Zobrazeno 1 - 10 of 42 pro vyhledávání: '"N J Samani"'
1
Alcohol consumption and telomere length: Mendelian randomization clarifies alcohol’s effects
Autor: A. Topiwala, B. Taschler, K. P. Ebmeier, S. Smith, H. Zhou, D. F. Levey, V. Codd, N. J. Samani, J. Gelernter, T. E. Nichols, S. Burgess
Alcohol’s impact on telomere length, a proposed marker of biological aging, is unclear. We performed the largest observational study to date (in n = 245,354 UK Biobank participants) and compared findings with Mendelian randomization (MR) estimates.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24c2ead3a8b256bb63e010dd6a2509b
https://ora.ox.ac.uk/objects/uuid:26d792ab-449e-4f9d-9ac3-87b7e02d22ec
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2
Pathophysiological pathways in patients with heart failure and atrial fibrillation
Autor: Iziah E Sama, Carolyn S.P. Lam, Marco Metra, Michiel Rienstra, Vicente Artola Arita, Isabelle C. Van Gelder, Jozine M. ter Maaten, John G.F. Cleland, Mariëlle Kloosterman, Stefan D. Anker, Hans L A Nienhuis, Chim C. Lang, Peter van der Meer, Bernadet T. Santema, Adriaan A. Voors, Leong L. Ng, Gerasimos Filippatos, N J Samani, Maarten P. van den Berg, Dirk J. van Veldhuisen, Kenneth Dickstein, Faiez Zannad
Publikováno v: Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2021, pp.cvab331. ⟨10.1093/cvr/cvab331⟩
Cardiovascular Research, 118(11). Oxford University Press
Cardiovascular Research, 2021, pp.cvab331. ⟨10.1093/cvr/cvab331⟩
Cardiovascular Research (CVR)
Aims:\ud Atrial fibrillation (AF) and heart failure (HF) are two growing epidemics that frequently co-exist. We aimed to gain insights into underlying pathophysiological pathways in HF patients with AF by comparing circulating biomarkers using pathwa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5694c70efd0e04a50c2fd849155fdb36
https://hal.univ-lorraine.fr/hal-03411938/file/cvab331.pdf
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3
Non-adherence to heart failure medications predicts clinical outcomes: assessment in a single spot urine sample by liquid chromatography-tandem mass spectrometry (results of a prospective multicentre study)
Autor: Prashanth Patel, Dan Lane, Pankaj Gupta, Chim C. Lang, Adriaan A. Voors, Marco Metra, Kenneth Dickstein, Faiez Zannad, Gerasimos Filippatos, Donald J. L. Jones, John G.F. Cleland, N J Samani, Leong L. Ng, Iain B. Squire, Stefan D. Anker, Dirk J. van Veldhuisen
Publikováno v: European Journal of Heart Failure, 23(7), 1182-1190. Wiley
Aims: \ud Liquid chromatography-mass spectrometry (LC-MS/MS) is an objective new technique to assess non-adherence to medications. We used this method to study the prevalence, predictors and outcomes of non-adherence in patients with heart failure wi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9e2c6709ad56fef4b8a24921c22d17
https://pubmed.ncbi.nlm.nih.gov/33759308
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4
The clinical significance of interleukin-6 in heart failure: results from the BIOSTAT-CHF study
Autor: George Markousis-Mavrogenis, Adriaan A. Voors, Marco Metra, Wouter Ouwerkerk, Rahul Kakkar, Gerasimos Filippatos, Matt Devalaraja, Peter van der Meer, Chim C. Lang, John G.F. Cleland, Piotr Ponikowski, Aeilko H. Zwinderman, N J Samani, Kenneth Dickstein, Faiez Zannad, Stefan D. Anker, Leong L. Ng, Dirk J. van Veldhuisen, Pim van der Harst, Jasper Tromp, Hans L. Hillege
Publikováno v: European journal of heart failure, 21(8), 965-973. Wiley-Blackwell
European Journal of Heart Failure, 21(8), 965-973. Wiley
Aims:\ud \ud Inflammation is a central process in the pathophysiology of heart failure (HF), but trials targeting tumour necrosis factor (TNF)‐α were largely unsuccessful. Interleukin (IL)‐6 is an important inflammatory mediator and might consti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ee77797734ca5f5e65d9f8f7dc11ed
