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Autor:
N Yu, D Sriranganathan, G J Walker, A Sazonovs, H Wilding, N A Kennedy, T Ahmad, R K Boyapati, J P Segal, N J S Ding
Publikováno v:
Journal of Crohn's and Colitis. 17:i569-i570
Background Nudix hydrolase 15 (NUDT15) genetic polymorphisms confer an increased risk of thiopurine-induced myelosuppression (TIM). Thiopurines continue to be widely used as maintenance therapy for inflammatory bowel disease (IBD) in patients worldwi