Zobrazeno 1 - 10
of 815
pro vyhledávání: '"N J Rothwell"'
Autor:
Cai Song
Publikováno v:
Human Psychopharmacology: Clinical and Experimental. 10:161-161
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14d11574b123e5e82939d1cb26e9a295
https://doi.org/10.1002/hup.470100216
https://doi.org/10.1002/hup.470100216
Publikováno v:
Mediators of Inflammation, Vol 3, Iss 5, Pp 353-357 (1994)
Modification of endogenous eicosanoid synthesis by dietary n-3 fatty acid supplementation reduces febrile responses, but the mechanisms underlying these effects in vivo have not been determined. In the present study, local inflammation was induced by
Externí odkaz:
https://doaj.org/article/ea702d3a3d804aa79811a101f145657f
Autor:
Ma, Hongyan1,2,3 (AUTHOR), Jia, Huiyang1,2,3 (AUTHOR), Zou, Wenzheng1,2,3 (AUTHOR), Ji, Fen1,2,3 (AUTHOR), Wang, Wenwen1,2,3 (AUTHOR), Zhao, Jinyue1,2,3 (AUTHOR), Yuan, Chenqi1,2,3 (AUTHOR), Jiao, Jianwei1,2,3,4 (AUTHOR) jwjiao@ioz.ac.cn
Publikováno v:
Advanced Science. 9/18/2024, Vol. 11 Issue 35, p1-21. 21p.
Publikováno v:
British journal of pharmacology. 156(7)
The inflammatory cytokine interleukin-1 (IL-1) has profound actions in the brain, causing neuronal cell death and exacerbating brain damage. While circulating levels are normally low, IL-1 can be produced on the vascular side of the brain endothelium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8100be37ab7a8c8a6d76f4079019affd
https://pubmed.ncbi.nlm.nih.gov/19298391
https://pubmed.ncbi.nlm.nih.gov/19298391
Publikováno v:
British journal of pharmacology. 153(4)
Interleukin (IL)-1 is a key mediator of inflammatory and host defence responses and its effects in the brain are mediated primarily via effects on glia. IL-1 induces release of inflammatory mediators such as IL-6 from glia via the type-1 receptor (IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c959c6f54642bb2e6178e4f0a647ef37
https://pubmed.ncbi.nlm.nih.gov/18059318
https://pubmed.ncbi.nlm.nih.gov/18059318
Autor:
C B, Lawrence, N J, Rothwell
Publikováno v:
Journal of neuroendocrinology. 13(6)
The cytokine interleukin-1 (IL-1), which mediates many responses to infection and injury, induces anorexia and fever through direct actions in the central nervous system. The melanocortin neuropeptides, such as alpha melanocyte-stimulating hormone (a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4a40ffa3895299ddb06cad62b810cc4
https://pubmed.ncbi.nlm.nih.gov/11412335
https://pubmed.ncbi.nlm.nih.gov/11412335
Publikováno v:
Glia. 33(2)
The objective of this study was to investigate the actions of exogenous and endogenous IL-10 on inflammatory responses of glia. Studies were conducted in primary, mixed glial cultures from C57BL/6 (wild-type [WT]) and IL-10-deficient C57BL/6 (IL-10 k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2325368c15537a0b49cab567d30d84ee
https://pubmed.ncbi.nlm.nih.gov/11180507
https://pubmed.ncbi.nlm.nih.gov/11180507
Publikováno v:
Glia. 25(4)
Interleukin-1 beta (IL-1beta) has been proposed as a mediator of several forms of brain damage, including that induced by excitotoxins. In vitro studies suggest that glial cells are the effector cells of IL-1beta-mediated neurodegeneration. We have i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e70f1a9a1dfec7316aa7cb03d56b1fb2
https://pubmed.ncbi.nlm.nih.gov/10028914
https://pubmed.ncbi.nlm.nih.gov/10028914
Autor:
N J, Rothwell
Publikováno v:
The Journal of physiology. 514
Given at the Meeting of the Physiological Society held at the University of Southampton on 10 September 1998
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9840588f923404b5a14211d17b76015c
https://pubmed.ncbi.nlm.nih.gov/9831712
https://pubmed.ncbi.nlm.nih.gov/9831712
Autor:
H R, Anforth, R M, Bluthe, A, Bristow, S, Hopkins, M J, Lenczowski, G, Luheshi, J, Lundkvist, B, Michaud, Y, Mistry, A M, Van Dam, C, Zhen, R, Dantzer, S, Poole, N J, Rothwell, F J, Tilders, E E, Wollman
Publikováno v:
European cytokine network. 9(3)
IL-1alpha and IL-1beta have potent effects on the central nervous system resulting in fever, activation of the hypothalamic-pituitary-adrenal axis and behavioural depression. These effects have mainly been studied in rats, using recombinant human and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::741b04b75955c305d803ff3c2bd9f5e4
https://pubmed.ncbi.nlm.nih.gov/9831177
https://pubmed.ncbi.nlm.nih.gov/9831177