https://pubmed.ncbi.nlm.nih.gov/31087601
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5
Daily remote ischaemic conditioning following acute myocardial infarction: a randomised controlled trial
Autor: Jayanth R. Arnold, Gerry P McCann, Leong L. Ng, N J Samani, Kamal Chitkara, Florence Y. Lai, Glenn Rodrigo, A P Vanezis, Radek Debiec, Jamal N Khan, John G Coghlan, Simon Hetherington, Sheraz A Nazir
Publikováno v: Heart
BackgroundRemote ischaemic conditioning (rIC) is a cardioprotective tool which has shown promise in preclinical and clinical trials in the context of acute ischaemia. Repeated rIC post myocardial infarction may provide additional benefits which have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e238c969ae8a865518c5902a9ee08707
https://pubmed.ncbi.nlm.nih.gov/29748420
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6
Coronary angiography in worsening heart failure: determinants, findings and prognostic implications
Autor: Chim C. Lang, Piotr Ponikowski, Stefan D. Anker, Dirk J. van Veldhuisen, Kenneth Dickstein, Faiez Zannad, João Pedro Ferreira, Gerasimos Filippatos, Marco Metra, Abhinav Sharma, Hans L. Hillege, Aeilko H. Zwinderman, Adriaan A. Voors, N J Samani, Patrick Rossignol, John G.F. Cleland, Biniyam G. Demissei, Leong L. Ng, Nicolas Girerd
Publikováno v: Heart (British Cardiac Society), 104(7), 606-613. BMJ Publishing Group
Heart, 104(7), 606-613. BMJ PUBLISHING GROUP
ObjectivesCoronary angiography is regularly performed in patients with worsening signs and/or symptoms of heart failure (HF). However, little is known on the determinants, findings and associated clinical outcomes of coronary angiography performed in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a53df9a8e593f5346a695c32fdc13c
http://hdl.handle.net/11379/504352
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7
Determinants and clinical outcome of uptitration of ACE-inhibitors and beta-blockers in patients with heart failure
Autor: Chim C. Lang, Hans L. Hillege, Leong L. Ng, N J Samani, Stefan D. Anker, J. M. ter Maaten, A. H. Zwinderman, A. A. Voors, Kenneth Dickstein, D. J. Van Veldhuisen, Piotr Ponikowski, F Zannad, Wouter Ouwerkerk, P. van der Harst, M. Metra, John G.F. Cleland, G Filippatos
Publikováno v: European Heart Journal, 38(24), 1883-1890b. Oxford University Press
European heart journal, 38(24), 1883-1890B. Oxford University Press
Introduction Despite clear guidelines recommendations, most patients with heart failure and reduced ejection–fraction (HFrEF) do not attain guideline-recommended target doses. We aimed to investigate characteristics and for treatment-indication-bia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c29e6d5782718a7ae525cd628db1c47
https://doi.org/10.1093/eurheartj/ehx026
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9
The Epithelial Sodium Channel γ-Subunit Gene and Blood Pressure
Autor: Maciej Tomaszewski, Fadi J. Charchar, Peter S. Braund, Steven C. Hunt, Katrina J Scurrah, Cara J Busst, Lisa D.S. Bloomer, Paul N. Hopkins, Justine A. Ellis, Stephen B. Harrap, Timothy A. Barnes, N J Samani
Publikováno v: Hypertension. 58:1073-1078
Variants in the gene encoding the γ-subunit of the epithelial sodium channel ( SCNN1G) are associated with both Mendelian and quantitative effects on blood pressure. Here, in 4 cohorts of 1611 white European families composed of a total of 8199 indi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15152e936e420bb7c543f73b9c816456
https://doi.org/10.1161/hypertensionaha.111.176370
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