1
https://doi.org/10.1007/978-3-030-88773-5_1
Autor:
Charles Turner, Luke Wainwright, Jane E. Preston, Simon J R Heales, R Neil Dalton, N. Joan Abbott, Ana R. Georgian, Iain P. Hargreaves
Publikováno v:
Journal of Clinical Medicine
Volume 9
Issue 10
Journal of Clinical Medicine, Vol 9, Iss 3236, p 3236 (2020)
Volume 9
Issue 10
Journal of Clinical Medicine, Vol 9, Iss 3236, p 3236 (2020)
Primary coenzyme Q10 (CoQ10) deficiency is unique among mitochondrial respiratory chain disorders in that it is potentially treatable if high-dose CoQ10 supplements are given in the early stages of the disease.While supplements improve peripheral abn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bfe025687dad367a2d764c12a322796
Autor:
Wendy Butcher, Lyn M. O'Brien, F. Javier Salguero, E. Diane Williamson, Francesca Modino, Stuart Woods, Ana R. Georgian, Craig W. Roberts, Jane E. Preston, N. Joan Abbott, Riccardo V. D'Elia
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 324
The field of brain drug delivery faces many challenges that hinder development and testing of novel therapies for clinically important central nervous system disorders. Chief among them is how to deliver large biologics across the highly restrictive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0884c9de956f00202bbc5fba44381bd1
https://pubmed.ncbi.nlm.nih.gov/32512014
https://pubmed.ncbi.nlm.nih.gov/32512014
Publikováno v:
Abbott, N J, Nicholson, C & Verkhratsky, A 2020, ' Introduction : Special Issue in Honor of Eva Syková ', Neurochemical research, vol. 45, no. 1 . https://doi.org/10.1007/s11064-019-02924-z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6f74fdf21256e0a6db32326c567cba
https://www.research.manchester.ac.uk/portal/en/publications/introduction(d798234e-89f4-4e55-8887-dbf223c9e8b0).html
https://www.research.manchester.ac.uk/portal/en/publications/introduction(d798234e-89f4-4e55-8887-dbf223c9e8b0).html
Autor:
Simon R. Cox, Mike Allerhand, Stuart J. Ritchie, Susana Muñoz Maniega, Maria Valdés Hernández, Sarah E. Harris, David Alexander Dickie, Devasuda Anblagan, Benjamin S. Aribisala, Zoe Morris, Roy Sherwood, N. Joan Abbott, John M. Starr, Mark E. Bastin, Joanna M. Wardlaw, Ian J. Deary
Publikováno v:
Neurobiology of Aging
Elevated serum and cerebrospinal fluid concentrations of S100β, a protein predominantly found in glia, are associated with intracranial injury and neurodegeneration, although concentrations are also influenced by several other factors. The longitudi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::516a7ed82de28ed3642f370274362804
http://europepmc.org/articles/PMC6075468
http://europepmc.org/articles/PMC6075468