Zobrazeno 1 - 10
of 13
pro vyhledávání: '"N J Simmonds"'
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0212779 (2019)
ObjectiveCystic fibrosis associated liver disease (CFLD) is the third largest cause of mortality in CF. Our aim was to define the burden of CFLD in the UK using national registry data and identify risk factors for progressive disease.MethodsA longitu
Externí odkaz:
https://doaj.org/article/0e8f954737a1485babdbd2bcb923398d
Publikováno v:
Paediatric Respiratory Reviews. 42:29-34
There is now increased knowledge and experience of newborn screening around the world. There is also a better understanding of CF gene analysis, informed by international databases. This has resulted in a small number of children and adults having th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce38ec2ebf752504ed479043c100830d
https://doi.org/10.1016/j.prrv.2021.11.002
https://doi.org/10.1016/j.prrv.2021.11.002
Publikováno v:
Alimentary Pharmacology & Therapeutics. 13:363-372
Background : The therapeutic efficacy of 5-aminosalicylic acid in inflammatory bowel disease may be related to its antioxidant properties. Aim : To compare in vitro the antioxidant effects of conventional drugs (5-aminosalicylic acid, corticosteroids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bae4c20324fde6224bba7145344f589f
https://doi.org/10.1046/j.1365-2036.1999.00484.x
https://doi.org/10.1046/j.1365-2036.1999.00484.x
Publikováno v:
European Respiratory Journal. 27:427-429
Pneumothorax is a relatively common condition that is usually managed either conservatively, by chest tube drainage or, if a refractory air leak persists, then with cardiothoracic intervention. However, there is a small group of patients with a persi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6f9ff1cd56ae14706a01eea290d3af
https://doi.org/10.1183/09031936.06.00020905
https://doi.org/10.1183/09031936.06.00020905
Autor:
I. F. Laurenson, T. R.J. Stevens, P. J. Maddison, Jana James, N. J. Simmonds, D. S. Rampton, D. A. Mccarthy
Publikováno v:
Gut. 33:502-506
Raised circulating von Willebrand factor is a recognised marker of vascular injury. To evaluate the role of vascular injury in the pathogenesis of inflammatory bowel disease, serum von Willebrand factor in Crohn's disease, ulcerative colitis, confirm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ebd46f402ae86ac3a322611d264690
https://doi.org/10.1136/gut.33.4.502
https://doi.org/10.1136/gut.33.4.502
Publikováno v:
Alimentary pharmacologytherapeutics. 13(3)
The therapeutic efficacy of 5-aminosalicylic acid in inflammatory bowel disease may be related to its antioxidant properties.To compare in vitro the antioxidant effects of conventional drugs (5-aminosalicylic acid, corticosteroids, metronidazole), wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc65489255b10ac11681f5d851f7f152
https://pubmed.ncbi.nlm.nih.gov/10102970
https://pubmed.ncbi.nlm.nih.gov/10102970
Autor:
N J Simmonds, B I Hoffbrand
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 53:998-1000
Granulomatous muscle disease is most commonly seen in sarcoidosis, but may be seen in association with a wide variety of other disorders or in isolation. Patients with granulomatous myositis usually present with slowly progressive muscle pain and wea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4da7ae4dee1405708fd3af30e3cf23
https://doi.org/10.1136/jnnp.53.11.998
https://doi.org/10.1136/jnnp.53.11.998
Autor:
M. T. Sheaff, T. R. J. Stevens, D. S. Rampton, Nicholas Banatvala, I. F. Laurenson, N. J. Simmonds, G. R. Davies, D. R. Blake
To determine if reactive oxygen metabolites have a pathogenic role in Helicobacter pylori (H pylori) related gastroduodenal disease, this study measured their production in antral mucosal biopsy specimens. Two related chemiluminescence techniques wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f890ee32c860e080401dc841f1014fd2
https://europepmc.org/articles/PMC1374491/
https://europepmc.org/articles/PMC1374491/
Autor:
Peter M. George, Margaret E. Hodson, N J Simmonds, Winston Banya, Diana Bilton, Paul Cullinan, N Pareek
Publikováno v:
The BMJ
Objectives To evaluate the survival of patients with cystic fibrosis whose lung function has deteriorated to a forced expiratory volume in one second (FEV1) below 30% predicted in the recent treatment era and to explore factors associated with any ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2755a85140750239dd1b1dfaaa58480c
https://doi.org/10.1136/bmj.d1008
https://doi.org/10.1136/bmj.d1008
To investigate the hypothesis that reactive oxygen metabolites are important in the pathophysiology of duodenal ulcer disease, their production by duodenal mucosal biopsy specimens was measured using luminol and lucigenin amplified chemiluminescence.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13ef784041672b8289fd14cd69c6a6e
https://europepmc.org/articles/PMC1379529/
https://europepmc.org/articles/PMC1379529/